SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8F9Q1

- TRMB_LEPIN

UniProt

Q8F9Q1 - TRMB_LEPIN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

tRNA (guanine-N(7)-)-methyltransferase

Gene
trmB, LA_0140
Organism
Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA By similarity.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei48 – 481S-adenosyl-L-methionine By similarity
Binding sitei73 – 731S-adenosyl-L-methionine By similarity
Binding sitei100 – 1001S-adenosyl-L-methionine By similarity
Active sitei123 – 1231 By similarity
Binding sitei123 – 1231S-adenosyl-L-methionine By similarity
Binding sitei127 – 1271Substrate By similarity
Binding sitei159 – 1591Substrate By similarity

GO - Molecular functioni

  1. tRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciLINT189518:GJBB-127-MONOMER.
UniPathwayiUPA00989.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA (guanine-N(7)-)-methyltransferase (EC:2.1.1.33)
Alternative name(s):
tRNA (guanine(46)-N(7))-methyltransferase
tRNA(m7G46)-methyltransferase
Gene namesi
Name:trmB
Ordered Locus Names:LA_0140
OrganismiLeptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Taxonomic identifieri189518 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesLeptospiraceaeLeptospira
ProteomesiUP000001408: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 217217tRNA (guanine-N(7)-)-methyltransferaseUniRule annotationPRO_0000171342Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi189518.LA0140.

Structurei

3D structure databases

ProteinModelPortaliQ8F9Q1.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0220.
HOGENOMiHOG000040678.
KOiK03439.
OMAiIVELAMN.
OrthoDBiEOG6K6VBC.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01057. tRNA_methyltr_TrmB.
InterProiIPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view]
PfamiPF02390. Methyltransf_4. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00091. TIGR00091. 1 hit.
PROSITEiPS51625. SAM_MT_TRMB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8F9Q1-1 [UniParc]FASTAAdd to Basket

« Hide

MVQDLEQKLW SIASGIPFSS DYFLQASPIR KLKKENLFSK VFETYFLELG    50
SGWGEVAISM ALQRPNTGFI LMEKKFDRIR HTIREIEKHS LDNVKILCVN 100
FNWFLEEVFE ENLFSEILLN FPDPWPKKRH HKKRTVNSKF LESLKILLPE 150
KGKFYFATDY GPYARKVIRL FRDSKAFSPE KVELKSERNE IPVSHFERKK 200
REEGKRIYYI DRVLVQK 217
Length:217
Mass (Da):25,913
Last modified:March 1, 2003 - v1
Checksum:i5DDFFCAEBEFAB967
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE010300 Genomic DNA. Translation: AAN47339.1.
RefSeqiNP_710321.1. NC_004342.2.

Genome annotation databases

EnsemblBacteriaiAAN47339; AAN47339; LA_0140.
GeneIDi1149483.
KEGGilil:LA_0140.
PATRICi22381125. VBILepInt91350_0143.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE010300 Genomic DNA. Translation: AAN47339.1 .
RefSeqi NP_710321.1. NC_004342.2.

3D structure databases

ProteinModelPortali Q8F9Q1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 189518.LA0140.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAN47339 ; AAN47339 ; LA_0140 .
GeneIDi 1149483.
KEGGi lil:LA_0140.
PATRICi 22381125. VBILepInt91350_0143.

Phylogenomic databases

eggNOGi COG0220.
HOGENOMi HOG000040678.
KOi K03439.
OMAi IVELAMN.
OrthoDBi EOG6K6VBC.

Enzyme and pathway databases

UniPathwayi UPA00989 .
BioCyci LINT189518:GJBB-127-MONOMER.

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
HAMAPi MF_01057. tRNA_methyltr_TrmB.
InterProi IPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view ]
Pfami PF02390. Methyltransf_4. 1 hit.
[Graphical view ]
SUPFAMi SSF53335. SSF53335. 1 hit.
TIGRFAMsi TIGR00091. TIGR00091. 1 hit.
PROSITEi PS51625. SAM_MT_TRMB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 56601.

Entry informationi

Entry nameiTRMB_LEPIN
AccessioniPrimary (citable) accession number: Q8F9Q1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 16, 2003
Last sequence update: March 1, 2003
Last modified: June 11, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi