Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8EZG6

- G6PI_LEPIN

UniProt

Q8EZG6 - G6PI_LEPIN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei284 – 2841Proton donorUniRule annotation
Active sitei305 – 3051UniRule annotation
Active sitei419 – 4191UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciLINT189518:GJBB-3084-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:LA_3888
OrganismiLeptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Taxonomic identifieri189518 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesLeptospiraceaeLeptospira
ProteomesiUP000001408: Chromosome I

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 445445Glucose-6-phosphate isomerasePRO_0000180665Add
BLAST

Proteomic databases

PaxDbiQ8EZG6.

Interactioni

Protein-protein interaction databases

STRINGi189518.LA3888.

Structurei

3D structure databases

ProteinModelPortaliQ8EZG6.
SMRiQ8EZG6. Positions 2-442.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000100403.
InParanoidiQ8EZG6.
KOiK01810.
OMAiAIAFREF.
OrthoDBiEOG64R61J.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8EZG6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIRLETRFAS SFIQSSKLEP FLEKSESARL TLHSSQGQGK EYLGWLYLPK
60 70 80 90 100
ELKNSEIERM TQVAERLRNS SEVIVVIGIG GSYLGSRAVL EATLPFFKKP
110 120 130 140 150
SIGNPEIIFA GHHLESRYFS ELIEYLEDKN FSINVISKSG TTTEPAIAFR
160 170 180 190 200
LLWELLRKKY GSSASSRVVA TTDSSKGVLK KFADSEKLDT FTIPDNVGGR
210 220 230 240 250
YSVLTPVGLF PLAVAGISIS KFILGFQNIL NDIHSITDPT RNPATYYSAL
260 270 280 290 300
RNYFLSEGRY IEVLANFNPS LRYVSEWWKQ LFGESEGKEN KGIFPASMDF
310 320 330 340 350
TTDLHSLGQY IQEGKRILFE TVLSPSEVCS NLTLKPTQDN LDSLNFLSGN
360 370 380 390 400
TLGYVNEQAR LGTLLAHADG GVPCLELVFP DISPQSLGEL MYFFEYSCAI
410 420 430 440
SGYSLGVNPF DQPGVEAYKK NMFALLNKPG FEQEGETLRK RISRN
Length:445
Mass (Da):49,735
Last modified:March 1, 2003 - v1
Checksum:i5ACA2EAC6387A6A9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE010300 Genomic DNA. Translation: AAN51086.1.
RefSeqiNP_714068.1. NC_004342.2.

Genome annotation databases

EnsemblBacteriaiAAN51086; AAN51086; LA_3888.
GeneIDi1153230.
KEGGilil:LA_3888.
PATRICi22388601. VBILepInt91350_3855.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE010300 Genomic DNA. Translation: AAN51086.1 .
RefSeqi NP_714068.1. NC_004342.2.

3D structure databases

ProteinModelPortali Q8EZG6.
SMRi Q8EZG6. Positions 2-442.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 189518.LA3888.

Proteomic databases

PaxDbi Q8EZG6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAN51086 ; AAN51086 ; LA_3888 .
GeneIDi 1153230.
KEGGi lil:LA_3888.
PATRICi 22388601. VBILepInt91350_3855.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000100403.
InParanoidi Q8EZG6.
KOi K01810.
OMAi AIAFREF.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
BioCyci LINT189518:GJBB-3084-MONOMER.

Family and domain databases

HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 56601.

Entry informationi

Entry nameiG6PI_LEPIN
AccessioniPrimary (citable) accession number: Q8EZG6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 23, 2003
Last sequence update: March 1, 2003
Last modified: October 29, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3