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Q8EVU1

- G6PI_MYCPE

UniProt

Q8EVU1 - G6PI_MYCPE

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Mycoplasma penetrans (strain HF-2)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 67 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei284 – 2841Proton donorUniRule annotation
    Active sitei305 – 3051UniRule annotation
    Active sitei420 – 4201UniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    BioCyciMPEN272633:GJBP-493-MONOMER.
    UniPathwayiUPA00109; UER00181.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
    Short name:
    GPIUniRule annotation
    Alternative name(s):
    Phosphoglucose isomeraseUniRule annotation
    Short name:
    PGIUniRule annotation
    Phosphohexose isomeraseUniRule annotation
    Short name:
    PHIUniRule annotation
    Gene namesi
    Name:pgiUniRule annotation
    Ordered Locus Names:MYPE4690
    OrganismiMycoplasma penetrans (strain HF-2)
    Taxonomic identifieri272633 [NCBI]
    Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
    ProteomesiUP000002522: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 429429Glucose-6-phosphate isomerasePRO_0000180685Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi272633.MYPE4690.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8EVU1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0166.
    HOGENOMiHOG000100403.
    KOiK01810.
    OMAiQVIFIGN.
    OrthoDBiEOG64R61J.

    Family and domain databases

    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8EVU1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIKLNFTNFL EGNKSTEKIF KSYASKIETL NNSIEEKKCK GASMLGWMDY    50
    PSKYNKNEIK ELINVSQEWY NNKKIKNVVV LGIGGSYIGV RAGIDWVLPE 100
    FNREKEIYYV SSMSSSYVYS LIEKLKKEDF YLIVISKSGT TLEIGVAFRL 150
    FYSLLFEKFG SEGAKERTVA ITDKEKGTLR KIADTQDIQT FSIPDDVGGR 200
    FSAITPVGLF AMGVMGLDVN KVLKGCAKAI EDTKEPDIEK NTAYQYAALR 250
    HYMYSKKEKY NEVFCVYEDA LRFFTEHLKQ LFAESEGKEG KGLLPVNCLF 300
    TTDLHSVGQF LQEGNQIFFE TCISIKNPLN DVVINEFLKD EDGLGFLNGK 350
    KLDYINKVAA SSTIDAHHID GKIDIIQINL DNRNEESFGY LYSWFSKVVA 400
    MSGLLLKVNP FDQPGVEAYK SRMFTKLKK 429
    Length:429
    Mass (Da):48,750
    Last modified:March 1, 2003 - v1
    Checksum:i2089719F7A89B1BE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000026 Genomic DNA. Translation: BAC44258.1.
    RefSeqiNP_757854.1. NC_004432.1.
    WP_011077292.1. NC_004432.1.

    Genome annotation databases

    EnsemblBacteriaiBAC44258; BAC44258; BAC44258.
    GeneIDi1041253.
    KEGGimpe:MYPE4690.
    PATRICi20020085. VBIMycPen56664_0480.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000026 Genomic DNA. Translation: BAC44258.1 .
    RefSeqi NP_757854.1. NC_004432.1.
    WP_011077292.1. NC_004432.1.

    3D structure databases

    ProteinModelPortali Q8EVU1.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272633.MYPE4690.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAC44258 ; BAC44258 ; BAC44258 .
    GeneIDi 1041253.
    KEGGi mpe:MYPE4690.
    PATRICi 20020085. VBIMycPen56664_0480.

    Phylogenomic databases

    eggNOGi COG0166.
    HOGENOMi HOG000100403.
    KOi K01810.
    OMAi QVIFIGN.
    OrthoDBi EOG64R61J.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    BioCyci MPEN272633:GJBP-493-MONOMER.

    Family and domain databases

    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The complete genomic sequence of Mycoplasma penetrans, an intracellular bacterial pathogen in humans."
      Sasaki Y., Ishikawa J., Yamashita A., Oshima K., Kenri T., Furuya K., Yoshino C., Horino A., Shiba T., Sasaki T., Hattori M.
      Nucleic Acids Res. 30:5293-5300(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HF-2.

    Entry informationi

    Entry nameiG6PI_MYCPE
    AccessioniPrimary (citable) accession number: Q8EVU1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 23, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 67 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3