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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciLINT189518:G1GL4-1357-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:LA_1688
OrganismiLeptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Taxonomic identifieri189518 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesLeptospiralesLeptospiraceaeLeptospira
Proteomesi
  • UP000001408 Componenti: Chromosome I

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001515711 – 586Arginine--tRNA ligaseAdd BLAST586

Proteomic databases

PRIDEiQ8F5J3

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi189518.LA_1688

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi133 – 143"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247214
InParanoidiQ8F5J3
KOiK01887

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit

Sequencei

Sequence statusi: Complete.

Q8F5J3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKENETLKQI VLKTLEESVN SLISSFPEVE KETFKIKIEY SRDEKFGDYS
60 70 80 90 100
TSFALENSKL LKRNPIQVSK ELVEILQKRT DLFEKVDFTP PGFVNFRIST
110 120 130 140 150
SFLLNYIETS VLSGNYFPKV DLPLKINLEF VSANPTGPLN IVSARAAANG
160 170 180 190 200
DTMASLLKAI GHNVDKEFYI NDYGNQVFLL GVSTLVRIRE LKGEEGTQQE
210 220 230 240 250
TTDDTPIEII LEKNILPAEG YRGEYIKDIA SSLLKDPKKN VTIENLLKQK
260 270 280 290 300
KYKELAELCA VWTIENNLIW QRKDLDAFGV EFDRYFSERT LHEADKVLSV
310 320 330 340 350
MKDLEKSGKI FQEDGKKVFR STEYGDDKDR VVVRDDGRPT YLLADIAYHK
360 370 380 390 400
DKIERGYDKI YDIWGPDHHG YISRLSGAVQ SLGYKKENFK VIISQQVNLL
410 420 430 440 450
ESGQKVKMSK RAGSFQTMSD LIGFLGKHGK DVGRYFFVMR SLDAPLDFDL
460 470 480 490 500
DLAKDESDKN PVFYLQYAHA RICSIFKEVG DQTSKEATAI LEMSEERKRL
510 520 530 540 550
LFWIARFPEE IFDSANAMEP HRVTNYLQSF AKAFTSFYLA KDNRLKDASK
560 570 580
EVRLGLARIC LAAKNVLAEG LKLIGVSAPE RMEKEN
Length:586
Mass (Da):66,934
Last modified:August 10, 2010 - v2
Checksum:i1E1076F05F07E695
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE010300 Genomic DNA Translation: AAN48887.2
RefSeqiNP_711869.2, NC_004342.2
WP_000662007.1, NC_004342.2

Genome annotation databases

EnsemblBacteriaiAAN48887; AAN48887; LA_1688
GeneIDi1151031
KEGGilil:LA_1688
PATRICifig|189518.3.peg.1681

Similar proteinsi

Entry informationi

Entry nameiSYR_LEPIN
AccessioniPrimary (citable) accession number: Q8F5J3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: August 10, 2010
Last modified: May 23, 2018
This is version 88 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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