Unreviewed, UniProtKB/TrEMBL Q8EXU0 (Q8EXU0_LEPIN)

Names and origin

Protein names

Submitted name:
    Adenylate cyclase EMBL AAN51677.1
    EC=4.6.1.1

Gene names

Name:	cyaA18 EMBL AAN51677.1
Ordered Locus Names:	LB118
ORF Names:	LB_118 EMBL AAN51677.1

Organism

Leptospira interrogans [Complete proteome] [HAMAP]

Taxonomic identifier

173 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Leptospiraceae › Leptospira

Protein attributes

Sequence length	721 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Predicted.

Ontologies

Keywords
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cyclic nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro intracellular signaling cascade Inferred from electronic annotation. Source: InterPro
Molecular function	adenylate cyclase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8EXU0-1 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: C195E380AA38EEE2	FASTA	721	82,808
	10 20 30 40 50 60 MKTILFFFCV TIPFWILAES QDSWKPIDLR KGNWIAVEGF QREYLNGIDS TFSKSKKISH 70 80 90 100 110 120 FPVVLNEIFE TSVETGLKEY TLQTRFHIQE DFQKTKVYKP IFLYLESIGE NWEIFLNDHS 130 140 150 160 170 180 LAQEIHLDIS HKEMILRRTI RSFRLPVDSS LLRSGENLLT FRLIGDAPAS FLSKNVDLGF 190 200 210 220 230 240 YIDGDYSLTT EQKLSGEIST LINLCLNTIY VFFGFYHLLI YVKRREDLYN LYFGIFSVFM 250 260 270 280 290 300 ALYSLSRSNI AFEVIYDTTW ITRIEYSSVS LLAPLFLLFM QDYFYGRAKF SKVLFAILIL 310 320 330 340 350 360 NVVIALTTLL EPFRYTMTSL RLWQISILPT LVYLLYFMSK AVYLRKKDAI LLATSMFTVV 370 380 390 400 410 420 FIAVYDVIDS IFFQSGIRFT QFAYFLFVVA LTTILANRFI SLYRQSEDLN IELSQQKLEL 430 440 450 460 470 480 ARQKNAFFRF VPVQFLNVLG KNSAVEVNLG DSVLKEMSVL FTDIRSFTTI SEQMTPEENF 490 500 510 520 530 540 RFINDYLASM EPVVQRHEGF VDKFMGDGIL ALFSGDGEIT RSHQTSADKA ILAAIEMKKK 550 560 570 580 590 600 VQTINAQAKD SHFRGLKIGI GINTGNLMLG TVGSRSRLDT TVIGDTVNVA SRLESLTNLY 610 620 630 640 650 660 RADILITKST LSAMTIADNL AIREIDSVVV KGKTDPIIIY EIYEADEPLI RKLKDATLSL 670 680 690 700 710 720 ITRGIILYKV ADFQEALINF EQALKIFPED IVPILYRKRC QEYITSPPTG NWVGVQHLLE K

References

[1]

"Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing." Ren S.-X., Fu G., Jiang X.-G., Zeng R., Miao Y.-G., Xu H., Zhang Y.-X., Xiong H., Lu G., Lu L.-F., Jiang H.-Q., Jia J., Tu Y.-F., Jiang J.-X., Gu W.-Y., Zhang Y.-Q., Cai Z., Sheng H.-H. , Yin H.-F., Zhang Y., Zhu G.-F., Wan M., Huang H.-L., Qian Z., Wang S.-Y., Ma W., Yao Z.-J., Shen Y., Qiang B.-Q., Xia Q.-C., Guo X.-K., Danchin A., Saint Girons I., Somerville R.L., Wen Y.-M., Shi M.-H., Chen Z., Xu J.-G., Zhao G.-P. Nature 422:888-893(2003) [PubMed: 12712204] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 56601 / Serogroup Icterohaemorrhagiae / Serovar lai.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE010301 Genomic DNA. Translation: AAN51677.1.
RefSeq	NP_714662.1.
3D structure databases
HSSP	HSSP built from PDB template 1AB8 based on UniProtKB P26769.
ModBase	Search...
Genome annotation databases
GeneID	1154044.
GenomeReviews	Gene locus LB118 in contig AE010301_GR.
KEGG	lil:LB118.
NMPDR	fig|189518.1.peg.4478.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8EXU0.
OMA	Q8EXU0. TWITRIE.
Enzyme and pathway databases
BioCyc	LINT189518:LB118-MON.
Family and domain databases
InterPro	IPR011623. 7TMR_DISM_TM. IPR001054. A/G_cyclase. IPR013105. TPR_2. IPR013026. TPR_region. IPR019734. TPR_repeat. [Graphical view]
Gene3D	G3DSA:3.30.70.1230. A/G_cyclase. 1 hit.
Pfam	PF07695. 7TMR-DISM_7TM. 1 hit. PF00211. Guanylate_cyc. 1 hit. PF07719. TPR_2. 1 hit. [Graphical view]
SMART	SM00044. CYCc. 1 hit. [Graphical view]
PROSITE	PS50125. GUANYLATE_CYCLASE_2. 1 hit. PS50005. TPR. 1 hit. PS50293. TPR_REGION. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8EXU0_LEPIN

Accession

Primary (citable) accession number: Q8EXU0

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	May 5, 2009
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)