Unreviewed, UniProtKB/TrEMBL Q8F375 (Q8F375_LEPIN)

Names and origin

Protein names

Submitted name:
    Adenylate cyclase EMBL AAN49735.1
    EC=4.6.1.1

Gene names

Name:	cyaA8 EMBL AAN49735.1
Ordered Locus Names:	LA2536
ORF Names:	LA_2536 EMBL AAN49735.1

Organism

Leptospira interrogans [Complete proteome] [HAMAP]

Taxonomic identifier

173 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Leptospiraceae › Leptospira

Protein attributes

Sequence length	960 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Predicted.

Ontologies

Keywords
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cyclic nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro intracellular signaling cascade Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: InterPro
Molecular function	adenylate cyclase activity Inferred from electronic annotation. Source: EC signal transducer activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8F375-1 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: F1B47C2946652C25	FASTA	960	106,661
	10 20 30 40 50 60 MLEIHRRYLP FGTSGALIFI SDSYTNFSND LSEEISKKEI GTVCFVSSKI DSNAPDSIPT 70 80 90 100 110 120 SVNVLSLLIP PGPETNDSVY SSFLQIQKFL KRGNILFLIA SDCETRFPLL LSKLLLASSP 130 140 150 160 170 180 SLSDSELQNQ ISHLGYSYSE PDQTSFRKYI SRHKSLHSIP EIPPGEFSVS IHIARESKRP 190 200 210 220 230 240 STLKYKIKYE PGAENLTQIK AVPYSEEENK KSPSSFQSFP IDAIEIDHLE DTQKLKEFSV 250 260 270 280 290 300 SGESEEPTTT PSSESNHVSL SSESKLELST TETEILSTNS QTSENILTPQ IESIQTENKP 310 320 330 340 350 360 AQEIQLKPQT ESISNTEPIS TSSKIDKNTL DETKTNSPSS ATTQELSTSQ VKSKFPLQIK 370 380 390 400 410 420 LMAVISILMT FTVSTIIFFA SSAFRDDSEV RVLQNNLNLV NILGLKIKTD IKEILTNGKQ 430 440 450 460 470 480 MVGALVQGKQ GISFADIFFQ NDPDFIYAGL FQMEGNIPTM VNEFFNEPYL SELKVSSKEI 490 500 510 520 530 540 SDLVRNRPGL IQKSVLTGGR MENLSAEFKE PILAIAIPSS GSNSKILVLV LRLEKFLNAF 550 560 570 580 590 600 QKQDISEIFL VNGEGDLIAH SDPKLLQSNT NFMNLPIVES MVKSSENTKQ IEYKDKDGNA 610 620 630 640 650 660 WFGSYQKLGF GGAAVVSIVP ENKAFEAVYK IQKTNLLIMG IALCLALIIV FFFAKTITKP 670 680 690 700 710 720 VLNLLRATTE IAQGNFKIKI SSITNDEVGL LTDYFVDMSK GLEEREKVKD ALGRFVNKEI 730 740 750 760 770 780 AEMVLKHELT LGGERKMCAI FFSDIRSFTS ISEKLQPEEV VEFLNEYMTE MVHCVNETHG 790 800 810 820 830 840 IVDKFIGDAI MATWGAAKTS DRDAENAVNG ALMMREALIK FNQGRGGEKK PIIQIGCGLN 850 860 870 880 890 900 FGPVIAGQIG SEQRLEYTVI GDAVNLASRV EALNKPFGTD ILITQDLLDH VSEIFNVQKM 910 920 930 940 950 960 QSIKVKGKEE PQVIYAVLGR KDDPNCPKSL EELRERVGIV WEPPKKGSDS EKEVKYEILD

References

[1]

"Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing." Ren S.-X., Fu G., Jiang X.-G., Zeng R., Miao Y.-G., Xu H., Zhang Y.-X., Xiong H., Lu G., Lu L.-F., Jiang H.-Q., Jia J., Tu Y.-F., Jiang J.-X., Gu W.-Y., Zhang Y.-Q., Cai Z., Sheng H.-H. , Yin H.-F., Zhang Y., Zhu G.-F., Wan M., Huang H.-L., Qian Z., Wang S.-Y., Ma W., Yao Z.-J., Shen Y., Qiang B.-Q., Xia Q.-C., Guo X.-K., Danchin A., Saint Girons I., Somerville R.L., Wen Y.-M., Shi M.-H., Chen Z., Xu J.-G., Zhao G.-P. Nature 422:888-893(2003) [PubMed: 12712204] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 56601 / Serogroup Icterohaemorrhagiae / Serovar lai.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE010300 Genomic DNA. Translation: AAN49735.1.
RefSeq	NP_712717.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1151879.
GenomeReviews	Gene locus LA2536 in contig AE010300_GR.
KEGG	lil:LA2536.
NMPDR	fig|189518.1.peg.2536.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8F375.
OMA	Q8F375. EHSQIIN.
Enzyme and pathway databases
BioCyc	LINT189518:LA2536-MON.
Family and domain databases
InterPro	IPR001054. A/G_cyclase. IPR003660. HAMP_linker_domain. [Graphical view]
Gene3D	G3DSA:3.30.70.1230. A/G_cyclase. 1 hit.
Pfam	PF00211. Guanylate_cyc. 1 hit. PF00672. HAMP. 1 hit. [Graphical view]
SMART	SM00044. CYCc. 1 hit. SM00304. HAMP. 1 hit. [Graphical view]
PROSITE	PS50125. GUANYLATE_CYCLASE_2. 1 hit. PS50885. HAMP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8F375_LEPIN

Accession

Primary (citable) accession number: Q8F375

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	June 16, 2009
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)