ID   Q8F0P1_LEPIN            Unreviewed;       591 AA.
AC   Q8F0P1;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   27-MAR-2024, entry version 104.
DE   SubName: Full=Serine phosphatase RsbU {ECO:0000313|EMBL:AAN50649.1};
GN   Name=rsbU {ECO:0000313|EMBL:AAN50649.1};
GN   OrderedLocusNames=LA_3451 {ECO:0000313|EMBL:AAN50649.1};
OS   Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain
OS   56601).
OC   Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC   Leptospira.
OX   NCBI_TaxID=189518 {ECO:0000313|EMBL:AAN50649.1, ECO:0000313|Proteomes:UP000001408};
RN   [1] {ECO:0000313|EMBL:AAN50649.1, ECO:0000313|Proteomes:UP000001408}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=56601 {ECO:0000313|EMBL:AAN50649.1,
RC   ECO:0000313|Proteomes:UP000001408};
RX   PubMed=12712204; DOI=10.1038/nature01597;
RA   Ren S.X., Fu G., Jiang X.G., Zeng R., Miao Y.G., Xu H., Zhang Y.X.,
RA   Xiong H., Lu G., Lu L.F., Jiang H.Q., Jia J., Tu Y.F., Jiang J.X., Gu W.Y.,
RA   Zhang Y.Q., Cai Z., Sheng H.H., Yin H.F., Zhang Y., Zhu G.F., Wan M.,
RA   Huang H.L., Qian Z., Wang S.Y., Ma W., Yao Z.J., Shen Y., Qiang B.Q.,
RA   Xia Q.C., Guo X.K., Danchin A., Saint Girons I., Somerville R.L., Wen Y.M.,
RA   Shi M.H., Chen Z., Xu J.G., Zhao G.P.;
RT   "Unique physiological and pathogenic features of Leptospira interrogans
RT   revealed by whole-genome sequencing.";
RL   Nature 422:888-893(2003).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE010300; AAN50649.1; -; Genomic_DNA.
DR   RefSeq; NP_713631.1; NC_004342.2.
DR   RefSeq; WP_001070424.1; NC_004342.2.
DR   AlphaFoldDB; Q8F0P1; -.
DR   STRING; 189518.LA_3451; -.
DR   PaxDb; 189518-LA_3451; -.
DR   EnsemblBacteria; AAN50649; AAN50649; LA_3451.
DR   KEGG; lil:LA_3451; -.
DR   PATRIC; fig|189518.3.peg.3417; -.
DR   HOGENOM; CLU_456206_0_0_12; -.
DR   InParanoid; Q8F0P1; -.
DR   OrthoDB; 305353at2; -.
DR   Proteomes; UP000001408; Chromosome I.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   PANTHER; PTHR43156:SF12; STAGE II SPORULATION PROTEIN E; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001408};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        37..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        62..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        96..120
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        132..159
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        171..193
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          377..590
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|SMART:SM00331"
SQ   SEQUENCE   591 AA;  67291 MW;  74B4E04678BAC1D4 CRC64;
     MNPYILIPFS ALIINGSLFA YVSALKGKSE TVTLYQRFSF ILFIWHISLI LYWSFLPNDW
     PIIIFKVSSF SWIFIGCLFF EFAVRFSNSS FQFLIYLFRG LCLVSFLITI STDLVVQGII
     RAYWGDMIQA GPLYLPISIL VTGIPTLTGS LILIFNGLRS HNALLNKQFR LVAYGTIFSY
     LISFITTLLP RYWNTSLTFP PLSGSSALIQ SICIFIAIRK YGFMDLKLEH IALQLYAEIR
     EGVILLSSKG NLIFSNLSAK KMLGISDNVS TGSNFNLSDY LEGFPSDSFF ERKEFINLTV
     KIENHPSEII ENKYLEVSSS PISLSGKNDG KVYILRDITE KKDSLDKIRK LLYRLELDLD
     LARDIQQMIT SRNFPDSSDY KLYSYFQPYI KVGGDILNVI KEKDESLHIL FGDVSGHGIS
     AAMVAAMTSI AFGATTKRSD STDKNLLFIH ELLKDTITLH SFSSVYMRYI PYERKLEYTY
     GGHHCALLIR NKICIPVEGS GEILFTTPIP YLRRYELYLK KGDRILLYSD GLFQVKNREG
     NPLSQYQFLE AIRSLVVEDT NSMIRSILSY SSSYGDGEIS DDVTIFCLEV F
//