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Q8F5J3

- SYR_LEPIN

UniProt

Q8F5J3 - SYR_LEPIN

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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

  1. arginine-tRNA ligase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciLINT189518:GJBB-1362-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:LA_1688
OrganismiLeptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Taxonomic identifieri189518 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesLeptospiraceaeLeptospira
ProteomesiUP000001408: Chromosome I

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 586586Arginine--tRNA ligasePRO_0000151571Add
BLAST

Proteomic databases

PaxDbiQ8F5J3.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi189518.LA1688.

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi133 – 14311"HIGH" regionAdd
BLAST

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0018.
HOGENOMiHOG000247214.
InParanoidiQ8F5J3.
KOiK01887.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8F5J3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKENETLKQI VLKTLEESVN SLISSFPEVE KETFKIKIEY SRDEKFGDYS
60 70 80 90 100
TSFALENSKL LKRNPIQVSK ELVEILQKRT DLFEKVDFTP PGFVNFRIST
110 120 130 140 150
SFLLNYIETS VLSGNYFPKV DLPLKINLEF VSANPTGPLN IVSARAAANG
160 170 180 190 200
DTMASLLKAI GHNVDKEFYI NDYGNQVFLL GVSTLVRIRE LKGEEGTQQE
210 220 230 240 250
TTDDTPIEII LEKNILPAEG YRGEYIKDIA SSLLKDPKKN VTIENLLKQK
260 270 280 290 300
KYKELAELCA VWTIENNLIW QRKDLDAFGV EFDRYFSERT LHEADKVLSV
310 320 330 340 350
MKDLEKSGKI FQEDGKKVFR STEYGDDKDR VVVRDDGRPT YLLADIAYHK
360 370 380 390 400
DKIERGYDKI YDIWGPDHHG YISRLSGAVQ SLGYKKENFK VIISQQVNLL
410 420 430 440 450
ESGQKVKMSK RAGSFQTMSD LIGFLGKHGK DVGRYFFVMR SLDAPLDFDL
460 470 480 490 500
DLAKDESDKN PVFYLQYAHA RICSIFKEVG DQTSKEATAI LEMSEERKRL
510 520 530 540 550
LFWIARFPEE IFDSANAMEP HRVTNYLQSF AKAFTSFYLA KDNRLKDASK
560 570 580
EVRLGLARIC LAAKNVLAEG LKLIGVSAPE RMEKEN
Length:586
Mass (Da):66,934
Last modified:August 10, 2010 - v2
Checksum:i1E1076F05F07E695
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE010300 Genomic DNA. Translation: AAN48887.2.
RefSeqiNP_711869.2. NC_004342.2.

Genome annotation databases

EnsemblBacteriaiAAN48887; AAN48887; LA_1688.
GeneIDi1151031.
KEGGilil:LA_1688.
PATRICi22384214. VBILepInt91350_1681.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE010300 Genomic DNA. Translation: AAN48887.2 .
RefSeqi NP_711869.2. NC_004342.2.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 189518.LA1688.

Proteomic databases

PaxDbi Q8F5J3.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAN48887 ; AAN48887 ; LA_1688 .
GeneIDi 1151031.
KEGGi lil:LA_1688.
PATRICi 22384214. VBILepInt91350_1681.

Phylogenomic databases

eggNOGi COG0018.
HOGENOMi HOG000247214.
InParanoidi Q8F5J3.
KOi K01887.

Enzyme and pathway databases

BioCyci LINT189518:GJBB-1362-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPi MF_00123. Arg_tRNA_synth.
InterProi IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view ]
PANTHERi PTHR11956. PTHR11956. 1 hit.
Pfami PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view ]
PRINTSi PR01038. TRNASYNTHARG.
SMARTi SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view ]
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsi TIGR00456. argS. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 56601.

Entry informationi

Entry nameiSYR_LEPIN
AccessioniPrimary (citable) accession number: Q8F5J3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: August 10, 2010
Last modified: October 29, 2014
This is version 72 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3