Reviewed, UniProtKB/Swiss-Prot Q8EPB4 (PPNK2_OCEIH)

Names and origin

Protein names

Recommended name:
    Probable inorganic polyphosphate/ATP-NAD kinase 2
      Short name=Poly(P)/ATP NAD kinase 2
    EC=2.7.1.23

Gene names

Name:	ppnK2
Ordered Locus Names:	OB2196

Organism

Oceanobacillus iheyensis [Complete proteome] [HAMAP]

Taxonomic identifier

182710 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Oceanobacillus

Protein attributes

Sequence length	266 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity.
Catalytic activity	ATP + NAD+ = ADP + NADP+. HAMAP MF_00361
Cofactor	Divalent metal ions By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the NAD kinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding NAD NADP Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW NAD+ kinase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 266	266	Probable inorganic polyphosphate/ATP-NAD kinase 2 HAMAP MF_00361		PRO_0000120643

Sequences

	Sequence		Length	Mass (Da)
	Q8EPB4-1 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: FCF1BD5DF6AB442C	FASTA	266	30,030
	10 20 30 40 50 60 MAERQNIFFY YHPDEEMDGK VKALKKISSE NGLNVVENSS DASIIVSIGG DGTFLQAVRK 70 80 90 100 110 120 TGFRQDCIYT GIMREGQSGL YCDFNIDNFD NMIHSVLHED LEVRRFPTIK VQINGETPFY 130 140 150 160 170 180 CLNEVSIRST IVKTIVINVC VDGFHFETFR GDGMIVSTPT GSTGYSKSAR GAVIDPLIHG 190 200 210 220 230 240 FQVSEVASLN NNQYRTLGSS FLLNKDRKLE LEILQDGNDH PIISLDNEAS PIKRIQNIDV 250 260 TMDETIIKTV KLKNNSYWER VKRTFL

References

[1]

"Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge and its unexpected adaptive capabilities to extreme environments." Takami H., Takaki Y., Uchiyama I. Nucleic Acids Res. 30:3927-3935(2002) [PubMed: 12235376] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 14371 / JCM 11309 / KCTC 3954 / HTE831.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000028 Genomic DNA. Translation: BAC14152.1.
RefSeq	NP_693117.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1015552.
GenomeReviews	Gene locus OB2196 in contig BA000028_GR.
KEGG	oih:OB2196.
NMPDR	fig|221109.1.peg.2194.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8EPB4.
OMA	Q8EPB4. NEVSIRS.
Enzyme and pathway databases
BioCyc	OIHE221109:OB2196-MON.
BRENDA	2.7.1.23. 278212.
Family and domain databases
HAMAP	MF_00361. [Tree]
InterPro	IPR017437. ATP-NAD_kinase_PpnK-typ_all-b. IPR002504. ATP_NADK. [Graphical view]
Gene3D	G3DSA:2.60.200.30. ATP-NAD_kinase_PpnK-typ. 1 hit.
PANTHER	PTHR20275. ATP_NADK. 1 hit.
Pfam	PF01513. NAD_kinase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PPNK2_OCEIH

Accession

Primary (citable) accession number: Q8EPB4

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 22, 2003
Last sequence update:	March 1, 2003
Last modified:	June 16, 2009
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)