Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8ES94

- PUR5_OCEIH

UniProt

Q8ES94 - PUR5_OCEIH

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Phosphoribosylformylglycinamidine cyclo-ligase

Gene

purM

Organism
Oceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE831)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Purine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciOIHE221109:GI2A-812-MONOMER.
UniPathwayiUPA00074; UER00129.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotation (EC:6.3.3.1UniRule annotation)
Alternative name(s):
AIR synthaseUniRule annotation
AIRSUniRule annotation
Phosphoribosyl-aminoimidazole synthetaseUniRule annotation
Gene namesi
Name:purMUniRule annotation
Ordered Locus Names:OB0747
OrganismiOceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE831)
Taxonomic identifieri221109 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeOceanobacillus
ProteomesiUP000000822: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 339339Phosphoribosylformylglycinamidine cyclo-ligasePRO_0000148227Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi221109.OB0747.

Structurei

3D structure databases

ProteinModelPortaliQ8ES94.
SMRiQ8ES94. Positions 14-338.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the AIR synthase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0150.
HOGENOMiHOG000229091.
KOiK01933.
OMAiVIGKIEH.
OrthoDBiEOG61CM1V.

Family and domain databases

Gene3Di3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPiMF_00741. AIRS.
InterProiIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view]
PfamiPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
SUPFAMiSSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsiTIGR00878. purM. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8ES94-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSEVYKQAGV DVEKGYEAVE RLKKHVARTH RPEVLGGIGA FAGAFDLSSL
60 70 80 90 100
QYKEPVLLSG TDGVGTKLKL AIDLDKHDTV GIDLVAMCVN DIIAQGGDPL
110 120 130 140 150
FFLDYIACGE NDPSRIEAIV SGIAEGCEQA GAALIGGETA EMPGMYDPDE
160 170 180 190 200
YDLAGFVVGI VEKSAMITGK DIKSGDVVIG LSSSGIHSNG YSLVRKLIAD
210 220 230 240 250
VDLNQTYPGL SQTVKDAVMA PTKIYAKSIQ ALKKEVNLKG ISHITGGGFD
260 270 280 290 300
ENIPRMLPDG LGVLIETNSW DIPEVFHFLE EKGNIDNREM YGVFNMGIGM
310 320 330
AVVVAEEDVS IALQLLEKVD EQAYVIGKVT EEEGVHFTL
Length:339
Mass (Da):36,326
Last modified:March 1, 2003 - v1
Checksum:i99DDA067BF24445F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000028 Genomic DNA. Translation: BAC12703.1.
RefSeqiNP_691668.1. NC_004193.1.
WP_011065155.1. NC_004193.1.

Genome annotation databases

EnsemblBacteriaiBAC12703; BAC12703; BAC12703.
GeneIDi1016271.
KEGGioih:OB0747.
PATRICi22792455. VBIOceIhe82024_0763.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000028 Genomic DNA. Translation: BAC12703.1 .
RefSeqi NP_691668.1. NC_004193.1.
WP_011065155.1. NC_004193.1.

3D structure databases

ProteinModelPortali Q8ES94.
SMRi Q8ES94. Positions 14-338.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 221109.OB0747.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAC12703 ; BAC12703 ; BAC12703 .
GeneIDi 1016271.
KEGGi oih:OB0747.
PATRICi 22792455. VBIOceIhe82024_0763.

Phylogenomic databases

eggNOGi COG0150.
HOGENOMi HOG000229091.
KOi K01933.
OMAi VIGKIEH.
OrthoDBi EOG61CM1V.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00129 .
BioCyci OIHE221109:GI2A-812-MONOMER.

Family and domain databases

Gene3Di 3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPi MF_00741. AIRS.
InterProi IPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view ]
Pfami PF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view ]
SUPFAMi SSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsi TIGR00878. purM. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge and its unexpected adaptive capabilities to extreme environments."
    Takami H., Takaki Y., Uchiyama I.
    Nucleic Acids Res. 30:3927-3935(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 14371 / JCM 11309 / KCTC 3954 / HTE831.

Entry informationi

Entry nameiPUR5_OCEIH
AccessioniPrimary (citable) accession number: Q8ES94
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2003
Last sequence update: March 1, 2003
Last modified: October 29, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3