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Protein
Submitted name:

Adenylate/guanylate cyclase

Gene

cyaA

Organism
Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotation

Enzyme and pathway databases

BioCyciLINT189518:G1GL4-859-MONOMER

Names & Taxonomyi

Protein namesi
Submitted name:
Adenylate/guanylate cyclaseImported
Gene namesi
Name:cyaAImported
Ordered Locus Names:LA_1070Imported
OrganismiLeptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)Imported
Taxonomic identifieri189518 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesLeptospiralesLeptospiraceaeLeptospira
Proteomesi
  • UP000001408 Componenti: Chromosome I

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 31HelicalSequence analysisAdd BLAST20
Transmembranei37 – 55HelicalSequence analysisAdd BLAST19
Transmembranei62 – 80HelicalSequence analysisAdd BLAST19
Transmembranei100 – 117HelicalSequence analysisAdd BLAST18

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi189518.LA_1070

Structurei

3D structure databases

ProteinModelPortaliQ8F778
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini158 – 289Guanylate cyclaseInterPro annotationAdd BLAST132

Sequence similaritiesi

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG4108VSS Bacteria
COG2114 LUCA
HOGENOMiHOG000040263
KOiK01768
OMAiEFVEDIW

Family and domain databases

Gene3Di3.30.70.1230, 1 hit
InterProiView protein in InterPro
IPR001054 A/G_cyclase
IPR018297 A/G_cyclase_CS
IPR029787 Nucleotide_cyclase
PfamiView protein in Pfam
PF00211 Guanylate_cyc, 1 hit
SMARTiView protein in SMART
SM00044 CYCc, 1 hit
SUPFAMiSSF55073 SSF55073, 1 hit
PROSITEiView protein in PROSITE
PS00452 GUANYLATE_CYCLASE_1, 1 hit
PS50125 GUANYLATE_CYCLASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8F778-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYFISRIKSI YHSLFWPFNL IILIYLSWMW FFNGGSIGGN HYYFIPALVI
60 70 80 90 100
ATILLRKHNV WLVYLIYATS TAFLYGIEFF HRELVKSYSN DTERYLDAGG
110 120 130 140 150
NYLFVQILTG LLIFILTRNL NIERKKSDSL LLNILPESVA EELKRNDFVV
160 170 180 190 200
PIRYENVTVL FTDMAGFTKI AESMSPEELL SELDLFFREF DLITKKHGME
210 220 230 240 250
KIKTIGDSYM AAGGLPIVNN THSIDAVLCG LEFQKFMRLK KKERENNHLP
260 270 280 290 300
FWELRLGIHS GSVVAGVVGT KKFAYDIWGD SVNTASRMES SGIPGEVNIS
310 320 330 340 350
QETFEKIKDF FICDYRGKIK AKNKGEIDMY LVKKIREGLH DPEDELKPNQ
360
TFFKFYSQIQ NGELLS
Length:366
Mass (Da):42,315
Last modified:March 1, 2003 - v1
Checksum:iD41E6ACA5E8C36CF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE010300 Genomic DNA Translation: AAN48269.1
RefSeqiNP_711251.1, NC_004342.2
WP_011069661.1, NC_004342.2

Genome annotation databases

EnsemblBacteriaiAAN48269; AAN48269; LA_1070
GeneIDi1150413
KEGGilil:LA_1070
PATRICifig|189518.3.peg.1067

Similar proteinsi

Entry informationi

Entry nameiQ8F778_LEPIN
AccessioniPrimary (citable) accession number: Q8F778
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: March 28, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health