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Protein
Submitted name:

Adenylate/guanylate cyclase

Gene

cyaA

Organism
Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotation

Enzyme and pathway databases

BioCyciLINT189518:GJBB-863-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Adenylate/guanylate cyclaseImported
Gene namesi
Name:cyaAImported
Ordered Locus Names:LA_1070Imported
OrganismiLeptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)Imported
Taxonomic identifieri189518 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesLeptospiralesLeptospiraceaeLeptospira
ProteomesiUP000001408 Componenti: Chromosome I

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei12 – 3120HelicalSequence analysisAdd
BLAST
Transmembranei37 – 5519HelicalSequence analysisAdd
BLAST
Transmembranei62 – 8019HelicalSequence analysisAdd
BLAST
Transmembranei100 – 11718HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi189518.LA_1070.

Structurei

3D structure databases

ProteinModelPortaliQ8F778.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini158 – 289132Guanylate cyclaseInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiCOG2114. LUCA.
ENOG4108VSS. Bacteria.
HOGENOMiHOG000040263.
KOiK01768.
OMAiDSAREMR.
OrthoDBiEOG6C012M.

Family and domain databases

Gene3Di3.30.70.1230. 1 hit.
InterProiIPR001054. A/G_cyclase.
IPR018297. A/G_cyclase_CS.
IPR029787. Nucleotide_cyclase.
[Graphical view]
PfamiPF00211. Guanylate_cyc. 1 hit.
[Graphical view]
SMARTiSM00044. CYCc. 1 hit.
[Graphical view]
SUPFAMiSSF55073. SSF55073. 1 hit.
PROSITEiPS00452. GUANYLATE_CYCLASE_1. 1 hit.
PS50125. GUANYLATE_CYCLASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8F778-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYFISRIKSI YHSLFWPFNL IILIYLSWMW FFNGGSIGGN HYYFIPALVI
60 70 80 90 100
ATILLRKHNV WLVYLIYATS TAFLYGIEFF HRELVKSYSN DTERYLDAGG
110 120 130 140 150
NYLFVQILTG LLIFILTRNL NIERKKSDSL LLNILPESVA EELKRNDFVV
160 170 180 190 200
PIRYENVTVL FTDMAGFTKI AESMSPEELL SELDLFFREF DLITKKHGME
210 220 230 240 250
KIKTIGDSYM AAGGLPIVNN THSIDAVLCG LEFQKFMRLK KKERENNHLP
260 270 280 290 300
FWELRLGIHS GSVVAGVVGT KKFAYDIWGD SVNTASRMES SGIPGEVNIS
310 320 330 340 350
QETFEKIKDF FICDYRGKIK AKNKGEIDMY LVKKIREGLH DPEDELKPNQ
360
TFFKFYSQIQ NGELLS
Length:366
Mass (Da):42,315
Last modified:March 1, 2003 - v1
Checksum:iD41E6ACA5E8C36CF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE010300 Genomic DNA. Translation: AAN48269.1.
RefSeqiNP_711251.1. NC_004342.2.
WP_011069661.1. NC_004342.2.

Genome annotation databases

EnsemblBacteriaiAAN48269; AAN48269; LA_1070.
GeneIDi1150413.
KEGGilil:LA_1070.
PATRICi22382981. VBILepInt91350_1067.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE010300 Genomic DNA. Translation: AAN48269.1.
RefSeqiNP_711251.1. NC_004342.2.
WP_011069661.1. NC_004342.2.

3D structure databases

ProteinModelPortaliQ8F778.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi189518.LA_1070.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN48269; AAN48269; LA_1070.
GeneIDi1150413.
KEGGilil:LA_1070.
PATRICi22382981. VBILepInt91350_1067.

Phylogenomic databases

eggNOGiCOG2114. LUCA.
ENOG4108VSS. Bacteria.
HOGENOMiHOG000040263.
KOiK01768.
OMAiDSAREMR.
OrthoDBiEOG6C012M.

Enzyme and pathway databases

BioCyciLINT189518:GJBB-863-MONOMER.

Family and domain databases

Gene3Di3.30.70.1230. 1 hit.
InterProiIPR001054. A/G_cyclase.
IPR018297. A/G_cyclase_CS.
IPR029787. Nucleotide_cyclase.
[Graphical view]
PfamiPF00211. Guanylate_cyc. 1 hit.
[Graphical view]
SMARTiSM00044. CYCc. 1 hit.
[Graphical view]
SUPFAMiSSF55073. SSF55073. 1 hit.
PROSITEiPS00452. GUANYLATE_CYCLASE_1. 1 hit.
PS50125. GUANYLATE_CYCLASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 56601Imported.

Entry informationi

Entry nameiQ8F778_LEPIN
AccessioniPrimary (citable) accession number: Q8F778
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: December 9, 2015
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.