Q8F778 (Q8F778_LEPIN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Adenylate/guanylate cyclase EMBL AAN48269.1

Gene names

Name:	cyaA EMBL AAN48269.1
Ordered Locus Names:	LA_1070

Organism

Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601) [Reference proteome] [HAMAP] EMBL AAN48269.1

Taxonomic identifier

189518 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Spirochaetes › Spirochaetia › Spirochaetales › Leptospiraceae › Leptospira › Leptospira interrogans › Leptospira interrogans serovar Lai

Protein attributes

Sequence length	366 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. RuleBase RU000405

Ontologies

Keywords
Molecular function	Lyase RuleBase RU000405
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cyclic nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro intracellular signal transduction Inferred from electronic annotation. Source: InterPro
Molecular_function	phosphorus-oxygen lyase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8F778 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: D41E6ACA5E8C36CF	FASTA	366	42,315
	10 20 30 40 50 60 MYFISRIKSI YHSLFWPFNL IILIYLSWMW FFNGGSIGGN HYYFIPALVI ATILLRKHNV 70 80 90 100 110 120 WLVYLIYATS TAFLYGIEFF HRELVKSYSN DTERYLDAGG NYLFVQILTG LLIFILTRNL 130 140 150 160 170 180 NIERKKSDSL LLNILPESVA EELKRNDFVV PIRYENVTVL FTDMAGFTKI AESMSPEELL 190 200 210 220 230 240 SELDLFFREF DLITKKHGME KIKTIGDSYM AAGGLPIVNN THSIDAVLCG LEFQKFMRLK 250 260 270 280 290 300 KKERENNHLP FWELRLGIHS GSVVAGVVGT KKFAYDIWGD SVNTASRMES SGIPGEVNIS 310 320 330 340 350 360 QETFEKIKDF FICDYRGKIK AKNKGEIDMY LVKKIREGLH DPEDELKPNQ TFFKFYSQIQ NGELLS

References

[1]

"Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing." Ren S.-X., Fu G., Jiang X.-G., Zeng R., Miao Y.-G., Xu H., Zhang Y.-X., Xiong H., Lu G., Lu L.-F., Jiang H.-Q., Jia J., Tu Y.-F., Jiang J.-X., Gu W.-Y., Zhang Y.-Q., Cai Z., Sheng H.-H. , Yin H.-F., Zhang Y., Zhu G.-F., Wan M., Huang H.-L., Qian Z., Wang S.-Y., Ma W., Yao Z.-J., Shen Y., Qiang B.-Q., Xia Q.-C., Guo X.-K., Danchin A., Saint Girons I., Somerville R.L., Wen Y.-M., Shi M.-H., Chen Z., Xu J.-G., Zhao G.-P. Nature 422:888-893(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 56601.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE010300 Genomic DNA. Translation: AAN48269.1.
RefSeq	NP_711251.1. NC_004342.2.
3D structure databases
HSSP	HSSP built from PDB template 1CUL based on UniProtKB P26769.
ProteinModelPortal	Q8F778.
ModBase	Search...
Protein-protein interaction databases
STRING	189518.LA1070.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAN48269; AAN48269; LA_1070.
GeneID	1150413.
KEGG	lil:LA_1070.
PATRIC	22382981. VBILepInt91350_1067.
Phylogenomic databases
HOGENOM	HOG000040263.
KO	K01768.
OMA	NTHSIDA.
ProtClustDB	CLSK384340.
Enzyme and pathway databases
BioCyc	LINT189518:GJBB-863-MONOMER.
Family and domain databases
Gene3D	3.30.70.1230. 1 hit.
InterPro	IPR001054. A/G_cyclase. IPR018297. A/G_cyclase_CS. [Graphical view]
Pfam	PF00211. Guanylate_cyc. 1 hit. [Graphical view]
SMART	SM00044. CYCc. 1 hit. [Graphical view]
SUPFAM	SSF55073. A/G_cyclase. 1 hit.
PROSITE	PS00452. GUANYLATE_CYCLASE_1. 1 hit. PS50125. GUANYLATE_CYCLASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8F778_LEPIN

Accession

Primary (citable) accession number: Q8F778

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	May 1, 2013
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)