ID   Q8EVK1_MALP2            Unreviewed;       265 AA.
AC   Q8EVK1;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   27-MAR-2024, entry version 96.
DE   RecName: Full=protein-serine/threonine phosphatase {ECO:0000256|ARBA:ARBA00013081};
DE            EC=3.1.3.16 {ECO:0000256|ARBA:ARBA00013081};
GN   OrderedLocusNames=MYPE5620 {ECO:0000313|EMBL:BAC44352.1};
OS   Malacoplasma penetrans (strain HF-2) (Mycoplasma penetrans).
OC   Bacteria; Mycoplasmatota; Mycoplasmoidales; Mycoplasmoidaceae;
OC   Malacoplasma.
OX   NCBI_TaxID=272633 {ECO:0000313|EMBL:BAC44352.1, ECO:0000313|Proteomes:UP000002522};
RN   [1] {ECO:0000313|EMBL:BAC44352.1, ECO:0000313|Proteomes:UP000002522}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HF-2 {ECO:0000313|EMBL:BAC44352.1,
RC   ECO:0000313|Proteomes:UP000002522};
RX   PubMed=12466555; DOI=10.1093/nar/gkf667;
RA   Sasaki Y., Ishikawa J., Yamashita A., Oshima K., Kenri T., Furuya K.,
RA   Yoshino C., Horino A., Shiba T., Sasaki T., Hattori M.;
RT   "The complete genomic sequence of Mycoplasma penetrans, an intracellular
RT   bacterial pathogen in humans.";
RL   Nucleic Acids Res. 30:5293-5300(2002).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] +
CC         phosphate; Xref=Rhea:RHEA:20629, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC         COMP:11604, ChEBI:CHEBI:15377, ChEBI:CHEBI:29999, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:83421; EC=3.1.3.16;
CC         Evidence={ECO:0000256|ARBA:ARBA00001512};
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] +
CC         phosphate; Xref=Rhea:RHEA:47004, Rhea:RHEA-COMP:11060, Rhea:RHEA-
CC         COMP:11605, ChEBI:CHEBI:15377, ChEBI:CHEBI:30013, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:61977; EC=3.1.3.16;
CC         Evidence={ECO:0000256|ARBA:ARBA00001482};
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DR   EMBL; BA000026; BAC44352.1; -; Genomic_DNA.
DR   RefSeq; WP_011077385.1; NC_004432.1.
DR   AlphaFoldDB; Q8EVK1; -.
DR   STRING; 272633.gene:10731679; -.
DR   KEGG; mpe:MYPE5620; -.
DR   eggNOG; COG0631; Bacteria.
DR   HOGENOM; CLU_034545_4_1_14; -.
DR   InParanoid; Q8EVK1; -.
DR   Proteomes; UP000002522; Chromosome.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
DR   CDD; cd00143; PP2Cc; 1.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR015655; PP2C.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   PANTHER; PTHR47992:SF267; ALPHABET, ISOFORM E; 1.
DR   PANTHER; PTHR47992; PROTEIN PHOSPHATASE; 1.
DR   Pfam; PF13672; PP2C_2; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SMART; SM00332; PP2Cc; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   PROSITE; PS51746; PPM_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002522}.
FT   DOMAIN          22..262
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS51746"
SQ   SEQUENCE   265 AA;  30727 MW;  2C16A448CD4000D2 CRC64;
     MQKFNLEKFF NNNNNFIKLR RVLYSKSDTG TRQKNEDYAY CGTNKLLDNL LIVCDGIGSC
     RGSEKAAEIV AKTFVNSFLK QEYLLTNVNE WFEKNIERAK FAMIDHVLRF KDHNQMCTTL
     VLALSVEDTF HVFWIGDSRA YLIDKKSFEQ LSDDHNLLNY LIKTGTPQEE IEAKGKKIYS
     LMNYISINTK DKQEYDYVSF KIKKNSFVFL ASDGFYNFFS DLGSLYDILS HDGNAENLSN
     DLVNYALNNQ SNDNISFSYI GFLKD
//