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Protein
Submitted name:

Adenylate/guanylate cyclase

Gene

LB_118

Organism
Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. phosphorus-oxygen lyase activity Source: InterPro

GO - Biological processi

  1. cyclic nucleotide biosynthetic process Source: InterPro
  2. intracellular signal transduction Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

BioCyciLINT189518:GJBB-3553-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Adenylate/guanylate cyclaseImported
Gene namesi
Ordered Locus Names:LB_118Imported
OrganismiLeptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)Imported
Taxonomic identifieri189518 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesLeptospiraceaeLeptospira
ProteomesiUP000001408: Chromosome II

Interactioni

Protein-protein interaction databases

STRINGi189518.LB118.

Structurei

3D structure databases

ProteinModelPortaliQ8EXU0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000118029.
InParanoidiQ8EXU0.
KOiK01768.
OMAiDISEHYI.
OrthoDBiEOG6G7QZK.

Family and domain databases

Gene3Di3.30.70.1230. 1 hit.
InterProiIPR011623. 7TMR_DISM_rcpt_extracell_dom1.
IPR001054. A/G_cyclase.
IPR029787. Nucleotide_cyclase.
IPR013026. TPR-contain_dom.
IPR019734. TPR_repeat.
[Graphical view]
PfamiPF07695. 7TMR-DISM_7TM. 1 hit.
PF00211. Guanylate_cyc. 1 hit.
[Graphical view]
SMARTiSM00044. CYCc. 1 hit.
[Graphical view]
SUPFAMiSSF55073. SSF55073. 1 hit.
PROSITEiPS50125. GUANYLATE_CYCLASE_2. 1 hit.
PS50005. TPR. 1 hit.
PS50293. TPR_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8EXU0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTILFFFCV TIPFWILAES QDSWKPIDLR KGNWIAVEGF QREYLNGIDS
60 70 80 90 100
TFSKSKKISH FPVVLNEIFE TSVETGLKEY TLQTRFHIQE DFQKTKVYKP
110 120 130 140 150
IFLYLESIGE NWEIFLNDHS LAQEIHLDIS HKEMILRRTI RSFRLPVDSS
160 170 180 190 200
LLRSGENLLT FRLIGDAPAS FLSKNVDLGF YIDGDYSLTT EQKLSGEIST
210 220 230 240 250
LINLCLNTIY VFFGFYHLLI YVKRREDLYN LYFGIFSVFM ALYSLSRSNI
260 270 280 290 300
AFEVIYDTTW ITRIEYSSVS LLAPLFLLFM QDYFYGRAKF SKVLFAILIL
310 320 330 340 350
NVVIALTTLL EPFRYTMTSL RLWQISILPT LVYLLYFMSK AVYLRKKDAI
360 370 380 390 400
LLATSMFTVV FIAVYDVIDS IFFQSGIRFT QFAYFLFVVA LTTILANRFI
410 420 430 440 450
SLYRQSEDLN IELSQQKLEL ARQKNAFFRF VPVQFLNVLG KNSAVEVNLG
460 470 480 490 500
DSVLKEMSVL FTDIRSFTTI SEQMTPEENF RFINDYLASM EPVVQRHEGF
510 520 530 540 550
VDKFMGDGIL ALFSGDGEIT RSHQTSADKA ILAAIEMKKK VQTINAQAKD
560 570 580 590 600
SHFRGLKIGI GINTGNLMLG TVGSRSRLDT TVIGDTVNVA SRLESLTNLY
610 620 630 640 650
RADILITKST LSAMTIADNL AIREIDSVVV KGKTDPIIIY EIYEADEPLI
660 670 680 690 700
RKLKDATLSL ITRGIILYKV ADFQEALINF EQALKIFPED IVPILYRKRC
710 720
QEYITSPPTG NWVGVQHLLE K
Length:721
Mass (Da):82,808
Last modified:March 1, 2003 - v1
Checksum:iC195E380AA38EEE2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE010301 Genomic DNA. Translation: AAN51677.1.
RefSeqiNP_714662.1. NC_004343.2.

Genome annotation databases

EnsemblBacteriaiAAN51677; AAN51677; LB_118.
GeneIDi1154044.
KEGGilil:LB_118.
PATRICi22389795. VBILepInt91350_4448.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE010301 Genomic DNA. Translation: AAN51677.1.
RefSeqiNP_714662.1. NC_004343.2.

3D structure databases

ProteinModelPortaliQ8EXU0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi189518.LB118.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN51677; AAN51677; LB_118.
GeneIDi1154044.
KEGGilil:LB_118.
PATRICi22389795. VBILepInt91350_4448.

Phylogenomic databases

HOGENOMiHOG000118029.
InParanoidiQ8EXU0.
KOiK01768.
OMAiDISEHYI.
OrthoDBiEOG6G7QZK.

Enzyme and pathway databases

BioCyciLINT189518:GJBB-3553-MONOMER.

Family and domain databases

Gene3Di3.30.70.1230. 1 hit.
InterProiIPR011623. 7TMR_DISM_rcpt_extracell_dom1.
IPR001054. A/G_cyclase.
IPR029787. Nucleotide_cyclase.
IPR013026. TPR-contain_dom.
IPR019734. TPR_repeat.
[Graphical view]
PfamiPF07695. 7TMR-DISM_7TM. 1 hit.
PF00211. Guanylate_cyc. 1 hit.
[Graphical view]
SMARTiSM00044. CYCc. 1 hit.
[Graphical view]
SUPFAMiSSF55073. SSF55073. 1 hit.
PROSITEiPS50125. GUANYLATE_CYCLASE_2. 1 hit.
PS50005. TPR. 1 hit.
PS50293. TPR_REGION. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 56601Imported.

Entry informationi

Entry nameiQ8EXU0_LEPIN
AccessioniPrimary (citable) accession number: Q8EXU0
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: January 7, 2015
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.