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Protein
Submitted name:

Serine/threonine kinase with GAF and PP2C domains

Gene

LA_1422

Organism
Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciLINT189518:GJBB-1130-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Serine/threonine kinase with GAF and PP2C domainsImported
Gene namesi
Ordered Locus Names:LA_1422Imported
OrganismiLeptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)Imported
Taxonomic identifieri189518 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesLeptospiralesLeptospiraceaeLeptospira
ProteomesiUP000001408 Componenti: Chromosome I

Interactioni

Protein-protein interaction databases

STRINGi189518.LA_1422.

Structurei

3D structure databases

ProteinModelPortaliQ8F687.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000263148.
InParanoidiQ8F687.
OMAiLLMIEYS.
OrthoDBiEOG6HTNS7.

Family and domain databases

Gene3Di1.25.40.10. 4 hits.
3.30.450.40. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003018. GAF.
IPR029016. GAF_dom-like.
IPR011009. Kinase-like_dom.
IPR027417. P-loop_NTPase.
IPR001932. PPM-type_phosphatase_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
IPR011990. TPR-like_helical_dom.
[Graphical view]
PfamiPF01590. GAF. 1 hit.
PF00069. Pkinase. 1 hit.
PF07228. SpoIIE. 1 hit.
[Graphical view]
SMARTiSM00065. GAF. 1 hit.
SM00331. PP2C_SIG. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF55781. SSF55781. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8F687-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIDGYEIKD RMNTDSSTEV YKAVRSKDKT EVVVKYIPIL DELHPAVVNL
60 70 80 90 100
RNEYEILSYL SSEKMIRAFG MEKIPEGFIL ILEFVPGQSL KHFSQKRPVN
110 120 130 140 150
LKDFFKIAID LAEKLGEIHN KKVIHKDLKP DNIIFNPDEN ILRIVDFGIS
160 170 180 190 200
TRLSKEESSW SNPNRLEGSI HYVSPEQTGR MNRSVDYRSD FYSLGITFYE
210 220 230 240 250
LLTGKLPFES EDLLELVHFH LAKSPVDPRK IRSEIPEALS HVILKLLSKT
260 270 280 290 300
AEERYQTSEG LKNDLEIIRD KWLESGDAPA FPLGSTDYSH EFKIPQKLYG
310 320 330 340 350
RESYIEALLN EFKRMTETGR PSIVLIAGYS GVGKSSLVKE INKPLTESKG
360 370 380 390 400
YSISGKFDQY NRNVPFSAII QVFSNLIEQI LTESPERIEE WKNKIRDTLG
410 420 430 440 450
ANGKVITDVL PELEFIIGEQ PPVTELGPQE NANRFYLVFQ NFIKIFANQD
460 470 480 490 500
HPLAIFLDDL QWADTPSLEL VKNLIEDASV NYLFLILAYR DNEVDSTHPF
510 520 530 540 550
SALISGLEKE GFRLDKILLK PLSLENVNEL LSDSLRRPTE ETMSFAEIVY
560 570 580 590 600
SKTRGNPFFI NELLKQLSKE EIISYQKGSP TDSGRWVWNL EKIKNTNISD
610 620 630 640 650
NVVELLVNRI KKLPPRTQET LKLASCIGSN FDLAIQAKIL GATLKETAEA
660 670 680 690 700
LMETMQEELI VPIGDNYRLV DSMVEIEKNQ DKNFQIAKSI QFRFQHDRVQ
710 720 730 740 750
QASYELLNDD QKQSLRLQIG RILLENLNEK TLEDSIFDVV NHLNTGSTLI
760 770 780 790 800
TDNSEKRKLL QLNLQAAQKA KLSAAYKPSK LYCLQAKELL SSLCKSEKDC
810 820 830 840 850
WNQEYDLSYA VHKELAEVLY LNGDFEESQE TIQDILKQAK TPVEQAEAYN
860 870 880 890 900
LLMIEYSAQG KYDLAMPTVI KALKPLGIEL PTSGFDKVVK KELEEAKKNL
910 920 930 940 950
KNRSITSLLD APTMTDPSHI WAVNLLISAI PMAYNKEPAL FPVICLKMAN
960 970 980 990 1000
LLLKFGNLSD SYGYSCYGMV LVGQGDYKGA YDFCELAVKL SEKYINSGGY
1010 1020 1030 1040 1050
TKAANILANY SSSFVKHLKF SEEINIKCVQ SALDSGEFLH GSYAAMNDAS
1060 1070 1080 1090 1100
NVLFQGKNLE ILKPKINELL KFVRKVKNNL AIDTILGTTL ILSNLRGETG
1110 1120 1130 1140 1150
SHLDFSSTEY LEKEYIDLCN DHQSLAPICT FKVMKVRSLL MYGEYQLALQ
1160 1170 1180 1190 1200
EAEETNGMIL YLGGQYGPFE YNFLYSLALA ANYKKVSPDR KKESVKKIRE
1210 1220 1230 1240 1250
NQKQLLVLAE SCPENFYHKY LLVEAELARL EYKNWKAART YEAAIREARK
1260 1270 1280 1290 1300
NEFQNDEALA CENAALFWLS KGSVKIAGEF INEAYHRYGL WGANLKQSML
1310 1320 1330 1340 1350
KSKYPEFIRE RGTGLLRTHR TISSTTSTAT EIYSGQTLDL QSVLKSSTAI
1360 1370 1380 1390 1400
LGEIKLENLL DKLMKIVIEN AGAQRGVLIL KKEGKLYVEA EGSISKDDVE
1410 1420 1430 1440 1450
VLTGIPLGSS KNLPISLIYY VERTKENLVL RNASQDEKFN KDEYIKNFKT
1460 1470 1480 1490 1500
KSILCTPVIK QGEISGILYL ENNLSEGAFT SDRLQIMNIL SSQAAISIDN
1510 1520 1530 1540 1550
ALLYSNMEEK VRERTRELAQ ANADLELKNQ RITDSITYSL NIQQAILPSD
1560 1570 1580 1590 1600
DILAKNLKDQ FVLFRPKDIV SGDFYWFSKK EGSIFLAAVD CTGHGVPGAL
1610 1620 1630 1640 1650
MSMIGNTLLN QIVNEAGIKD PGKVLEHLNK NVRQALKQDT LGANSSDGMD
1660 1670 1680 1690 1700
ICFCRIDEDK VLFAGAKRPL YFSKGNHIEE IKGDKHSIGG RQKEVSRTYS
1710 1720 1730 1740 1750
THEVKLEKGQ SAMFYLTTDG FMDQPNPQRQ RITSKGLIAR LQNVLSLPAY
1760 1770 1780
EQKNQLAAFL DEYQAGEAQR DDITLIGFRV
Length:1,780
Mass (Da):201,610
Last modified:March 1, 2003 - v1
Checksum:iEC588AC9E8DFC4C5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE010300 Genomic DNA. Translation: AAN48621.1.
RefSeqiNP_711603.1. NC_004342.2.
WP_000686845.1. NC_004342.2.

