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Protein
Submitted name:

Adenylate/guanylate cyclase

Gene

cyaA

Organism
Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Adenylate/guanylate cyclaseImported
Gene namesi
Name:cyaAImported
Ordered Locus Names:LA_3234Imported
OrganismiLeptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)Imported
Taxonomic identifieri189518 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesLeptospiralesLeptospiraceaeLeptospira
Proteomesi
  • UP000001408 Componenti: Chromosome I

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei125 – 143HelicalSequence analysisAdd BLAST19

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi189518.LA_3234.

Structurei

3D structure databases

ProteinModelPortaliQ8F1A2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini144 – 196HAMPInterPro annotationAdd BLAST53
Domaini228 – 360Guanylate cyclaseInterPro annotationAdd BLAST133

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG4105F8J. Bacteria.
COG2114. LUCA.
HOGENOMiHOG000040325.
KOiK01768.
OMAiATIEMRR.

Family and domain databases

CDDicd06225. HAMP. 1 hit.
Gene3Di3.30.70.1230. 1 hit.
InterProiIPR001054. A/G_cyclase.
IPR003660. HAMP_dom.
IPR029787. Nucleotide_cyclase.
[Graphical view]
PfamiPF00211. Guanylate_cyc. 1 hit.
PF00672. HAMP. 1 hit.
[Graphical view]
SMARTiSM00044. CYCc. 1 hit.
SM00304. HAMP. 1 hit.
[Graphical view]
SUPFAMiSSF55073. SSF55073. 1 hit.
PROSITEiPS50125. GUANYLATE_CYCLASE_2. 1 hit.
PS50885. HAMP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8F1A2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYLSIFVGDK NNSAILVSLV KMDSILDSFK TSGITQFFLV GNDGALIAHS
60 70 80 90 100
DSKLILQPTD LKDEPIVKNL LESAISNGQT RYKGKDDQYY LGSFRRIGYA
110 120 130 140 150
GLGVISSTSE KKAFEEVYNI QKRNIYLMIV VVNVSILFVF FYARRLTRPI
160 170 180 190 200
LKLVDASKQI EQGNFHIDLK PESGDEIGRL TSSFVEMGKG LSDRDKMKDA
210 220 230 240 250
FGKFVNKDIA EMVLRGEVKL GGDKRECVIL FSDIRNFTSI SEKIEPELVV
260 270 280 290 300
EFLNQYFTAM VKCINENGGS VNKYIGDAIM AVWGELGHTN SDTERSILAA
310 320 330 340 350
LDMRKSLIQF NKGRGSDKKP KIFIGIGINT GEVIAGQIGS EDRLEYTVIG
360 370 380 390 400
DTVNLASRVE SLTKVFGADI LITGNSYEKV KGIFNVEKLK PIQVKGKKSL
410 420 430
QTIYAVLGHS KDKNCPKNLK ELRKQIGMEF KSGRSK
Length:436
Mass (Da):48,540
Last modified:March 1, 2003 - v1
Checksum:i836FD63CBD48F3A2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE010300 Genomic DNA. Translation: AAN50432.1.
RefSeqiNP_713414.1. NC_004342.2.
WP_011069744.1. NC_004342.2.

Genome annotation databases

EnsemblBacteriaiAAN50432; AAN50432; LA_3234.
GeneIDi1152576.
KEGGilil:LA_3234.
PATRICi22387298. VBILepInt91350_3210.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE010300 Genomic DNA. Translation: AAN50432.1.
RefSeqiNP_713414.1. NC_004342.2.
WP_011069744.1. NC_004342.2.

3D structure databases

ProteinModelPortaliQ8F1A2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi189518.LA_3234.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN50432; AAN50432; LA_3234.
GeneIDi1152576.
KEGGilil:LA_3234.
PATRICi22387298. VBILepInt91350_3210.

Phylogenomic databases

eggNOGiENOG4105F8J. Bacteria.
COG2114. LUCA.
HOGENOMiHOG000040325.
KOiK01768.
OMAiATIEMRR.

Family and domain databases

CDDicd06225. HAMP. 1 hit.
Gene3Di3.30.70.1230. 1 hit.
InterProiIPR001054. A/G_cyclase.
IPR003660. HAMP_dom.
IPR029787. Nucleotide_cyclase.
[Graphical view]
PfamiPF00211. Guanylate_cyc. 1 hit.
PF00672. HAMP. 1 hit.
[Graphical view]
SMARTiSM00044. CYCc. 1 hit.
SM00304. HAMP. 1 hit.
[Graphical view]
SUPFAMiSSF55073. SSF55073. 1 hit.
PROSITEiPS50125. GUANYLATE_CYCLASE_2. 1 hit.
PS50885. HAMP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ8F1A2_LEPIN
AccessioniPrimary (citable) accession number: Q8F1A2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: November 2, 2016
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.