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Protein
Submitted name:

Adenylate/guanylate cyclase

Gene

LB_094

Organism
Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

BioCyciLINT189518:G1GL4-3525-MONOMER

Names & Taxonomyi

Protein namesi
Submitted name:
Adenylate/guanylate cyclaseImported
Gene namesi
Ordered Locus Names:LB_094Imported
OrganismiLeptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)Imported
Taxonomic identifieri189518 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesLeptospiralesLeptospiraceaeLeptospira
Proteomesi
  • UP000001408 Componenti: Chromosome II

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei42 – 60HelicalSequence analysisAdd BLAST19
Transmembranei612 – 635HelicalSequence analysisAdd BLAST24

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi189518.LB_094

Structurei

3D structure databases

ProteinModelPortaliQ8EXW3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini632 – 684HAMPInterPro annotationAdd BLAST53
Domaini717 – 854Guanylate cyclaseInterPro annotationAdd BLAST138

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili101 – 121Sequence analysisAdd BLAST21
Coiled coili192 – 247Sequence analysisAdd BLAST56
Coiled coili786 – 806Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG4105F8J Bacteria
COG2114 LUCA
HOGENOMiHOG000041023
InParanoidiQ8EXW3
KOiK01768
OMAiMRTANTA

Family and domain databases

CDDicd06225 HAMP, 1 hit
Gene3Di3.30.70.1230, 1 hit
InterProiView protein in InterPro
IPR001054 A/G_cyclase
IPR003660 HAMP_dom
IPR029787 Nucleotide_cyclase
PfamiView protein in Pfam
PF00211 Guanylate_cyc, 1 hit
SMARTiView protein in SMART
SM00044 CYCc, 1 hit
SM00304 HAMP, 1 hit
SUPFAMiSSF55073 SSF55073, 1 hit
PROSITEiView protein in PROSITE
PS50125 GUANYLATE_CYCLASE_2, 1 hit
PS50885 HAMP, 1 hit

Sequencei

Sequence statusi: Complete.

Q8EXW3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATDQIESKE SQTSSFLRKI RNQLKWIGHF RNLFYLGIRA KLAIFTGTLI
60 70 80 90 100
AFTVMILTAI DVHQQTEILT QSYEKEASIS RHYISGLVLE LENLSNSLIR
110 120 130 140 150
VESFREKVKR QSQALRKYRT KIVTQETKEL NLFGFKTKLF GVLGKERKSS
160 170 180 190 200
IKETYYSVYL SKADIDELEK NTKILLKDPN GLAISDETCS KLKNIAHQVV
210 220 230 240 250
VLEADLNEQK QKLEELRVSE KTSEKEKQNL EQEMDHLKKG IEKTRNQLDQ
260 270 280 290 300
SILELSLPKQ HKKIEELGLN MSQYRIQTFP VVFNQSRENL IPSFDTKIFK
310 320 330 340 350
PEASINSNIF LNDIDISLKD SISKIISLDF SQDTNKNSYT IGKMELQVLY
360 370 380 390 400
SPIFKNQNST QRANRLKKEL PDFAKRYLQQ DANIALKVRE LVIPLKKRVQ
410 420 430 440 450
ELKEKKPPIP PFRDKTFNDL YARYSKLIEE RQTVFETFRN EYSEDKKSLK
460 470 480 490 500
ETSQKLNVSK RARSVKTKVF FPIQNENDVL IDALGELRNA GLEDLIVLRF
510 520 530 540 550
SQNFGNYSDY LKYPKEQNLS KERWKSIREW IYSGRSETPT PQLKKLISYG
560 570 580 590 600
IVSHSRAEAE EILWSLDSKP LFVKSGDDVS SAILSANLSG ISRTIVDRTE
610 620 630 640 650
GLETIQKNKN SAVATALLIC VASLIFAILI SGFVVQKIKR IIFHAKAVGQ
660 670 680 690 700
GNLEVQFEQG GKDELGTLTI ALNSMVTGLK EREKIKNILG TMIDPVVVKE
710 720 730 740 750
AMVDLAALKR GSEKRITAFF SDVANFSNIS EKLTSIELAS LLNEYLSAMT
760 770 780 790 800
LILKKHEGVL DKYIGDAIVG IFNAPVEVDE HCIKAARAAV EMIETLERLR
810 820 830 840 850
QEWKAKKVYI VEAQEMQIRI GLNTGLAKVG FMGTDSISAY TMMGDMVNLA
860 870 880 890 900
ARLEAAGKDY GVSILVSESV QREIKEEFFT RLLDVVRVKG KNESVQLYEL
910 920 930 940 950
IGRTDNVSER LEASVLEFSK GFEAYLNREW SLAQELFESS QITRGVKDKA
960 970
AILLTERCEE YKRNPPEKNW DGVYTRTHK
Length:979
Mass (Da):111,796
Last modified:March 1, 2003 - v1
Checksum:i1D102831B5091128
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE010301 Genomic DNA Translation: AAN51653.1
RefSeqiNP_714638.1, NC_004343.2
WP_000179789.1, NC_004343.2

Genome annotation databases

EnsemblBacteriaiAAN51653; AAN51653; LB_094
GeneIDi1154020
KEGGilil:LB_094
PATRICifig|189518.3.peg.4422

Similar proteinsi

Entry informationi

Entry nameiQ8EXW3_LEPIN
AccessioniPrimary (citable) accession number: Q8EXW3
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: March 28, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health