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Q8EWR4 (FENR_MYCPE) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferredoxin--NADP reductase
Short name=FNR
Short name=Fd-NADP+ reductase
EC=1.18.1.2
Gene names
Ordered Locus Names:MYPE1390
OrganismMycoplasma penetrans (strain HF-2) [Complete proteome] [HAMAP]
Taxonomic identifier272633 [NCBI]
Taxonomic lineageBacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma

Protein attributes

Sequence length322 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH. HAMAP MF_01685

Cofactor

Binds 1 FAD per subunit By similarity. HAMAP MF_01685

Subunit structure

Homodimer By similarity. HAMAP MF_01685

Sequence similarities

Belongs to the ferredoxin--NADP reductase type 2 family.

Ontologies

Keywords
   LigandFAD
Flavoprotein
NADP
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionferredoxin-NADP+ reductase activity

Inferred from electronic annotation. Source: EC

flavin adenine dinucleotide binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 322322Ferredoxin--NADP reductase HAMAP MF_01685
PRO_0000364883

Sites

Binding site371FAD By similarity
Binding site451FAD By similarity
Binding site501FAD By similarity
Binding site911FAD; via amide nitrogen and carbonyl oxygen By similarity
Binding site1281FAD; via amide nitrogen By similarity
Binding site2901FAD By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8EWR4 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 383EACB315548418

FASTA32237,129
        10         20         30         40         50         60 
MNEDLRIYDV AIVGGGAGGI FASTISNYFN LNSILIEKKS YLGGQPMELY PNKFIYDFPC 

        70         80         90        100        110        120 
FFEIKSSDVI KKLIQQNKEQ KNSNIQLDTD ILNITWQTIN EQELFLFETN KNSFYAKKII 

       130        140        150        160        170        180 
LASGNGSFNP RKLEINNEPI DSPFIHYSLN LETEIYKNKK ILVLGGGDSA VEWANYFVEE 

       190        200        210        220        230        240 
KITNNVAIIH RRNEYRSSSF MIDCLSKNNI LQKLNYEIID FNESNKTLTI KHKETEKEQT 

       250        260        270        280        290        300 
LPFDYVLVQY GQISSPINIE LLNQINKEKG KYVIDLNQKT NIKNIYAIGD ATHFYCKPNT 

       310        320 
IITACAEAVR ALWHISKNKK DW

« Hide

References

[1]"The complete genomic sequence of Mycoplasma penetrans, an intracellular bacterial pathogen in humans."
Sasaki Y., Ishikawa J., Yamashita A., Oshima K., Kenri T., Furuya K., Yoshino C., Horino A., Shiba T., Sasaki T., Hattori M.
Nucleic Acids Res. 30:5293-5300(2002) [PubMed: 12466555] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HF-2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000026 Genomic DNA. Translation: BAC43930.1.
RefSeqNP_757526.1. NC_004432.1.

3D structure databases

ProteinModelPortalQ8EWR4.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1040779.
GenomeReviewsGene locus MYPE1390 in contig BA000026_GR.
KEGGmpe:MYPE1390.
NMPDRfig|272633.1.peg.140.
PATRIC20019375. VBIMycPen56664_0143.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG129636.
OMAYPNKQKL.
PhylomeDBQ8EWR4.
ProtClustDBCLSK335432.

Enzyme and pathway databases

BioCycMPEN272633:MYPE1390-MONOMER.

Family and domain databases

HAMAPMF_01685. FENR2.
[Tree]
InterProIPR013027. FAD_pyr_nucl-diS_OxRdtase.
IPR022890. Fd--NADP_Rdtase_type_2.
IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD.
IPR001327. Pyr_OxRdtase_NAD-bd_dom.
IPR000103. Pyridine_nuc-diS_OxRdtase_2.
[Graphical view]
KOK00384.
PANTHERPTHR22912:SF53. PTHR22912:SF53. 1 hit.
PfamPF00070. Pyr_redox. 1 hit.
PF07992. Pyr_redox_2. 1 hit.
[Graphical view]
PRINTSPR00368. FADPNR.
PR00469. PNDRDTASEII.
ProtoNetSearch...

Entry information

Entry nameFENR_MYCPE
AccessionPrimary (citable) accession number: Q8EWR4
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: March 1, 2003
Last modified: January 25, 2012
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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