Q8F5D8 (CHEB2_LEPIN) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 53.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Putative chemotaxis protein-glutamate methylesterase EC=3.1.1.61 | ||||
| Gene names |
| ||||
| Organism | Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601) | ||||
| Taxonomic identifier | 189518 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Spirochaetes › Spirochaetales › Leptospiraceae › Leptospira |
Protein attributes
| Sequence length | 193 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | May be involved in the modulation of the chemotaxis system By similarity. HAMAP MF_00099 |
| Catalytic activity | Protein L-glutamate O(5)-methyl ester + H2O = protein L-glutamate + methanol. HAMAP MF_00099 |
| Subcellular location | Cytoplasm By similarity HAMAP MF_00099. |
| Sequence similarities | Contains 1 cheB-type methylesterase domain. |
| Sequence caution | The sequence AAN48943.2 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Chemotaxis |
| Cellular component | Cytoplasm |
| Molecular function | Hydrolase |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | chemotaxis Inferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | protein-glutamate methylesterase activity Inferred from electronic annotation. Source: EC two-component response regulator activityInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 193 | 193 | Putative chemotaxis protein-glutamate methylesterase HAMAP MF_00099 | PRO_0000158003 | |||||
Regions | |||||||||
| Domain | 1 – 193 | 193 | CheB-type methylesterase | ||||||
Sites | |||||||||
| Active site | 11 | 1 | By similarity | ||||||
| Active site | 38 | 1 | By similarity | ||||||
| Active site | 131 | 1 | By similarity | ||||||
Sequences
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References
| [1] | "Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing." Ren S.-X., Fu G., Jiang X.-G., Zeng R., Miao Y.-G., Xu H., Zhang Y.-X., Xiong H., Lu G., Lu L.-F., Jiang H.-Q., Jia J., Tu Y.-F., Jiang J.-X., Gu W.-Y., Zhang Y.-Q., Cai Z., Sheng H.-H. Zhao G.-P.Nature 422:888-893(2003) [PubMed: 12712204] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 56601. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AE010300 Genomic DNA. Translation: AAN48943.2. Different initiation. |
| RefSeq | NP_711925.2. NC_004342.2. |
3D structure databases | |
| ProteinModelPortal | Q8F5D8. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 1151087. |
| GenomeReviews | Gene locus LA_1744 in contig AE010300_GR. |
| KEGG | lil:LA_1744. |
| PATRIC | 22384322. VBILepInt91350_1735. |
Phylogenomic databases | |
| HOGENOM | HBG705324. |
| OMA | FAPPDYH. |
| PhylomeDB | Q8F5D8. |
| ProtClustDB | CLSK2298022. |
Enzyme and pathway databases | |
| BioCyc | LINT189518:LA1744-MONOMER. |
Family and domain databases | |
| HAMAP | MF_00099. CheB_methylest. Divergent sequence. [Tree] |
| InterPro | IPR000673. Sig_transdc_resp-reg_Me-estase. [Graphical view] |
| Gene3D | G3DSA:3.40.50.180. Chemotax_RR_pGlu_Me-esterase. 1 hit. |
| KO | K03412. |
| Pfam | PF01339. CheB_methylest. 1 hit. [Graphical view] |
| SUPFAM | SSF52738. Chemotax_RR_pGlu_Me-esterase. 1 hit. |
| PROSITE | PS50122. CHEB. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | CHEB2_LEPIN | ||||||||
| Accession | Primary (citable) accession number: Q8F5D8 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |

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