ID   Q8F256_LEPIN            Unreviewed;       369 AA.
AC   Q8F256;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   27-MAR-2024, entry version 112.
DE   SubName: Full=Two-component response regulator {ECO:0000313|EMBL:AAN50119.1};
GN   OrderedLocusNames=LA_2921 {ECO:0000313|EMBL:AAN50119.1};
OS   Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain
OS   56601).
OC   Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC   Leptospira.
OX   NCBI_TaxID=189518 {ECO:0000313|EMBL:AAN50119.1, ECO:0000313|Proteomes:UP000001408};
RN   [1] {ECO:0000313|EMBL:AAN50119.1, ECO:0000313|Proteomes:UP000001408}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=56601 {ECO:0000313|EMBL:AAN50119.1,
RC   ECO:0000313|Proteomes:UP000001408};
RX   PubMed=12712204; DOI=10.1038/nature01597;
RA   Ren S.X., Fu G., Jiang X.G., Zeng R., Miao Y.G., Xu H., Zhang Y.X.,
RA   Xiong H., Lu G., Lu L.F., Jiang H.Q., Jia J., Tu Y.F., Jiang J.X., Gu W.Y.,
RA   Zhang Y.Q., Cai Z., Sheng H.H., Yin H.F., Zhang Y., Zhu G.F., Wan M.,
RA   Huang H.L., Qian Z., Wang S.Y., Ma W., Yao Z.J., Shen Y., Qiang B.Q.,
RA   Xia Q.C., Guo X.K., Danchin A., Saint Girons I., Somerville R.L., Wen Y.M.,
RA   Shi M.H., Chen Z., Xu J.G., Zhao G.P.;
RT   "Unique physiological and pathogenic features of Leptospira interrogans
RT   revealed by whole-genome sequencing.";
RL   Nature 422:888-893(2003).
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DR   EMBL; AE010300; AAN50119.1; -; Genomic_DNA.
DR   RefSeq; NP_713101.1; NC_004342.2.
DR   RefSeq; WP_000134480.1; NC_004342.2.
DR   AlphaFoldDB; Q8F256; -.
DR   STRING; 189518.LA_2921; -.
DR   PaxDb; 189518-LA_2921; -.
DR   EnsemblBacteria; AAN50119; AAN50119; LA_2921.
DR   KEGG; lil:LA_2921; -.
DR   PATRIC; fig|189518.3.peg.2901; -.
DR   HOGENOM; CLU_749635_0_0_12; -.
DR   InParanoid; Q8F256; -.
DR   OrthoDB; 9802426at2; -.
DR   Proteomes; UP000001408; Chromosome I.
DR   GO; GO:0016791; F:phosphatase activity; IBA:GO_Central.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR   CDD; cd00156; REC; 1.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   PANTHER; PTHR43156:SF12; STAGE II SPORULATION PROTEIN E; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF52172; CheY-like; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   4: Predicted;
KW   Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001408}.
FT   DOMAIN          9..123
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000259|PROSITE:PS50110"
FT   MOD_RES         58
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   369 AA;  41944 MW;  1D94D68EC02D4BBC CRC64;
     MTEFSLKPEI IILDDDRDVG ETLELILSKL GYQSVFFDSV EQGKQYFEKE LNPIVFLDIH
     MPGTSGLEIL PYFKNLESKT QVIMMTGERD INNVVTSLTH KASDFLLKPF SIQTVQIAIQ
     KAYDYYVILK EKDIREEVIM RDLRLASRVQ GKIFSIPDLS PYKVEADITP VSFVSGDFNV
     ILKKEKSVLV LLGDVEDHGV TSGLIALLMT TIAREEFKNS NNPSDILHRM NQELCLNIGT
     HSMTAACVIL FPNDKKLVYA RGGHPFPVHF HKAGFSFLKE KSGQLLGILE DLDFPSHEVL
     LEDKDVIFLF SDGIINNLNH PLISELDRIH KSEENPIKPM KKALDDFVRT SIPSKEYRDD
     SSYILLEIH
//