Q8EZ52 (Q8EZ52_LEPIN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Adenylate/guanylate cyclase EMBL AAN51206.1

Gene names

Ordered Locus Names:

LA_4008

Organism

Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601) [Reference proteome] [HAMAP] EMBL AAN51206.1

Taxonomic identifier

189518 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Spirochaetes › Spirochaetia › Spirochaetales › Leptospiraceae › Leptospira › Leptospira interrogans › Leptospira interrogans serovar Lai

Protein attributes

Sequence length	1396 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cyclic nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro intracellular signal transduction Inferred from electronic annotation. Source: InterPro
Molecular_function	phosphorus-oxygen lyase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8EZ52 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: E1A9FA323704B2E0	FASTA	1,396	157,623
	10 20 30 40 50 60 MNNTTESFKD TLELIRPYLP SGIVRRLANF GESKLQRSQS FEGAVLFFDV VGFTPTTLAL 70 80 90 100 110 120 AAKGTRGIDA LQIVLSNYYT GLLKHLNEWG GAVYQFAGDS VLVSFEKREG ETAEEAALRV 130 140 150 160 170 180 ANCALGISNS IAEYSSNELL GETVNLPARV GLAYGVYQEF ILGEQDRFLR AVIAGAPVDQ 190 200 210 220 230 240 SIAAEKQALG GDIILSSSLW NLLPASKVGE NVNSDFFRLI DCEKCENSVP PPSRSTTEER 250 260 270 280 290 300 FSDERFFKRC RRFIVPELYQ RVTSVHKAFS GDYREVASVF VRIDAPLESH SDSKNFNDFF 310 320 330 340 350 360 IYVQSVAASC SGTFVLTDLS DKGGVFSVLF GAPAALENKE ALAARFAVRL MEGASNYSAA 370 380 390 400 410 420 KNLQIGISTG MAYCGDLGAP FRKDFTAIGE MMNIAARLAT LSGYSGILID FQTKSKLGKN 430 440 450 460 470 480 FSFHEVGDVE LKGVTGAKKV FQLTSEQKNI PGLLIQYKDK MIGRKEEIDR LHKMLDSSIE 490 500 510 520 530 540 KGGVVCRIIA DAGLGKSRLT NTFIDQAYDR NVEILIGYCY PYEKFTPFYP WKELLSLFLG 550 560 570 580 590 600 IFEDDSTEAR VAKAEKALEN LNSFDIAWAK ALVALMGVSV EEDPLTREID RKQKNERLFE 610 620 630 640 650 660 IIISLLQERA NKKPLMLVFE DVHWIDELSS RLLEKLAFRL SEMKVMLLLV SRPEGQFGED 670 680 690 700 710 720 SVAPNEELIR LKEFKSEEAK DFLIHKFKLD TSHEEFLDQI LNRSSGNPFF LESIVHNLIE 730 740 750 760 770 780 EGTLIKLEDG TLSPSDKTRD IQIPNTLNDV LLARVDRLQE REKIVLKTAS VIGRLINVDT 790 800 810 820 830 840 LNHLLPVEFR SQIDNILQSL EGLDLTPLEV TEPLTYIFKH IVIRDIVYNT LLHSTREDLH 850 860 870 880 890 900 KKIASFIEKE NENNLTEMAD ILAFHYQQCS DFEKASKYSL MAARKARSKY ANRDAIYHYG 910 920 930 940 950 960 KTLETLAQFE KTKSETYYEI KLELAHVHRQ FGEYSIAEVL FKECLENKST LNLIRSYTGL 970 980 990 1000 1010 1020 GQVYQEQDDI SRAMETLENA LRITGIRPPG SRPDTILKIV LQLTLVLRFS FFGPSYTSSN 1030 1040 1050 1060 1070 1080 KAERLRLRCI ILATLAKMYI MKDVKKFGWS VFTQYNATQR FEDPVRSSLA ECALGQVFVG 1090 1100 1110 1120 1130 1140 MNLFGPSKHF LLKGRELAEK TGDPYARAIS LLVQGGYYMM LNRPELGLPF LQDSISIYRQ 1150 1160 1170 1180 1190 1200 VGEKWDLLSA LSSSGFLYYF QSDFRTAKQY FDDIGEIASD LGAQLQLRWT RIWSPYFGYL 1210 1220 1230 1240 1250 1260 LGEVEPPELE KKLIVEVERA ASENDVMNEL STINKLLKLS ILEGWPEKAE LWARRSYAGF 1270 1280 1290 1300 1310 1320 LKCEVKFPQL QIGNVYLAEA ALYAQMENGN KNLTKIINYG LKNGLKLGKS LPYLYGPSLV 1330 1340 1350 1360 1370 1380 LKGKLLFHSG KRKKAEAIFK EAESFLSNTQ NRWEYATALY EIGELLGDTE RISTSKKILH 1390 ELGAKADLKR LDKIQL

References

[1]

"Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing." Ren S.-X., Fu G., Jiang X.-G., Zeng R., Miao Y.-G., Xu H., Zhang Y.-X., Xiong H., Lu G., Lu L.-F., Jiang H.-Q., Jia J., Tu Y.-F., Jiang J.-X., Gu W.-Y., Zhang Y.-Q., Cai Z., Sheng H.-H. , Yin H.-F., Zhang Y., Zhu G.-F., Wan M., Huang H.-L., Qian Z., Wang S.-Y., Ma W., Yao Z.-J., Shen Y., Qiang B.-Q., Xia Q.-C., Guo X.-K., Danchin A., Saint Girons I., Somerville R.L., Wen Y.-M., Shi M.-H., Chen Z., Xu J.-G., Zhao G.-P. Nature 422:888-893(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 56601.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE010300 Genomic DNA. Translation: AAN51206.1.
RefSeq	NP_714188.1. NC_004342.2.
3D structure databases
ProteinModelPortal	Q8EZ52.
ModBase	Search...
Protein-protein interaction databases
STRING	189518.LA4008.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAN51206; AAN51206; LA_4008.
GeneID	1153350.
KEGG	lil:LA_4008.
PATRIC	22388847. VBILepInt91350_3977.
Phylogenomic databases
HOGENOM	HOG000143764.
KO	K01768.
OMA	VAYEGIL.
ProtClustDB	CLSK814229.
Enzyme and pathway databases
BioCyc	LINT189518:GJBB-3177-MONOMER.
Family and domain databases
Gene3D	1.25.40.10. 2 hits. 3.30.70.1230. 2 hits.
InterPro	IPR001054. A/G_cyclase. IPR027417. P-loop_NTPase. IPR013026. TPR-contain_dom. IPR011990. TPR-like_helical. IPR019734. TPR_repeat. [Graphical view]
Pfam	PF00211. Guanylate_cyc. 1 hit. PF13181. TPR_8. 1 hit. [Graphical view]
SMART	SM00044. CYCc. 1 hit. SM00028. TPR. 3 hits. [Graphical view]
SUPFAM	SSF55073. A/G_cyclase. 2 hits. SSF52540. SSF52540. 1 hit.
PROSITE	PS50125. GUANYLATE_CYCLASE_2. 2 hits. PS50005. TPR. 3 hits. PS50293. TPR_REGION. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8EZ52_LEPIN

Accession

Primary (citable) accession number: Q8EZ52

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	May 29, 2013
This is version 67 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)