Genome annotation databases

EnsemblBacteriaiAAN48621; AAN48621; LA_1422.
GeneIDi1150765.
KEGGilil:LA_1422.
PATRICi22383685. VBILepInt91350_1416.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE010300 Genomic DNA. Translation: AAN48621.1.
RefSeqiNP_711603.1. NC_004342.2.
WP_000686845.1. NC_004342.2.

3D structure databases

ProteinModelPortaliQ8F687.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi189518.LA_1422.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN48621; AAN48621; LA_1422.
GeneIDi1150765.
KEGGilil:LA_1422.
PATRICi22383685. VBILepInt91350_1416.

Phylogenomic databases

HOGENOMiHOG000263148.
InParanoidiQ8F687.
OMAiLLMIEYS.
OrthoDBiEOG6HTNS7.

Enzyme and pathway databases

BioCyciLINT189518:GJBB-1130-MONOMER.

Family and domain databases

Gene3Di1.25.40.10. 4 hits.
3.30.450.40. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003018. GAF.
IPR029016. GAF_dom-like.
IPR011009. Kinase-like_dom.
IPR027417. P-loop_NTPase.
IPR001932. PPM-type_phosphatase_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
IPR011990. TPR-like_helical_dom.
[Graphical view]
PfamiPF01590. GAF. 1 hit.
PF00069. Pkinase. 1 hit.
PF07228. SpoIIE. 1 hit.
[Graphical view]
SMARTiSM00065. GAF. 1 hit.
SM00331. PP2C_SIG. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF55781. SSF55781. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 56601Imported.

Entry informationi

Entry nameiQ8F687_LEPIN
AccessioniPrimary (citable) accession number: Q8F687
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: July 22, 2015
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.