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Protein

Methylglyoxal synthase

Gene

mgsA

Organism
Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Glycerone phosphate = methylglyoxal + phosphate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei69UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Names & Taxonomyi

Protein namesi
Recommended name:
Methylglyoxal synthaseUniRule annotation (EC:4.2.3.3UniRule annotation)
Short name:
MGSUniRule annotation
Gene namesi
Name:mgsAUniRule annotation
Ordered Locus Names:LA_0909
OrganismiLeptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Taxonomic identifieri189518 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesLeptospiralesLeptospiraceaeLeptospira
Proteomesi
  • UP000001408 Componenti: Chromosome I

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001786331 – 148Methylglyoxal synthaseAdd BLAST148

Interactioni

Protein-protein interaction databases

STRINGi189518.LA_0909.

Structurei

3D structure databases

ProteinModelPortaliQ8F7N5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methylglyoxal synthase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108Z5K. Bacteria.
COG1803. LUCA.
HOGENOMiHOG000283729.
InParanoidiQ8F7N5.
KOiK01734.
OMAiMTPQPHE.

Family and domain databases

CDDicd01422. MGS. 1 hit.
Gene3Di3.40.50.1380. 1 hit.
HAMAPiMF_00549. Methylglyoxal_synth. 1 hit.
InterProiIPR004363. Methylgl_synth.
IPR018148. Methylglyoxal_synth_AS.
IPR011607. MGS-like_dom.
[Graphical view]
PfamiPF02142. MGS. 1 hit.
[Graphical view]
PIRSFiPIRSF006614. Methylglyox_syn. 1 hit.
SMARTiSM00851. MGS. 1 hit.
[Graphical view]
SUPFAMiSSF52335. SSF52335. 1 hit.
TIGRFAMsiTIGR00160. MGSA. 1 hit.
PROSITEiPS01335. METHYLGLYOXAL_SYNTH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8F7N5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKEVSVPAIK RIVLIAHDNR KEDLVNWVKT HREILSKHQL YGTGTTGKLI
60 70 80 90 100
SEETELPVYR FLSGPLGGDQ QIGAKIAEGD LDIVIFFWDP LTAQPHDPDV
110 120 130 140
KALLRIAVLY NVPMACNRST ADYMISSPQF TKTYKKILLS YNTKVKKD
Length:148
Mass (Da):16,727
Last modified:March 1, 2003 - v1
Checksum:i2A32477D8EB8774E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE010300 Genomic DNA. Translation: AAN48108.1.
RefSeqiNP_711090.1. NC_004342.2.
WP_000665953.1. NC_004342.2.

Genome annotation databases

EnsemblBacteriaiAAN48108; AAN48108; LA_0909.
GeneIDi1150252.
KEGGilil:LA_0909.
PATRICi22382666. VBILepInt91350_0910.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE010300 Genomic DNA. Translation: AAN48108.1.
RefSeqiNP_711090.1. NC_004342.2.
WP_000665953.1. NC_004342.2.

3D structure databases

ProteinModelPortaliQ8F7N5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi189518.LA_0909.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN48108; AAN48108; LA_0909.
GeneIDi1150252.
KEGGilil:LA_0909.
PATRICi22382666. VBILepInt91350_0910.

Phylogenomic databases

eggNOGiENOG4108Z5K. Bacteria.
COG1803. LUCA.
HOGENOMiHOG000283729.
InParanoidiQ8F7N5.
KOiK01734.
OMAiMTPQPHE.

Family and domain databases

CDDicd01422. MGS. 1 hit.
Gene3Di3.40.50.1380. 1 hit.
HAMAPiMF_00549. Methylglyoxal_synth. 1 hit.
InterProiIPR004363. Methylgl_synth.
IPR018148. Methylglyoxal_synth_AS.
IPR011607. MGS-like_dom.
[Graphical view]
PfamiPF02142. MGS. 1 hit.
[Graphical view]
PIRSFiPIRSF006614. Methylglyox_syn. 1 hit.
SMARTiSM00851. MGS. 1 hit.
[Graphical view]
SUPFAMiSSF52335. SSF52335. 1 hit.
TIGRFAMsiTIGR00160. MGSA. 1 hit.
PROSITEiPS01335. METHYLGLYOXAL_SYNTH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMGSA_LEPIN
AccessioniPrimary (citable) accession number: Q8F7N5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: March 1, 2003
Last modified: November 2, 2016
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.