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Q8EZG6

- G6PI_LEPIN

UniProt

Q8EZG6 - G6PI_LEPIN

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Protein

Glucose-6-phosphate isomerase

Gene
pgi, LA_3888
Organism
Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei284 – 2841Proton donor By similarity
Active sitei305 – 3051 By similarity
Active sitei419 – 4191 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciLINT189518:GJBB-3084-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:LA_3888
OrganismiLeptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Taxonomic identifieri189518 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesLeptospiraceaeLeptospira
ProteomesiUP000001408: Chromosome I

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 445445Glucose-6-phosphate isomeraseUniRule annotationPRO_0000180665Add
BLAST

Proteomic databases

PaxDbiQ8EZG6.

Interactioni

Protein-protein interaction databases

STRINGi189518.LA3888.

Structurei

3D structure databases

ProteinModelPortaliQ8EZG6.
SMRiQ8EZG6. Positions 2-442.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000100403.
KOiK01810.
OMAiAIAFREF.
OrthoDBiEOG64R61J.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8EZG6-1 [UniParc]FASTAAdd to Basket

« Hide

MIRLETRFAS SFIQSSKLEP FLEKSESARL TLHSSQGQGK EYLGWLYLPK    50
ELKNSEIERM TQVAERLRNS SEVIVVIGIG GSYLGSRAVL EATLPFFKKP 100
SIGNPEIIFA GHHLESRYFS ELIEYLEDKN FSINVISKSG TTTEPAIAFR 150
LLWELLRKKY GSSASSRVVA TTDSSKGVLK KFADSEKLDT FTIPDNVGGR 200
YSVLTPVGLF PLAVAGISIS KFILGFQNIL NDIHSITDPT RNPATYYSAL 250
RNYFLSEGRY IEVLANFNPS LRYVSEWWKQ LFGESEGKEN KGIFPASMDF 300
TTDLHSLGQY IQEGKRILFE TVLSPSEVCS NLTLKPTQDN LDSLNFLSGN 350
TLGYVNEQAR LGTLLAHADG GVPCLELVFP DISPQSLGEL MYFFEYSCAI 400
SGYSLGVNPF DQPGVEAYKK NMFALLNKPG FEQEGETLRK RISRN 445
Length:445
Mass (Da):49,735
Last modified:March 1, 2003 - v1
Checksum:i5ACA2EAC6387A6A9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE010300 Genomic DNA. Translation: AAN51086.1.
RefSeqiNP_714068.1. NC_004342.2.

Genome annotation databases

EnsemblBacteriaiAAN51086; AAN51086; LA_3888.
GeneIDi1153230.
KEGGilil:LA_3888.
PATRICi22388601. VBILepInt91350_3855.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE010300 Genomic DNA. Translation: AAN51086.1 .
RefSeqi NP_714068.1. NC_004342.2.

3D structure databases

ProteinModelPortali Q8EZG6.
SMRi Q8EZG6. Positions 2-442.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 189518.LA3888.

Proteomic databases

PaxDbi Q8EZG6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAN51086 ; AAN51086 ; LA_3888 .
GeneIDi 1153230.
KEGGi lil:LA_3888.
PATRICi 22388601. VBILepInt91350_3855.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000100403.
KOi K01810.
OMAi AIAFREF.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
BioCyci LINT189518:GJBB-3084-MONOMER.

Family and domain databases

HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 56601.

Entry informationi

Entry nameiG6PI_LEPIN
AccessioniPrimary (citable) accession number: Q8EZG6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 23, 2003
Last sequence update: March 1, 2003
Last modified: June 11, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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