Reviewed, UniProtKB/Swiss-Prot Q8EPW8 (DEOC1_OCEIH)

Names and origin

Protein names

Recommended name:
    Deoxyribose-phosphate aldolase 1
    EC=4.1.2.4
Alternative name(s):
    Phosphodeoxyriboaldolase 1
      Short name=Deoxyriboaldolase 1
      Short name=DERA 1

Gene names

Name:	deoC1
Synonyms:	dra
Ordered Locus Names:	OB1963

Organism

Oceanobacillus iheyensis [Complete proteome] [HAMAP]

Taxonomic identifier

182710 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Oceanobacillus

Protein attributes

Sequence length	221 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. HAMAP MF_00114
Pathway	Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2. HAMAP MF_00114
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Schiff base
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate catabolic process Inferred from electronic annotation. Source: HAMAP deoxyribonucleotide catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	deoxyribose-phosphate aldolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 221	221	Deoxyribose-phosphate aldolase 1 HAMAP MF_00114		PRO_0000057250
Sites
	Active site	152	1	Schiff-base intermediate with acetaldehyde By similarity
	Active site	181	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8EPW8-1 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 81E76D434976E093	FASTA	221	23,666
	10 20 30 40 50 60 MDLAKYIDHT QLKPDTTKQS IVKIVEEAKQ HEFASVCVNP HWVSYCYNEL KDTPVKVCTV 70 80 90 100 110 120 IGFPLGATST ETKIFETNQA IADGATEVDM VINVGELKSN NDAFVEKDIR AVVEAAKGKA 130 140 150 160 170 180 LTKVIIETSL LTEDEKVRAC KLAKNAEADY VKTSTGFSGG GATVEDIRLM RETVGPEMGV 190 200 210 220 KASGGVRDLE QTEAMIEAGA TRIGASSGVA IVSGEQGTSD Y

References

[1]

"Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge and its unexpected adaptive capabilities to extreme environments." Takami H., Takaki Y., Uchiyama I. Nucleic Acids Res. 30:3927-3935(2002) [PubMed: 12235376] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 14371 / JCM 11309 / KCTC 3954 / HTE831.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000028 Genomic DNA. Translation: BAC13919.1.
RefSeq	NP_692884.1.
3D structure databases
HSSP	HSSP built from PDB template 1O0Y based on UniProtKB Q9X1P5.
ModBase	Search...
Genome annotation databases
GeneID	1018440.
GenomeReviews	Gene locus OB1963 in contig BA000028_GR.
KEGG	oih:OB1963.
NMPDR	fig|221109.1.peg.1963.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8EPW8.
OMA	AKMIDHT.
Enzyme and pathway databases
BioCyc	OIHE221109:OB1963-MON.
BRENDA	4.1.2.4. 278212.
Family and domain databases
HAMAP	MF_00114. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR011343. DeoC. IPR002915. DeoC/AroFGH_arch. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
PANTHER	PTHR10889. DeoC. 1 hit.
Pfam	PF01791. DeoC. 1 hit. [Graphical view]
PIRSF	PIRSF001357. DeoC. 1 hit.
TIGRFAMs	TIGR00126. deoC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DEOC1_OCEIH

Accession

Primary (citable) accession number: Q8EPW8

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 14, 2003
Last sequence update:	March 1, 2003
Last modified:	November 3, 2009
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)