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Protein
Submitted name:

Adenylate/guanylate cyclase

Gene

LA_0027

Organism
Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. phosphorus-oxygen lyase activity Source: InterPro

GO - Biological processi

  1. cyclic nucleotide biosynthetic process Source: InterPro
  2. intracellular signal transduction Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

BioCyciLINT189518:GJBB-24-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Adenylate/guanylate cyclaseImported
Gene namesi
Ordered Locus Names:LA_0027Imported
OrganismiLeptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)Imported
Taxonomic identifieri189518 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesLeptospiraceaeLeptospira
ProteomesiUP000001408: Chromosome I

Interactioni

Protein-protein interaction databases

STRINGi189518.LA0027.

Structurei

3D structure databases

ProteinModelPortaliQ8FA10.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000118029.
InParanoidiQ8FA10.
KOiK01768.
OMAiILISHHT.
OrthoDBiEOG6JDW7F.

Family and domain databases

Gene3Di3.30.70.1230. 1 hit.
InterProiIPR011623. 7TMR_DISM_rcpt_extracell_dom1.
IPR001054. A/G_cyclase.
IPR029787. Nucleotide_cyclase.
[Graphical view]
PfamiPF07695. 7TMR-DISM_7TM. 1 hit.
PF00211. Guanylate_cyc. 1 hit.
[Graphical view]
SMARTiSM00044. CYCc. 1 hit.
[Graphical view]
SUPFAMiSSF55073. SSF55073. 1 hit.
PROSITEiPS50125. GUANYLATE_CYCLASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8FA10-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIRLIRTFAY ILVFWILCSC VSDSDRFQNL DLITQAEWTA SLGNHLKDRL
60 70 80 90 100
EKSNVQKSFL KNKKEKLNIE TNSREKESKD FKNWKLITRF PVNFNFLFSI
110 120 130 140 150
PKQSGFHDVT VKVEFSIHSD SIFLTFLKQP TAIYFPDLGE NWELYLNGIP
160 170 180 190 200
IRKEKFLKQT DTGDLIPSVR RSLKSVILPI PSGVLKEGKN TILIYMIGES
210 220 230 240 250
DFTHYIPNEH FGFYHSKGYK ILSLEQIYES TFEYWDLLLY GIYTIFGIYH
260 270 280 290 300
IYFYFIRRKD LYYLYFGLFS FFSSVYFFSS SNLIFQKFVN PNPELDSSLF
310 320 330 340 350
FRMQYSSLTL IFPSFYYFLK DYFSPKEKGS MIASFFVIFL IGLFFAFLTV
360 370 380 390 400
PFSWVHIAFK ICQILAICFS VYILFFSIQT VRKKKQDARK ILVGICVCIV
410 420 430 440 450
FSTWELYGSV FENAKYHSTF FKLVYLFFII SIASTLVLRY VQLYKDAQLL
460 470 480 490 500
NKYLIDQKEA FYRFVPVDFI RIIDRESPIS ISVGDSKEKS MTVLTSCIRN
510 520 530 540 550
FASLSKTVPL NQTITFLNSY LSEMEELVYK TTGFVDKYIG NEILALFGDY
560 570 580 590 600
DERAAKENFN SADNAVESAI KMVNAIRSGK LVKNFLIPSF WNLEIGIGIN
610 620 630 640 650
TGSVILGTVG SERRIDTTVI GDAVDLSSGL RSLTALYKSK ILVSHHTYLR
660 670 680 690 700
LHRMSEIGIR MIDSVILKER DQAVDIYEVI ESDPESIKEF KLKTLELLSQ
710 720 730 740 750
GILEYKSKRF DEAAKIFRQL YREEPKDFIS MIYLKRCKLY SSKPPDENWD

GVFRFQTK
Length:758
Mass (Da):88,485
Last modified:March 1, 2003 - v1
Checksum:i043D568226F585C0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE010300 Genomic DNA. Translation: AAN47226.1.
RefSeqiNP_710208.1. NC_004342.2.

Genome annotation databases

EnsemblBacteriaiAAN47226; AAN47226; LA_0027.
GeneIDi1149370.
KEGGilil:LA_0027.
PATRICi22380893. VBILepInt91350_0031.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE010300 Genomic DNA. Translation: AAN47226.1.
RefSeqiNP_710208.1. NC_004342.2.

3D structure databases

ProteinModelPortaliQ8FA10.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi189518.LA0027.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN47226; AAN47226; LA_0027.
GeneIDi1149370.
KEGGilil:LA_0027.
PATRICi22380893. VBILepInt91350_0031.

Phylogenomic databases

HOGENOMiHOG000118029.
InParanoidiQ8FA10.
KOiK01768.
OMAiILISHHT.
OrthoDBiEOG6JDW7F.

Enzyme and pathway databases

BioCyciLINT189518:GJBB-24-MONOMER.

Family and domain databases

Gene3Di3.30.70.1230. 1 hit.
InterProiIPR011623. 7TMR_DISM_rcpt_extracell_dom1.
IPR001054. A/G_cyclase.
IPR029787. Nucleotide_cyclase.
[Graphical view]
PfamiPF07695. 7TMR-DISM_7TM. 1 hit.
PF00211. Guanylate_cyc. 1 hit.
[Graphical view]
SMARTiSM00044. CYCc. 1 hit.
[Graphical view]
SUPFAMiSSF55073. SSF55073. 1 hit.
PROSITEiPS50125. GUANYLATE_CYCLASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 56601Imported.

Entry informationi

Entry nameiQ8FA10_LEPIN
AccessioniPrimary (citable) accession number: Q8FA10
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: January 7, 2015
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.