ID   Q8F2U2_LEPIN            Unreviewed;       762 AA.
AC   Q8F2U2;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   27-MAR-2024, entry version 96.
DE   RecName: Full=Stage II sporulation protein E {ECO:0008006|Google:ProtNLM};
GN   OrderedLocusNames=LA_2676 {ECO:0000313|EMBL:AAN49875.1};
OS   Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain
OS   56601).
OC   Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC   Leptospira.
OX   NCBI_TaxID=189518 {ECO:0000313|EMBL:AAN49875.1, ECO:0000313|Proteomes:UP000001408};
RN   [1] {ECO:0000313|EMBL:AAN49875.1, ECO:0000313|Proteomes:UP000001408}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=56601 {ECO:0000313|EMBL:AAN49875.1,
RC   ECO:0000313|Proteomes:UP000001408};
RX   PubMed=12712204; DOI=10.1038/nature01597;
RA   Ren S.X., Fu G., Jiang X.G., Zeng R., Miao Y.G., Xu H., Zhang Y.X.,
RA   Xiong H., Lu G., Lu L.F., Jiang H.Q., Jia J., Tu Y.F., Jiang J.X., Gu W.Y.,
RA   Zhang Y.Q., Cai Z., Sheng H.H., Yin H.F., Zhang Y., Zhu G.F., Wan M.,
RA   Huang H.L., Qian Z., Wang S.Y., Ma W., Yao Z.J., Shen Y., Qiang B.Q.,
RA   Xia Q.C., Guo X.K., Danchin A., Saint Girons I., Somerville R.L., Wen Y.M.,
RA   Shi M.H., Chen Z., Xu J.G., Zhao G.P.;
RT   "Unique physiological and pathogenic features of Leptospira interrogans
RT   revealed by whole-genome sequencing.";
RL   Nature 422:888-893(2003).
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DR   EMBL; AE010300; AAN49875.1; -; Genomic_DNA.
DR   RefSeq; NP_712857.1; NC_004342.2.
DR   RefSeq; WP_000464922.1; NC_004342.2.
DR   AlphaFoldDB; Q8F2U2; -.
DR   STRING; 189518.LA_2676; -.
DR   PaxDb; 189518-LA_2676; -.
DR   EnsemblBacteria; AAN49875; AAN49875; LA_2676.
DR   KEGG; lil:LA_2676; -.
DR   PATRIC; fig|189518.3.peg.2657; -.
DR   HOGENOM; CLU_017260_0_0_12; -.
DR   InParanoid; Q8F2U2; -.
DR   OrthoDB; 343086at2; -.
DR   Proteomes; UP000001408; Chromosome I.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR011623; 7TMR_DISM_rcpt_extracell_dom1.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   Pfam; PF07695; 7TMR-DISM_7TM; 1.
DR   Pfam; PF07228; SpoIIE; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001408};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        259..281
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        288..304
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        324..342
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        349..367
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        379..396
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        408..427
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        433..454
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          259..455
FT                   /note="7TM-DISM receptor extracellular"
FT                   /evidence="ECO:0000259|Pfam:PF07695"
FT   DOMAIN          557..752
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|Pfam:PF07228"
SQ   SEQUENCE   762 AA;  88143 MW;  D34DCAD1D51135E7 CRC64;
     MFFGLENCFF ILIKESQKIK LKKIQYSFLR FVKMKDNKLW LLKSFSIVSF FAKMFSNFYR
     MFFGVLSKHF LFYFLIIFSV SSESIQKIQS LDEIVSLDST KEHGWEITLQ KIDPVAFSDS
     YLKGQKNSNI QLEAYEAPGV YILPEESIQT AFIVKKFIAP KNWKGSGLAV RLGTLTDKDK
     TYLNGTLIGE TGDMNSTLPQ AYDKIRIYQI PNGLIRKDEV NILVIEVKKY FQKEIGIEQD
     KTAIGDSLLI QKELLETEYI KILLLMIYTT AGVYFLFLYL RRRADRENLY YGLFTILLVL
     YQFLRNQIKY DLGIEFIYMK KLEYMVLATL VPLFANFIRL YFKYPKTTIL KVLDGLYVSF
     AIFYFFSNNV EHYNFINKNL VQYGWILYLG ITLNHLIRRV IAKDRDAFLI LIGVLITVFA
     AILDTLGARN VFVFPRLVGY SFLFFILSIA TILANKFVRL NEEVEELNLG LEKKVEQRTE
     ELRLSLEQVN RLKVQQDADY FLTSLLINPL SSNKNTSEVI KTEFYTKQKK SFEFKNRTYE
     IGGDILISGN VKLCGKKYVV FVNGDAMGKS IQGAGGALVL GTVFNTILTR SSISLYQNKQ
     PEKWLEEAFL ELQKIFESFD GSMYISIVLG LVEENTGLLY YINAEHPWTV LYRNGVACYI
     EEELTLRKIG IPENEEHLVI KNFQMLPGDT IVIGSDGRDD LLVGKEGNRV VNEDQNQFLK
     RVEEGNADLR KVYEEIIKFG VILDDLSLLK VTYNPEDSKT KE
//