Q8ETM7 (GLMM_OCEIH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	OB0232

Organism

Oceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE831) [Complete proteome] [HAMAP]

Taxonomic identifier

221109 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Oceanobacillus

Protein attributes

Sequence length	446 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 446	446	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_0000147927
Sites
	Active site	100	1	Phosphoserine intermediate By similarity
	Metal binding	100	1	Magnesium; via phosphate group By similarity
	Metal binding	239	1	Magnesium By similarity
	Metal binding	241	1	Magnesium By similarity
	Metal binding	243	1	Magnesium By similarity
Amino acid modifications
	Modified residue	100	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8ETM7 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 0A2236E82F45DA95	FASTA	446	48,293
	10 20 30 40 50 60 MGKFFGTDGV RGVANEGLTP ELAFKLGRFG GYVLTKDSER PRILIGRDTR VSGHMLEGAL 70 80 90 100 110 120 LAGLLSIGAE VMRLGVISTP GVAYLTKATS AQAGVMISAS HNPVEDNGIK FFGPDGFKLT 130 140 150 160 170 180 DAQENEIESL MEGEDNLPRP TGADIGVVND YFEGGQKYLS YLKDTIDNDF EGIHIAIDCA 190 200 210 220 230 240 NGATSSLATH LFADLEADIY SIGSSPDGLN INDGFGSTHP EKLQEFVVEK NADIGLAFDG 250 260 270 280 290 300 DGDRLIAVDE KGNLVDGDKI MFICAKYMHE IGMLRKDTVV STVMSNLGFY KALENIGLNS 310 320 330 340 350 360 NKTSVGDRYV MEEMRQNGYN LGGEQSGHII FLDYITTGDG MLSAIQLVNV MRETGKPLSE 370 380 390 400 410 420 LADEMVVFPQ VLKNVRVMDK NQALSSSVLL DEVDAVEKEL GEDGRVLVRP SGTEPLVRVM 430 440 VEAKTKEECE QYADRIVSVI EQHLGA

References

[1]

"Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge and its unexpected adaptive capabilities to extreme environments." Takami H., Takaki Y., Uchiyama I. Nucleic Acids Res. 30:3927-3935(2002) [PubMed: 12235376] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 14371 / JCM 11309 / KCTC 3954 / HTE831.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000028 Genomic DNA. Translation: BAC12188.1.
RefSeq	NP_691153.1. NC_004193.1.
3D structure databases
ProteinModelPortal	Q8ETM7.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1015394.
GenomeReviews	Gene locus OB0232 in contig BA000028_GR.
KEGG	oih:OB0232.
NMPDR	fig|221109.1.peg.233.
PATRIC	22791371. VBIOceIhe82024_0239.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG644964.
OMA	PLEDIQV.
PhylomeDB	Q8ETM7.
Enzyme and pathway databases
BioCyc	OIHE221109:OB0232-MONOMER.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_OCEIH

Accession

Primary (citable) accession number: Q8ETM7

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 20, 2005
Last sequence update:	March 1, 2003
Last modified:	January 25, 2012
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program