Q8EUQ9 (GCP_MYCPE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	MYPE8610

Organism

Mycoplasma penetrans (strain HF-2) [Complete proteome] [HAMAP]

Taxonomic identifier

272633 [NCBI]

Taxonomic lineage

Bacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma

Protein attributes

Sequence length	306 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.
Sequence caution	The sequence BAC44653.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 306	306	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303444

Sequences

	Sequence		Length	Mass (Da)
	Q8EUQ9 [UniParc]. Last modified September 11, 2007. Version 2. Checksum: 72409CE98C74F99B	FASTA	306	34,040
	10 20 30 40 50 60 MYILSIETSC DDTSVAILED NKVLSCIIKN DSKQLNPFGG IVPEIVARYH EENIIKALDL 70 80 90 100 110 120 ALQESNISLN QIDKVAYTNQ PGLPGSLFVG EIFAKTMAYA LDVECVPINH IHGHILSPFI 130 140 150 160 170 180 NSVPKYPFMS LIASGKTTSI FLVKSANEII ELTKTRDDAI GEIFDKVGKA LGYDYPAGPK 190 200 210 220 230 240 LDKYFDISKA TITPSFPPVK NDFSFSGIKN KFLSIINSSK MKNEEIDTIT IGSSFLKYSI 250 260 270 280 290 300 DLIIKKLKYY KDEYSVDCVC IGGGVANNNY FKQEIKKLFS DSFVPESKYS TDNAAMIGFA YYEKNK

References

[1]

"The complete genomic sequence of Mycoplasma penetrans, an intracellular bacterial pathogen in humans." Sasaki Y., Ishikawa J., Yamashita A., Oshima K., Kenri T., Furuya K., Yoshino C., Horino A., Shiba T., Sasaki T., Hattori M. Nucleic Acids Res. 30:5293-5300(2002) [PubMed: 12466555] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HF-2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000026 Genomic DNA. Translation: BAC44653.1. Different initiation.
RefSeq	NP_758249.1. NC_004432.1.
3D structure databases
ProteinModelPortal	Q8EUQ9.
ModBase	Search...
Protein family/group databases
MEROPS	M22.001.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1041490.
GenomeReviews	Gene locus MYPE8610 in contig BA000026_GR.
KEGG	mpe:MYPE8610.
NMPDR	fig|272633.1.peg.863.
PATRIC	20020906. VBIMycPen56664_0886.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG304663.
OMA	MEVIGQT.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	MPEN272633:MYPE8610-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_MYCPE

Accession

Primary (citable) accession number: Q8EUQ9

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	September 11, 2007
Last modified:	January 25, 2012
This is version 52 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program