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Protein
Submitted name:

Glutathione transferase

Gene

gst

Organism
Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei100 – 1001GlutathioneCombined sources

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

TransferaseImported

Enzyme and pathway databases

BioCyciLINT189518:GJBB-2141-MONOMER.

Protein family/group databases

TCDBi1.A.12.2.2. the intracellular chloride channel (clic) family.

Names & Taxonomyi

Protein namesi
Submitted name:
Glutathione transferaseImported
Gene namesi
Name:gstImported
Ordered Locus Names:LA_2623Imported
OrganismiLeptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)Imported
Taxonomic identifieri189518 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesLeptospiralesLeptospiraceaeLeptospira
Proteomesi
  • UP000001408 Componenti: Chromosome I

Interactioni

Protein-protein interaction databases

STRINGi189518.LA_2623.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3UBKX-ray1.95A/B1-218[»]
3UBLX-ray2.00A/B1-218[»]
ProteinModelPortaliQ8F2Y8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 7777GST N-terminalInterPro annotationAdd
BLAST
Domaini83 – 217135GST C-terminalInterPro annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni10 – 123Glutathione bindingCombined sources
Regioni48 – 492Glutathione bindingCombined sources
Regioni61 – 622Glutathione bindingCombined sources

Phylogenomic databases

eggNOGiENOG4105IU3. Bacteria.
ENOG4111R46. LUCA.
HOGENOMiHOG000125743.
KOiK00799.
OMAiSNYYNMV.
OrthoDBiEOG6TN453.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF13417. GST_N_3. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8F2Y8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKLHGASIS NYVNKVKLGI LEKGLEYEQI RIAPSQEEDF LKISPMGKIP
60 70 80 90 100
VLEMDGKFIF ESGAILEFLD TIFPQTPKLI PEDPWEAARV REISTIIETY
110 120 130 140 150
LDIPARRIYL PAAKVSPEIV EEVHSTLVKG IKALQRVVRF SPYIAGNVFT
160 170 180 190 200
LADCSGFAHL SVLDEELRPF YPNNHPLDLL NGWKEYFVFM KTKAGPALVE
210
KDKQILKKIL ARAKTKIG
Length:218
Mass (Da):24,637
Last modified:March 1, 2003 - v1
Checksum:i9C0C90187628DF57
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE010300 Genomic DNA. Translation: AAN49822.1.
RefSeqiNP_712804.1. NC_004342.2.
WP_000593328.1. NC_004342.2.

Genome annotation databases

EnsemblBacteriaiAAN49822; AAN49822; LA_2623.
GeneIDi1151966.
KEGGilil:LA_2623.
PATRICi22386079. VBILepInt91350_2605.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE010300 Genomic DNA. Translation: AAN49822.1.
RefSeqiNP_712804.1. NC_004342.2.
WP_000593328.1. NC_004342.2.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3UBKX-ray1.95A/B1-218[»]
3UBLX-ray2.00A/B1-218[»]
ProteinModelPortaliQ8F2Y8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi189518.LA_2623.

Protein family/group databases

TCDBi1.A.12.2.2. the intracellular chloride channel (clic) family.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN49822; AAN49822; LA_2623.
GeneIDi1151966.
KEGGilil:LA_2623.
PATRICi22386079. VBILepInt91350_2605.

Phylogenomic databases

eggNOGiENOG4105IU3. Bacteria.
ENOG4111R46. LUCA.
HOGENOMiHOG000125743.
KOiK00799.
OMAiSNYYNMV.
OrthoDBiEOG6TN453.

Enzyme and pathway databases

BioCyciLINT189518:GJBB-2141-MONOMER.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF13417. GST_N_3. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 56601Imported.
  2. "Crystal Structure of Glutathione S-Transferase from Leptospira Interrogans."
    Patskovsky Y., Toro R., Bhosle R., Zencheck W.D., Hillerich B., Seidel R.D., Washington E., Scott Glenn A., Chowdhury S., Evans B., Hammonds J., Imker H.J., Armstrong R.N., Gerlt J.A., Almo S.C.
    Submitted (OCT-2011) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.95 ANGSTROMS), X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) IN COMPLEX WITH GLUTATHIONE.

Entry informationi

Entry nameiQ8F2Y8_LEPIN
AccessioniPrimary (citable) accession number: Q8F2Y8
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: March 16, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.