Q8ET34 (Q8ET34_OCEIH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
3-dehydroquinate dehydratase 1 HAMAP MF_00214
Short name=3-dehydroquinase 1 HAMAP MF_00214
EC=4.2.1.10 HAMAP MF_00214

Alternative name(s):
Type I DHQase 1 HAMAP MF_00214

Gene names

Name:	aroD1 HAMAP MF_00214
Ordered Locus Names:	OB0430

Organism

Oceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE831) [Complete proteome] [HAMAP]

Taxonomic identifier

221109 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Oceanobacillus

Protein attributes

Sequence length	257 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	3-dehydroquinate = 3-dehydroshikimate + H2O. HAMAP MF_00214
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 3/7. HAMAP MF_00214
Subunit structure	Homodimer By similarity. HAMAP MF_00214
Sequence similarities	Belongs to the type-I 3-dehydroquinase family. HAMAP MF_00214

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis HAMAP MF_00214
Ligand	Schiff base HAMAP MF_00214 SAAS SAAS018508
Molecular function	Lyase HAMAP MF_00214 EMBL BAC12386.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	3-dehydroquinate dehydratase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	144	1	Proton acceptor By similarity HAMAP MF_00214
	Active site	171	1	Schiff-base intermediate with substrate By similarity HAMAP MF_00214

Sequences

	Sequence		Length	Mass (Da)
	Q8ET34 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 2593DACA236D123F	FASTA	257	28,519
	10 20 30 40 50 60 MKNVVHVKNI NIGEGKPKVC VPITGATKKE ISEELDLLQT IKVDLVEWRG DLFQEIENEI 70 80 90 100 110 120 SVKNMLQKIN QEIPHLPLLF TFRTKGEGGG REVTLEKYKE INRFVIESKL VDLVDVELFR 130 140 150 160 170 180 GKNLVKELVS FAHLHDQKVI ISNHDFNQTP PRDEIIARLK LAADNGADIG KIAVMPRNDE 190 200 210 220 230 240 DVLNLLSATS LVKELNHIPI VTMSMGADGL ISRLSGEVFG SAITFASGKT ASAPGQIEAE 250 KLQTVLTIIH DSINKKK

References

[1]	"Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge and its unexpected adaptive capabilities to extreme environments." Takami H., Takaki Y., Uchiyama I. Nucleic Acids Res. 30:3927-3935(2002) [PubMed: 12235376] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 14371 / JCM 11309 / KCTC 3954 / HTE831.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000028 Genomic DNA. Translation: BAC12386.1.
RefSeq	NP_691351.1. NC_004193.1.
3D structure databases
HSSP	HSSP built from PDB template 1GQN based on UniProtKB P24670.
ProteinModelPortal	Q8ET34.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1016073.
GenomeReviews	Gene locus OB0430 in contig BA000028_GR.
KEGG	oih:OB0430.
NMPDR	fig|221109.1.peg.436.
PATRIC	22791775. VBIOceIhe82024_0441.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG732926.
OMA	IAKIAVM.
PhylomeDB	Q8ET34.
ProtClustDB	PRK02412.
Enzyme and pathway databases
BioCyc	OIHE221109:OB0430-MONOMER.
Family and domain databases
HAMAP	MF_00214. AroD. [Tree]
InterPro	IPR018508. 3-dehydroquinate_DH_AS. IPR013785. Aldolase_TIM. IPR001381. DHquinase_I. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K03785.
Pfam	PF01487. DHquinase_I. 1 hit. [Graphical view]
TIGRFAMs	TIGR01093. AroD. 1 hit.
PROSITE	PS01028. DEHYDROQUINASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8ET34_OCEIH

Accession

Primary (citable) accession number: Q8ET34

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	December 14, 2011
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)