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Protein
Submitted name:

Adenylate/guanylate cyclase

Gene

cyaA

Organism
Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. phosphorus-oxygen lyase activity Source: InterPro
  2. signal transducer activity Source: InterPro

GO - Biological processi

  1. cyclic nucleotide biosynthetic process Source: InterPro
  2. intracellular signal transduction Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

BioCyciLINT189518:GJBB-2586-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Adenylate/guanylate cyclaseImported
Gene namesi
Name:cyaAImported
Ordered Locus Names:LA_3234Imported
OrganismiLeptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)Imported
Taxonomic identifieri189518 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesLeptospiraceaeLeptospira
ProteomesiUP000001408: Chromosome I

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi189518.LA3234.

Structurei

3D structure databases

ProteinModelPortaliQ8F1A2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000040325.
KOiK01768.
OMAiDERMEYT.
OrthoDBiEOG6VQPPK.

Family and domain databases

Gene3Di3.30.70.1230. 1 hit.
InterProiIPR001054. A/G_cyclase.
IPR003660. HAMP_linker_domain.
IPR029787. Nucleotide_cyclase.
[Graphical view]
PfamiPF00211. Guanylate_cyc. 1 hit.
PF00672. HAMP. 1 hit.
[Graphical view]
SMARTiSM00044. CYCc. 1 hit.
SM00304. HAMP. 1 hit.
[Graphical view]
SUPFAMiSSF55073. SSF55073. 1 hit.
PROSITEiPS50125. GUANYLATE_CYCLASE_2. 1 hit.
PS50885. HAMP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8F1A2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MYLSIFVGDK NNSAILVSLV KMDSILDSFK TSGITQFFLV GNDGALIAHS
60 70 80 90 100
DSKLILQPTD LKDEPIVKNL LESAISNGQT RYKGKDDQYY LGSFRRIGYA
110 120 130 140 150
GLGVISSTSE KKAFEEVYNI QKRNIYLMIV VVNVSILFVF FYARRLTRPI
160 170 180 190 200
LKLVDASKQI EQGNFHIDLK PESGDEIGRL TSSFVEMGKG LSDRDKMKDA
210 220 230 240 250
FGKFVNKDIA EMVLRGEVKL GGDKRECVIL FSDIRNFTSI SEKIEPELVV
260 270 280 290 300
EFLNQYFTAM VKCINENGGS VNKYIGDAIM AVWGELGHTN SDTERSILAA
310 320 330 340 350
LDMRKSLIQF NKGRGSDKKP KIFIGIGINT GEVIAGQIGS EDRLEYTVIG
360 370 380 390 400
DTVNLASRVE SLTKVFGADI LITGNSYEKV KGIFNVEKLK PIQVKGKKSL
410 420 430
QTIYAVLGHS KDKNCPKNLK ELRKQIGMEF KSGRSK
Length:436
Mass (Da):48,540
Last modified:March 1, 2003 - v1
Checksum:i836FD63CBD48F3A2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE010300 Genomic DNA. Translation: AAN50432.1.
RefSeqiNP_713414.1. NC_004342.2.

Genome annotation databases

EnsemblBacteriaiAAN50432; AAN50432; LA_3234.
GeneIDi1152576.
KEGGilil:LA_3234.
PATRICi22387298. VBILepInt91350_3210.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE010300 Genomic DNA. Translation: AAN50432.1.
RefSeqiNP_713414.1. NC_004342.2.

3D structure databases

ProteinModelPortaliQ8F1A2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi189518.LA3234.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN50432; AAN50432; LA_3234.
GeneIDi1152576.
KEGGilil:LA_3234.
PATRICi22387298. VBILepInt91350_3210.

Phylogenomic databases

HOGENOMiHOG000040325.
KOiK01768.
OMAiDERMEYT.
OrthoDBiEOG6VQPPK.

Enzyme and pathway databases

BioCyciLINT189518:GJBB-2586-MONOMER.

Family and domain databases

Gene3Di3.30.70.1230. 1 hit.
InterProiIPR001054. A/G_cyclase.
IPR003660. HAMP_linker_domain.
IPR029787. Nucleotide_cyclase.
[Graphical view]
PfamiPF00211. Guanylate_cyc. 1 hit.
PF00672. HAMP. 1 hit.
[Graphical view]
SMARTiSM00044. CYCc. 1 hit.
SM00304. HAMP. 1 hit.
[Graphical view]
SUPFAMiSSF55073. SSF55073. 1 hit.
PROSITEiPS50125. GUANYLATE_CYCLASE_2. 1 hit.
PS50885. HAMP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 56601Imported.

Entry informationi

Entry nameiQ8F1A2_LEPIN
AccessioniPrimary (citable) accession number: Q8F1A2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: February 4, 2015
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.