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Q8EN87 (MTLD_OCEIH) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Mannitol-1-phosphate 5-dehydrogenase
EC=1.1.1.17
Gene names
Name:mtlD
Ordered Locus Names:OB2600
OrganismOceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE831) [Complete proteome] [HAMAP]
Taxonomic identifier221109 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Oceanobacillus

Protein attributes

Sequence length386 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH. HAMAP MF_00196

Sequence similarities

Belongs to the mannitol dehydrogenase family.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functioncoenzyme binding

Inferred from electronic annotation. Source: InterPro

mannitol-1-phosphate 5-dehydrogenase activity

Inferred from electronic annotation. Source: EC

nucleotide binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 386386Mannitol-1-phosphate 5-dehydrogenase HAMAP MF_00196
PRO_0000170714

Regions

Nucleotide binding4 – 1512NAD By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8EN87 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 151842F9E829C594

FASTA38643,089
        10         20         30         40         50         60 
MKTAVHFGAG NIGRGFIGLL LYQSGYQTIF IDVNNQVIDE INKQKSYHVY LAGKEKQELT 

        70         80         90        100        110        120 
VNHITGINSI KEPDAVTEAI VKADVVTTAV GPTILPVIAK AISKGLQERT KQNNSPLNII 

       130        140        150        160        170        180 
ACENMVGGSS LLKEHVFESL EAHKIGEFDR LYGFPDAAVD RIVPNQTNKN LLDVMVEPYY 

       190        200        210        220        230        240 
EWVVEKKKIV GEVPPIFGIT YVDDLAPYIE RKLFTVNTGH AIPAYLGTHL GYDTIVEAMK 

       250        260        270        280        290        300 
DLRIDDTIYG ALAESGEALI HAYGFNREMH QEYVSKIIQR FQNPYISDDV KRVARGPIRK 

       310        320        330        340        350        360 
LGAKDRLVKP ALMYIEYTGK IPVYLAKTIA AALLFNNDED REAIELQKKI SATGYQQAFV 

       370        380 
EVSGCDSDSI LTKKVIEQLR LLQNKK

« Hide

References

[1]"Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge and its unexpected adaptive capabilities to extreme environments."
Takami H., Takaki Y., Uchiyama I.
Nucleic Acids Res. 30:3927-3935(2002) [PubMed: 12235376] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 14371 / JCM 11309 / KCTC 3954 / HTE831.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000028 Genomic DNA. Translation: BAC14556.1.
RefSeqNP_693521.1. NC_004193.1.

3D structure databases

ProteinModelPortalQ8EN87.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1017095.
GenomeReviewsGene locus OB2600 in contig BA000028_GR.
KEGGoih:OB2600.
NMPDRfig|221109.1.peg.2599.
PATRIC22796266. VBIOceIhe82024_2637.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG568825.
OMAFANTAVD.
PhylomeDBQ8EN87.
ProtClustDBPRK02318.

Enzyme and pathway databases

BioCycOIHE221109:OB2600-MONOMER.

Family and domain databases

HAMAPMF_00196. Mannitol_dehydrog.
[Tree]
InterProIPR008927. 6-PGluconate_DH_C-like.
IPR013328. DH_multihelical.
IPR023028. Mannitol_1_phos_5_DH.
IPR000669. Mannitol_DH.
IPR013118. Mannitol_DH_C.
IPR023027. Mannitol_DH_CS.
IPR013131. Mannitol_DH_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
G3DSA:1.10.1040.10. Opine_DH. 1 hit.
KOK00009.
PfamPF01232. Mannitol_dh. 1 hit.
PF08125. Mannitol_dh_C. 1 hit.
[Graphical view]
PRINTSPR00084. MTLDHDRGNASE.
SUPFAMSSF48179. 6DGDH_C_like. 1 hit.
PROSITEPS00974. MANNITOL_DHGENASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMTLD_OCEIH
AccessionPrimary (citable) accession number: Q8EN87
Entry history
Integrated into UniProtKB/Swiss-Prot: April 23, 2003
Last sequence update: March 1, 2003
Last modified: January 25, 2012
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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