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Q8F495

- TRPF_LEPIN

UniProt

Q8F495 - TRPF_LEPIN

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Protein
N-(5'-phosphoribosyl)anthranilate isomerase
Gene
trpF, LA_2147
Organism
Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciLINT189518:GJBB-1741-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase (EC:5.3.1.24)
Short name:
PRAI
Gene namesi
Name:trpF
Ordered Locus Names:LA_2147
OrganismiLeptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Taxonomic identifieri189518 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesLeptospiraceaeLeptospira
ProteomesiUP000001408: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 213213N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotation
PRO_0000154362Add
BLAST

Proteomic databases

PaxDbiQ8F495.

Interactioni

Protein-protein interaction databases

STRINGi189518.LA2147.

Structurei

3D structure databases

ProteinModelPortaliQ8F495.

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.

Phylogenomic databases

eggNOGiCOG0135.
HOGENOMiHOG000161598.
KOiK01817.
OMAiNNARPIS.
OrthoDBiEOG6N94DF.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8F495-1 [UniParc]FASTAAdd to Basket

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MITNSLQKTK VKICGIKDLE IAKICKEEGA DYIGFNFVSS SPRKIELSNA    50
QKIVEYYKSE KNSPEIVLLF YQNSFEEIES ITSVLDHDLV QWVWDDPLIN 100
RKKLLYKRQI CSYRVQTQIH DQDLKDIEAE FLILDSYSKG VGGGTGETFN 150
WELISKVKRK FLLAGGLDPS NVVNAIEIVK PFGVDVASGV ESSPGIKDPQ 200
KVIQFIRNVK STS 213
Length:213
Mass (Da):24,066
Last modified:March 25, 2003 - v2
Checksum:iAFA2F32647276991
GO

Sequence cautioni

The sequence AAN49346.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE010300 Genomic DNA. Translation: AAN49346.1. Different initiation.
RefSeqiNP_712328.1. NC_004342.2.

Genome annotation databases

EnsemblBacteriaiAAN49346; AAN49346; LA_2147.
GeneIDi1151490.
KEGGilil:LA_2147.
PATRICi22385141. VBILepInt91350_2139.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE010300 Genomic DNA. Translation: AAN49346.1 . Different initiation.
RefSeqi NP_712328.1. NC_004342.2.

3D structure databases

ProteinModelPortali Q8F495.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 189518.LA2147.

Proteomic databases

PaxDbi Q8F495.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAN49346 ; AAN49346 ; LA_2147 .
GeneIDi 1151490.
KEGGi lil:LA_2147.
PATRICi 22385141. VBILepInt91350_2139.

Phylogenomic databases

eggNOGi COG0135.
HOGENOMi HOG000161598.
KOi K01817.
OMAi NNARPIS.
OrthoDBi EOG6N94DF.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .
BioCyci LINT189518:GJBB-1741-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 56601.

Entry informationi

Entry nameiTRPF_LEPIN
AccessioniPrimary (citable) accession number: Q8F495
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 25, 2003
Last sequence update: March 25, 2003
Last modified: May 14, 2014
This is version 66 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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