Q8ETN4 (Q8ETN4_OCEIH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Hydroxymethylglutaryl-CoA reductase EMBL BAC12180.1
EC=1.1.1.88 EMBL BAC12180.1

Gene names

Ordered Locus Names:

OB0224

Organism

Oceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE831) [Complete proteome] [HAMAP]

Taxonomic identifier

221109 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Oceanobacillus

Protein attributes

Sequence length	429 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the HMG-CoA reductase family. RuleBase RU004268

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU004269 EMBL BAC12180.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme A metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	coenzyme binding Inferred from electronic annotation. Source: InterPro hydroxymethylglutaryl-CoA reductase (NADPH) activity Inferred from electronic annotation. Source: InterPro hydroxymethylglutaryl-CoA reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8ETN4 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 189B5BE5BDC796D9	FASTA	429	46,259
	10 20 30 40 50 60 MKSSRIPGFY NMSVDQRRKL LKDNYDLTDE QMSNLTDNPS LSLDKADNMI ENVIGTFELP 70 80 90 100 110 120 LGMGLNFVIN GNEYTVPMAI EEASVVASAS HIAKIVRSAG GFEAESRERL MIGQIQVVGC 130 140 150 160 170 180 SNFHEAKQDL LDQKDTLMNA ANDAYPSIVK RGGGTRDLDV RILNEDANST YSQMLVMHIY 190 200 210 220 230 240 VDTCDAMGAN MINTMAEAIA PIVEEITGGK VYLRILSNYA DRSLASAKCV IPPHLLATGD 250 260 270 280 290 300 FTGEEVRDGV IHAYEFAASD PYRAVTHNKG IMNGIDPIVI ATGNDWRAVE AGAHAYAAKD 310 320 330 340 350 360 GQYGSMTRWS RDEAGNLVGE IELPMSVGIV GGATRVHPLA ELSLSIMNIE SAAELAEVIV 370 380 390 400 410 420 SVGLAQNLGA LKALATDGIQ KGHMALHSRS VAIAGGASGE MIDVIAKKLI DQKEIRVGKA KELVEQYKQ

References

[1]	"Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge and its unexpected adaptive capabilities to extreme environments." Takami H., Takaki Y., Uchiyama I. Nucleic Acids Res. 30:3927-3935(2002) [PubMed: 12235376] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 14371 / JCM 11309 / KCTC 3954 / HTE831.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000028 Genomic DNA. Translation: BAC12180.1.
RefSeq	NP_691145.1. NC_004193.1.
3D structure databases
HSSP	HSSP built from PDB template 1QAY based on UniProtKB P13702.
ProteinModelPortal	Q8ETN4.
SMR	Q8ETN4. Positions 3-429.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1015382.
GenomeReviews	Gene locus OB0224 in contig BA000028_GR.
KEGG	oih:OB0224.
NMPDR	fig|221109.1.peg.225.
PATRIC	22791353. VBIOceIhe82024_0230.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG477902.
OMA	NNKGIMN.
PhylomeDB	Q8ETN4.
Enzyme and pathway databases
BioCyc	OIHE221109:OB0224-MONOMER.
Family and domain databases
InterPro	IPR002202. HMG_CoA_Rdtase. IPR004553. HMG_CoA_Rdtase_bac-typ. IPR023074. HMG_CoA_Rdtase_cat. IPR023076. HMG_CoA_Rdtase_CS. IPR009023. HMG_CoA_Rdtase_NAD(P)-bd. IPR009029. HMG_CoA_Rdtase_sub-bd. [Graphical view]
Gene3D	G3DSA:3.30.70.420. G3DSA:3.30.70.420. 1 hit. G3DSA:3.90.770.10. HMG-CoA_red. 2 hits.
KO	K00054.
Pfam	PF00368. HMG-CoA_red. 1 hit. [Graphical view]
SUPFAM	SSF55035. HMG_CoA_NAD_bind. 1 hit. SSF56542. HMG_CoA_sub_bind. 1 hit.
TIGRFAMs	TIGR00532. HMG_CoA_R_NAD. 1 hit.
PROSITE	PS00318. HMG_COA_REDUCTASE_2. 1 hit. PS01192. HMG_COA_REDUCTASE_3. 1 hit. PS50065. HMG_COA_REDUCTASE_4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8ETN4_OCEIH

Accession

Primary (citable) accession number: Q8ETN4

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	December 14, 2011
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)