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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. ATP-dependent 6-phosphofructokinase (pfkA)
  4. Fructose-bisphosphate aldolase class 1 (fda)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei290Proton donorUniRule annotation1
Active sitei311UniRule annotation1
Active sitei425UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processGluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciOIHE221109:G1G3F-2439-MONOMER
UniPathwayiUPA00109; UER00181

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:OB2336
OrganismiOceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831)
Taxonomic identifieri221109 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeOceanobacillus
Proteomesi
  • UP000000822 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001806971 – 448Glucose-6-phosphate isomeraseAdd BLAST448

Proteomic databases

PRIDEiQ8ENY8

Interactioni

Protein-protein interaction databases

STRINGi221109.OB2336

Structurei

3D structure databases

ProteinModelPortaliQ8ENY8
SMRiQ8ENY8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QYV Bacteria
COG0166 LUCA
HOGENOMiHOG000100403
KOiK01810
OMAiVERCKAM
OrthoDBiPOG091H0EIM

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 1 hit
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00765 P_GLUCOSE_ISOMERASE_1, 1 hit
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q8ENY8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTHVSFNYEK ALSFFEKQEI TNLEPFVHTA HQMIHERIGA GKDFLGWLDL
60 70 80 90 100
PRNYNREEYT RIKAAADKIK KDSDILLVIG IGGSYLGAKA ALEMLNHSFQ
110 120 130 140 150
NLLSKDQRQV PQIIFVGHHL SSTYMTELFD ILKDKDFSIN VISKSGTTTE
160 170 180 190 200
PAIAFRVFKK YLEEKYGQDE AKKRIYATTD RSKGALKTTA DSNDYETFVI
210 220 230 240 250
PDDVGGRYSV LTAVGLLPIA ASGINIDDMM EGAKAGMEDL ANPVISENPA
260 270 280 290 300
YQYAAVRNIL YQKGKVTELL INYEPNLQYF SEWWKQLFGE SEGKNQKGIY
310 320 330 340 350
PSSANFTTDL HSLGQYIQEG RRNIFETILH VNEPKKDFTL EKEESDLDGL
360 370 380 390 400
NYLAGKSIHE INDKAFQGTL LAHTDGDVPN LIVEVPRLDA YTFGYLVYFF
410 420 430 440
EKACAISGYI LGVNPFDQPG VEAYKKNMFA LLGKPGFEDQ KEALEKRL
Length:448
Mass (Da):50,592
Last modified:March 1, 2003 - v1
Checksum:i1374AD7454C17F89
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000028 Genomic DNA Translation: BAC14292.1
RefSeqiWP_011066729.1, NC_004193.1

Genome annotation databases

EnsemblBacteriaiBAC14292; BAC14292; BAC14292
KEGGioih:OB2336

Similar proteinsi

Entry informationi

Entry nameiG6PI_OCEIH
AccessioniPrimary (citable) accession number: Q8ENY8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 23, 2003
Last sequence update: March 1, 2003
Last modified: March 28, 2018
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome