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Q8EZ52

- Q8EZ52_LEPIN

UniProt

Q8EZ52 - Q8EZ52_LEPIN

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Protein
Submitted name:

Adenylate/guanylate cyclase

Gene

LA_4008

Organism
Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. phosphorus-oxygen lyase activity Source: InterPro

GO - Biological processi

  1. cyclic nucleotide biosynthetic process Source: InterPro
  2. intracellular signal transduction Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

BioCyciLINT189518:GJBB-3177-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Adenylate/guanylate cyclaseImported
Gene namesi
Ordered Locus Names:LA_4008Imported
OrganismiLeptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)Imported
Taxonomic identifieri189518 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesLeptospiraceaeLeptospira
ProteomesiUP000001408: Chromosome I

Interactioni

Protein-protein interaction databases

STRINGi189518.LA4008.

Structurei

3D structure databases

ProteinModelPortaliQ8EZ52.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000143764.
InParanoidiQ8EZ52.
KOiK01768.
OMAiETIAVFE.
OrthoDBiEOG63FVWZ.

Family and domain databases

Gene3Di1.25.40.10. 2 hits.
3.30.70.1230. 2 hits.
InterProiIPR001054. A/G_cyclase.
IPR029787. Nucleotide_cyclase.
IPR027417. P-loop_NTPase.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR019734. TPR_repeat.
[Graphical view]
PfamiPF00211. Guanylate_cyc. 1 hit.
PF13181. TPR_8. 1 hit.
[Graphical view]
SMARTiSM00044. CYCc. 1 hit.
SM00028. TPR. 3 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF55073. SSF55073. 2 hits.
PROSITEiPS50125. GUANYLATE_CYCLASE_2. 2 hits.
PS50005. TPR. 3 hits.
PS50293. TPR_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8EZ52-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNNTTESFKD TLELIRPYLP SGIVRRLANF GESKLQRSQS FEGAVLFFDV
60 70 80 90 100
VGFTPTTLAL AAKGTRGIDA LQIVLSNYYT GLLKHLNEWG GAVYQFAGDS
110 120 130 140 150
VLVSFEKREG ETAEEAALRV ANCALGISNS IAEYSSNELL GETVNLPARV
160 170 180 190 200
GLAYGVYQEF ILGEQDRFLR AVIAGAPVDQ SIAAEKQALG GDIILSSSLW
210 220 230 240 250
NLLPASKVGE NVNSDFFRLI DCEKCENSVP PPSRSTTEER FSDERFFKRC
260 270 280 290 300
RRFIVPELYQ RVTSVHKAFS GDYREVASVF VRIDAPLESH SDSKNFNDFF
310 320 330 340 350
IYVQSVAASC SGTFVLTDLS DKGGVFSVLF GAPAALENKE ALAARFAVRL
360 370 380 390 400
MEGASNYSAA KNLQIGISTG MAYCGDLGAP FRKDFTAIGE MMNIAARLAT
410 420 430 440 450
LSGYSGILID FQTKSKLGKN FSFHEVGDVE LKGVTGAKKV FQLTSEQKNI
460 470 480 490 500
PGLLIQYKDK MIGRKEEIDR LHKMLDSSIE KGGVVCRIIA DAGLGKSRLT
510 520 530 540 550
NTFIDQAYDR NVEILIGYCY PYEKFTPFYP WKELLSLFLG IFEDDSTEAR
560 570 580 590 600
VAKAEKALEN LNSFDIAWAK ALVALMGVSV EEDPLTREID RKQKNERLFE
610 620 630 640 650
IIISLLQERA NKKPLMLVFE DVHWIDELSS RLLEKLAFRL SEMKVMLLLV
660 670 680 690 700
SRPEGQFGED SVAPNEELIR LKEFKSEEAK DFLIHKFKLD TSHEEFLDQI
710 720 730 740 750
LNRSSGNPFF LESIVHNLIE EGTLIKLEDG TLSPSDKTRD IQIPNTLNDV
760 770 780 790 800
LLARVDRLQE REKIVLKTAS VIGRLINVDT LNHLLPVEFR SQIDNILQSL
810 820 830 840 850
EGLDLTPLEV TEPLTYIFKH IVIRDIVYNT LLHSTREDLH KKIASFIEKE
860 870 880 890 900
NENNLTEMAD ILAFHYQQCS DFEKASKYSL MAARKARSKY ANRDAIYHYG
910 920 930 940 950
KTLETLAQFE KTKSETYYEI KLELAHVHRQ FGEYSIAEVL FKECLENKST
960 970 980 990 1000
LNLIRSYTGL GQVYQEQDDI SRAMETLENA LRITGIRPPG SRPDTILKIV
1010 1020 1030 1040 1050
LQLTLVLRFS FFGPSYTSSN KAERLRLRCI ILATLAKMYI MKDVKKFGWS
1060 1070 1080 1090 1100
VFTQYNATQR FEDPVRSSLA ECALGQVFVG MNLFGPSKHF LLKGRELAEK
1110 1120 1130 1140 1150
TGDPYARAIS LLVQGGYYMM LNRPELGLPF LQDSISIYRQ VGEKWDLLSA
1160 1170 1180 1190 1200
LSSSGFLYYF QSDFRTAKQY FDDIGEIASD LGAQLQLRWT RIWSPYFGYL
1210 1220 1230 1240 1250
LGEVEPPELE KKLIVEVERA ASENDVMNEL STINKLLKLS ILEGWPEKAE
1260 1270 1280 1290 1300
LWARRSYAGF LKCEVKFPQL QIGNVYLAEA ALYAQMENGN KNLTKIINYG
1310 1320 1330 1340 1350
LKNGLKLGKS LPYLYGPSLV LKGKLLFHSG KRKKAEAIFK EAESFLSNTQ
1360 1370 1380 1390
NRWEYATALY EIGELLGDTE RISTSKKILH ELGAKADLKR LDKIQL
Length:1,396
Mass (Da):157,623
Last modified:March 1, 2003 - v1
Checksum:iE1A9FA323704B2E0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE010300 Genomic DNA. Translation: AAN51206.1.
RefSeqiNP_714188.1. NC_004342.2.

Genome annotation databases

EnsemblBacteriaiAAN51206; AAN51206; LA_4008.
GeneIDi1153350.
KEGGilil:LA_4008.
PATRICi22388847. VBILepInt91350_3977.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE010300 Genomic DNA. Translation: AAN51206.1 .
RefSeqi NP_714188.1. NC_004342.2.

3D structure databases

ProteinModelPortali Q8EZ52.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 189518.LA4008.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAN51206 ; AAN51206 ; LA_4008 .
GeneIDi 1153350.
KEGGi lil:LA_4008.
PATRICi 22388847. VBILepInt91350_3977.

Phylogenomic databases

HOGENOMi HOG000143764.
InParanoidi Q8EZ52.
KOi K01768.
OMAi ETIAVFE.
OrthoDBi EOG63FVWZ.

Enzyme and pathway databases

BioCyci LINT189518:GJBB-3177-MONOMER.

Family and domain databases

Gene3Di 1.25.40.10. 2 hits.
3.30.70.1230. 2 hits.
InterProi IPR001054. A/G_cyclase.
IPR029787. Nucleotide_cyclase.
IPR027417. P-loop_NTPase.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR019734. TPR_repeat.
[Graphical view ]
Pfami PF00211. Guanylate_cyc. 1 hit.
PF13181. TPR_8. 1 hit.
[Graphical view ]
SMARTi SM00044. CYCc. 1 hit.
SM00028. TPR. 3 hits.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
SSF55073. SSF55073. 2 hits.
PROSITEi PS50125. GUANYLATE_CYCLASE_2. 2 hits.
PS50005. TPR. 3 hits.
PS50293. TPR_REGION. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 56601Imported.

Entry informationi

Entry nameiQ8EZ52_LEPIN
AccessioniPrimary (citable) accession number: Q8EZ52
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: October 29, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3