Unreviewed, UniProtKB/TrEMBL Q8F6W6 (Q8F6W6_LEPIN)

Names and origin

Protein names

Submitted name:
    Adenylate cyclase EMBL AAN48383.1
    EC=4.6.1.1

Gene names

Name:	cyaA6 EMBL AAN48383.1
Ordered Locus Names:	LA1184
ORF Names:	LA_1184 EMBL AAN48383.1

Organism

Leptospira interrogans [Complete proteome] [HAMAP]

Taxonomic identifier

173 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Leptospiraceae › Leptospira

Protein attributes

Sequence length	530 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Predicted.

Ontologies

Keywords
Ligand	Iron Iron-sulfur RuleBase RU000391V1 Metal-binding
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cyclic nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro intracellular signaling cascade Inferred from electronic annotation. Source: InterPro response to oxidative stress Inferred from electronic annotation. Source: InterPro
Molecular function	adenylate cyclase activity Inferred from electronic annotation. Source: EC electron carrier activity Inferred from electronic annotation. Source: InterPro heme binding Inferred from electronic annotation. Source: InterPro iron-sulfur cluster binding Inferred from electronic annotation. Source: InterPro peroxidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8F6W6-1 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: EBE31DDC08E45D10	FASTA	530	59,459
	10 20 30 40 50 60 MILVNFENEK EISLSKPQNL LEISLNNGIP HTHACGGNAR CSTCRVLVLE NPSHLSPPEQ 70 80 90 100 110 120 KEKELSQKKG FPKSVRLACQ TTVLGDVRVR RIVLDEEDYN LTIPGSATIS GEEKEIAILF 130 140 150 160 170 180 SDIRDFTLFS ESHLPYDVIH ILNRYFYKMG DVILKHGGKI DKYIGDGLMA LFGVNGGSPQ 190 200 210 220 230 240 EICISALRAA KEMELELYSL NEYLKSHLHT SFRIGVGVHY GNCILGQLGH PANMSYTAIG 250 260 270 280 290 300 DSVNIASRIE SKTKKSGASV LISESLYKQV KEKVVKGRVF SAQLKGKTGN YKLYEIQEIL 310 320 330 340 350 360 EKVDANLWEE AKNSLRRIIL VREVGSWLKL VYHLSCLFDE NQNWIGLSAA NSFQKFSKLP 370 380 390 400 410 420 ENGDLVQNFY QIKDTFNEQF QNSFSFADLL ALAGAVAIEK SGGPKIPIQP GRKDRLLSEV 430 440 450 460 470 480 FQILPLSMQT QKDQLPYLQK MKLGIRDIVL ISGARTIGWL GGESFTSNPY NFDNSYFHVL 490 500 510 520 530 LKAGLEGPLL IPNDRELLKN DESRAFVLDY ALDPSKFFED FTSTYLKLTS

References

[1]

"Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing." Ren S.-X., Fu G., Jiang X.-G., Zeng R., Miao Y.-G., Xu H., Zhang Y.-X., Xiong H., Lu G., Lu L.-F., Jiang H.-Q., Jia J., Tu Y.-F., Jiang J.-X., Gu W.-Y., Zhang Y.-Q., Cai Z., Sheng H.-H. , Yin H.-F., Zhang Y., Zhu G.-F., Wan M., Huang H.-L., Qian Z., Wang S.-Y., Ma W., Yao Z.-J., Shen Y., Qiang B.-Q., Xia Q.-C., Guo X.-K., Danchin A., Saint Girons I., Somerville R.L., Wen Y.-M., Shi M.-H., Chen Z., Xu J.-G., Zhao G.-P. Nature 422:888-893(2003) [PubMed: 12712204] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 56601 / Serogroup Icterohaemorrhagiae / Serovar lai.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE010300 Genomic DNA. Translation: AAN48383.1.
RefSeq	NP_711365.1.
3D structure databases
HSSP	HSSP built from PDB template 1OAF based on UniProtKB Q43758.
ModBase	Search...
Genome annotation databases
GeneID	1150527.
GenomeReviews	Gene locus LA1184 in contig AE010300_GR.
KEGG	lil:LA1184.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8F6W6.
Enzyme and pathway databases
BioCyc	LINT189518:LA1184-MON.
Family and domain databases
InterPro	IPR001054. A/G_cyclase. IPR002207. Asc_perxdse. IPR012675. b-grasp_ferredoxin-like. IPR001041. Ferredoxin. IPR002016. Haem_peroxidase_pln/fun/bac. [Graphical view]
Gene3D	G3DSA:3.30.70.1230. A/G_cyclase. 1 hit. G3DSA:3.10.20.30. Ferredoxin_fold. 1 hit.
Pfam	PF00111. Fer2. 1 hit. PF00211. Guanylate_cyc. 1 hit. PF00141. peroxidase. 2 hits. [Graphical view]
PRINTS	PR00459. ASPEROXIDASE. PR00458. PEROXIDASE.
SMART	SM00044. CYCc. 1 hit. [Graphical view]
PROSITE	PS51085. 2FE2S_FER_2. 1 hit. PS50125. GUANYLATE_CYCLASE_2. 1 hit. PS50873. PEROXIDASE_4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8F6W6_LEPIN

Accession

Primary (citable) accession number: Q8F6W6

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	June 16, 2009
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)