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Q8EUV2

- PGK_MYCPE

UniProt

Q8EUV2 - PGK_MYCPE

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Protein

Phosphoglycerate kinase

Gene
pgk, MYPE8160
Organism
Mycoplasma penetrans (strain HF-2)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei41 – 411Substrate By similarity
Binding sitei127 – 1271Substrate By similarity
Binding sitei169 – 1691Substrate By similarity
Binding sitei220 – 2201ATP By similarity
Binding sitei307 – 3071ATP; via carbonyl oxygen By similarity
Binding sitei338 – 3381ATP By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi368 – 3714ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMPEN272633:GJBP-847-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:pgk
Ordered Locus Names:MYPE8160
OrganismiMycoplasma penetrans (strain HF-2)
Taxonomic identifieri272633 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000002522: Chromosome

Subcellular locationi

Cytoplasm Reviewed prediction UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 471471Phosphoglycerate kinaseUniRule annotationPRO_0000145970Add
BLAST

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi272633.MYPE8160.

Structurei

3D structure databases

ProteinModelPortaliQ8EUV2.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni24 – 263Substrate binding By similarity
Regioni64 – 674Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227107.
KOiK00927.
OMAiFPVDYVT.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8EUV2-1 [UniParc]FASTAAdd to Basket

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MEYNKKIVTD LTDLKGKKVI LRCDFNVPIN KTSGEITDYT RIDAALQTIN    50
YLLDKGVKLI VLSHLSRVKT LEDISSGKKS LKVVHKALKN RLLGKTVLFE 100
ENNRNKDLPK IIDGMEEGSL LLLENTRYAD VNEKGEVVKL ESKNDPSLGK 150
FWASLADIFV NDAFGTSHRA HASNVGIAKN IKESAIGFLV NKELAKLSKA 200
VVNPRKPVVA IFGGAKVSDK VPSIKNIGKF ADKILIGGGM AFIFLKAKGF 250
EIGKSLYEDD QLELTKELLS EFGNKIVLPV DAVVADSIKA AKGKRYDMEQ 300
FPADLAGFDV GKKTIKLFKK ELKLAETVIW NGPLGVFEND AFNKGTLKVC 350
KYIAKITAKK GCYSVIGGGD SAAAAAKCGV THSFSHISTG GGASLEFFSG 400
VELPGVACIK NKGEEGKVEA VKEKTTTTTE SASKEKSSTA KTASKPATSK 450
TTAAKKPAEK KPAAKKPAAK K 471
Length:471
Mass (Da):50,727
Last modified:March 1, 2003 - v1
Checksum:i10E631A553C41B7E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000026 Genomic DNA. Translation: BAC44609.1.
RefSeqiNP_758205.1. NC_004432.1.
WP_011077638.1. NC_004432.1.

Genome annotation databases

EnsemblBacteriaiBAC44609; BAC44609; BAC44609.
GeneIDi1041556.
KEGGimpe:MYPE8160.
PATRICi20020812. VBIMycPen56664_0840.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000026 Genomic DNA. Translation: BAC44609.1 .
RefSeqi NP_758205.1. NC_004432.1.
WP_011077638.1. NC_004432.1.

3D structure databases

ProteinModelPortali Q8EUV2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272633.MYPE8160.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAC44609 ; BAC44609 ; BAC44609 .
GeneIDi 1041556.
KEGGi mpe:MYPE8160.
PATRICi 20020812. VBIMycPen56664_0840.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227107.
KOi K00927.
OMAi FPVDYVT.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci MPEN272633:GJBP-847-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The complete genomic sequence of Mycoplasma penetrans, an intracellular bacterial pathogen in humans."
    Sasaki Y., Ishikawa J., Yamashita A., Oshima K., Kenri T., Furuya K., Yoshino C., Horino A., Shiba T., Sasaki T., Hattori M.
    Nucleic Acids Res. 30:5293-5300(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HF-2.

Entry informationi

Entry nameiPGK_MYCPE
AccessioniPrimary (citable) accession number: Q8EUV2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: March 1, 2003
Last modified: September 3, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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