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Q8ESU8 (ECTB_OCEIH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Diaminobutyrate--2-oxoglutarate transaminase
EC=2.6.1.76
Alternative name(s):
DABA aminotransferase
Diaminobutyrate--2-oxoglutarate aminotransferase
L-2,4-diaminobutyric acid transaminase
Gene names
Name:ectB
Ordered Locus Names:OB0518
OrganismOceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE831) [Complete proteome] [HAMAP]
Taxonomic identifier221109 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Oceanobacillus ›

Protein attributes

Sequence length426 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate By similarity.

Catalytic activity

L-2,4-diaminobutanoate + 2-oxoglutarate = L-aspartate 4-semialdehyde + L-glutamate.

Cofactor

Pyridoxal phosphate By similarity.

Pathway

Amine and polyamine biosynthesis; ectoine biosynthesis; L-ectoine from L-aspartate 4-semialdehyde: step 1/3.

Sequence similarities

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 426426Diaminobutyrate--2-oxoglutarate transaminase
PRO_0000120526

Amino acid modifications

Modified residue2741N6-(pyridoxal phosphate)lysine Potential

Sequences

Sequence LengthMass (Da)Tools
Q8ESU8 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: B966DCD55EB776DC

FASTA42646,943
        10         20         30         40         50         60 
MTTIVDKARN DMAVFEEMES AVRSYSRGWP VVFEKAKGYK LWDKNGNEYI DFFAGAGALN 

        70         80         90        100        110        120 
YGHNPSEMQK VMIDYIQNDG VIHSLDMATA PRKKFLESFN EIILKPRNMD YKVMFPGPTG 

       130        140        150        160        170        180 
TNTVESALKI ARKVTGRDTV IGFTNAFHGM TIGSLSVTGN SFKRNGAGIP LNHAISMPFD 

       190        200        210        220        230        240 
QYVDEQDSIA YIERFLEDSG SGVALPAAFI LETVQGEGGI NAARLEWVKK IEEICRKWDI 

       250        260        270        280        290        300 
LLIIDDVQAG CGRTGTFFSF EEAGINPDIV CLSKSIGGVG LPMAITLIKP EFDQWGPGEH 

       310        320        330        340        350        360 
NGTFRGNNLA FLAATEALNN WKTDAFSQNI KKMSSLFQER MKRIVEKFPE LNADLRGRGL 

       370        380        390        400        410        420 
MLGIGVHVDG LAGEICAEAF SRGLILETSG AKDEVVKFLP PLIIDEDGIE KGMDILEESI 


QAALEK

« Hide

References

[1]"Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge and its unexpected adaptive capabilities to extreme environments."
Takami H., Takaki Y., Uchiyama I.
Nucleic Acids Res. 30:3927-3935(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 14371 / JCM 11309 / KCTC 3954 / HTE831.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000028 Genomic DNA. Translation: BAC12474.1.
RefSeqNP_691439.1. NC_004193.1.

3D structure databases

ProteinModelPortalQ8ESU8.
ModBaseSearch...

Protein-protein interaction databases

STRING221109.OB0518.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAC12474; BAC12474; BAC12474.
GeneID1015788.
KEGGoih:OB0518.
PATRIC22791955. VBIOceIhe82024_0530.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0160.
HOGENOMHOG000020206.
KOK00836.
OMAYSRGWPV.
ProtClustDBPRK09264.

Enzyme and pathway databases

BioCycOIHE221109:GI2A-609-MONOMER.
UniPathwayUPA00067; UER00121.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
3.90.1150.10. 2 hits.
InterProIPR005814. Aminotrans_3.
IPR004637. Dat.
IPR012773. Ectoine_EctB.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERPTHR11986. PTHR11986. 1 hit.
PTHR11986:SF7. PTHR11986:SF7. 1 hit.
PfamPF00202. Aminotran_3. 1 hit.
[Graphical view]
SUPFAMSSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMsTIGR00709. dat. 1 hit.
TIGR02407. ectoine_ectB. 1 hit.
PROSITEPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameECTB_OCEIH
AccessionPrimary (citable) accession number: Q8ESU8
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 2005
Last sequence update: March 1, 2003
Last modified: May 1, 2013
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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