Q8F7H9 (Q8F7H9_LEPIN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Exodeoxyribonuclease V beta chain EMBL AAN48165.1

Gene names

Ordered Locus Names:

LA_0966

Organism

Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601) [Reference proteome] [HAMAP] EMBL AAN48165.1

Taxonomic identifier

189518 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Spirochaetes › Spirochaetia › Spirochaetales › Leptospiraceae › Leptospira › Leptospira interrogans › Leptospira interrogans serovar Lai

Protein attributes

Sequence length	1046 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity	ATP + H2O = ADP + phosphate. SAAS SAAS000212
Sequence similarities	Contains 1 uvrD-like helicase ATP-binding domain. SAAS SAAS000212 Contains 1 uvrD-like helicase C-terminal domain. SAAS SAAS000212

Ontologies

Keywords
Biological process	DNA damage DNA repair SAAS SAAS000212
Ligand	ATP-binding Nucleotide-binding
Molecular function	Exonuclease SAAS SAAS000212 Helicase SAAS SAAS000212 Hydrolase Nuclease
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	DNA repair Inferred from electronic annotation. Source: UniProtKB-KW nucleic acid phosphodiester bond hydrolysis Inferred from electronic annotation. Source: GOC
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATP-dependent DNA helicase activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro exonuclease activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8F7H9 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 642ADEDB7DE67DA8	FASTA	1,046	122,763
	10 20 30 40 50 60 MNVSRTYKFK SSFIEASAGT GKTYTIMEIV IDLILEHKIP LTQILILTYT EKAAGELKER 70 80 90 100 110 120 LRKKLISSGL TKEARELDQV TISTIHGFCN TILKEYPVET ETHTNWILTD ALERLNIALY 130 140 150 160 170 180 KLQHEEWNSW VDPEKLEDFI LSSKYRFKKE NILISASKLL SGKKYKYSNE TTTMTSETFL 190 200 210 220 230 240 QKTALIIADM VLKEFKTSEW MSYDQMILKT RDSLENPRLR KALQSRYRVG ILDEFQDTDG 250 260 270 280 290 300 AQYEIFKRLF LESNDDRALY LIGDPKQSIY GFRGADIGIY LQAKEELKKH KAEEISLNVN 310 320 330 340 350 360 YRSVPELIRA YNEIFGGKSG KQSFFPILEQ SIPIQYEPVF APKENIKVLL SDKQKQGPIQ 370 380 390 400 410 420 IVRFTGKDFW NTQDAKNAWG QFISEEILKL IHKEDPFTYQ VAEGDLYYVE KKLKLREIAV 430 440 450 460 470 480 LVKSKSEGKL AEQFLKLRGI PCSFYKQEGI YQSAESYQIS NIFECLLDPN KPSSYRKLLL 490 500 510 520 530 540 GDLFQIHPAH LPYFDEHSID SYEKSILDRW KTLSMDRKFS ELFRSIEEDS RIFLTEDATD 550 560 570 580 590 600 IDWERKRTNY RQIFRRLLQF QIANQADLEE ILEELKLLQK SFKNEEELPL FEKETEKDAV 610 620 630 640 650 660 QILTLHASKG LEWPVVFLFN LSGDYIPEVY DYPFVDKDGK LSWKLSLWDN EEEKKISKEI 670 680 690 700 710 720 YSNQSLNENK RLLYVGITRS KVRIYLPFYT PLNNWKTRDS AYYKILYPRL QSILENEIDT 730 740 750 760 770 780 DLFHVVSWAP TPFDSTDPKR IDWNLDSEIC FTPLLYEEPE TSKTIRLNSY SSLRTSMNFS 790 800 810 820 830 840 EEVSLSVLEE KTRIQSDDVE NSETVIKDAL PSSASIGSFL HSLLEELDFS IFKTTTSKEL 850 860 870 880 890 900 LKNEKIISRM DFHLDYFRIL KREEGRPILE KETVQKRTVE ILWNLLNANI LDQKGALFRL 910 920 930 940 950 960 VDLPKENRVS EMDFYLDLDT NPGNFLRGSI DLVFQIDDKF YLADYKSNLL EDYSTISLKR 970 980 990 1000 1010 1020 NVENLESRYD LQRDIYALVL YEYLKNLFGP KEALQKIGGV YYFFLRGMIY GESSGIYSDF 1030 1040 FWSLERIESI RKTVLESTTF RWEKSN

References

[1]

"Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing." Ren S.-X., Fu G., Jiang X.-G., Zeng R., Miao Y.-G., Xu H., Zhang Y.-X., Xiong H., Lu G., Lu L.-F., Jiang H.-Q., Jia J., Tu Y.-F., Jiang J.-X., Gu W.-Y., Zhang Y.-Q., Cai Z., Sheng H.-H. , Yin H.-F., Zhang Y., Zhu G.-F., Wan M., Huang H.-L., Qian Z., Wang S.-Y., Ma W., Yao Z.-J., Shen Y., Qiang B.-Q., Xia Q.-C., Guo X.-K., Danchin A., Saint Girons I., Somerville R.L., Wen Y.-M., Shi M.-H., Chen Z., Xu J.-G., Zhao G.-P. Nature 422:888-893(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 56601.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE010300 Genomic DNA. Translation: AAN48165.1.
RefSeq	NP_711147.1. NC_004342.2.
3D structure databases
HSSP	HSSP built from PDB template 1PJR based on UniProtKB P56255.
ProteinModelPortal	Q8F7H9.
ModBase	Search...
Protein-protein interaction databases
STRING	189518.LA0966.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAN48165; AAN48165; LA_0966.
GeneID	1150309.
KEGG	lil:LA_0966.
PATRIC	22382783. VBILepInt91350_0968.
Phylogenomic databases
HOGENOM	HOG000041061.
KO	K03582.
OMA	EYDIVFC.
ProtClustDB	CLSK573724.
Enzyme and pathway databases
BioCyc	LINT189518:GJBB-781-MONOMER.
Family and domain databases
Gene3D	3.90.320.10. 1 hit.
InterPro	IPR014017. DNA_helicase_UvrD-like_C. IPR000212. DNA_helicase_UvrD/REP. IPR011604. Exonuc_phg/RecB_C. IPR011335. Restrct_endonuc-II-like. IPR014016. UvrD-like_ATP-bd. [Graphical view]
PANTHER	PTHR11070. PTHR11070. 1 hit.
Pfam	PF00580. UvrD-helicase. 1 hit. PF13361. UvrD_C. 1 hit. [Graphical view]
SUPFAM	SSF52980. Restrict_endonuc_II-like_core. 1 hit.
PROSITE	PS51198. UVRD_HELICASE_ATP_BIND. 1 hit. PS51217. UVRD_HELICASE_CTER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8F7H9_LEPIN

Accession

Primary (citable) accession number: Q8F7H9

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	May 1, 2013
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)