Reviewed, UniProtKB/Swiss-Prot Q8EMT9 (DEOC2_OCEIH)

Names and origin

Protein names

Recommended name:
    Deoxyribose-phosphate aldolase 2
    EC=4.1.2.4
Alternative name(s):
    Phosphodeoxyriboaldolase 2
      Short name=Deoxyriboaldolase 2
      Short name=DERA 2

Gene names

Name:	deoC2
Ordered Locus Names:	OB2751

Organism

Oceanobacillus iheyensis [Complete proteome] [HAMAP]

Taxonomic identifier

182710 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Oceanobacillus

Protein attributes

Sequence length	223 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. HAMAP MF_00114
Pathway	Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2. HAMAP MF_00114
Subcellular location	Cytoplasm By similarity HAMAP MF_00114.
Sequence similarities	Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Schiff base
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate catabolic process Inferred from electronic annotation. Source: HAMAP deoxyribonucleotide catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	deoxyribose-phosphate aldolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 223	223	Deoxyribose-phosphate aldolase 2 HAMAP MF_00114		PRO_0000057251
Sites
	Active site	154	1	Schiff-base intermediate with acetaldehyde By similarity
	Active site	183	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8EMT9-1 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: E08E223F6B5CD19C	FASTA	223	23,892
	10 20 30 40 50 60 MEKRELVNII DYTLLHPTAN KADIESFLQE VVNYGFKTIF VQPYFVPFAV NWLADHDVNV 70 80 90 100 110 120 GVPVGFSLGG ATTHVKVEET KEAIRNGAKE IDMLVNLGAL KSGDYQMVET DIAKVVEAAN 130 140 150 160 170 180 GLNTKVIIET ALLNQEEKIS VTECIIRAGA DFVKTATGFN GGGATVEDVR LLNEIGKGKI 190 200 210 220 QVKAAGGIKT YEDALAIIDA GATRIGSSGA IQIIRGETST SSY

References

[1]

"Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge and its unexpected adaptive capabilities to extreme environments." Takami H., Takaki Y., Uchiyama I. Nucleic Acids Res. 30:3927-3935(2002) [PubMed: 12235376] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 14371 / JCM 11309 / KCTC 3954 / HTE831.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000028 Genomic DNA. Translation: BAC14707.1.
RefSeq	NP_693673.1.
3D structure databases
SMR	Q8EMT9. Positions 2-219.
ModBase	Search...
Genome annotation databases
GeneID	1016999.
GenomeReviews	Gene locus OB2751 in contig BA000028_GR.
KEGG	oih:OB2751.
NMPDR	fig|221109.1.peg.2751.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG636421.
OMA	LAKDDIN.
Enzyme and pathway databases
BioCyc	OIHE221109:OB2751-MONOMER.
BRENDA	4.1.2.4. 278212.
Family and domain databases
HAMAP	MF_00114. DeoC_type1. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR011343. DeoC. IPR002915. DeoC/AroFGH_arch. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
PANTHER	PTHR10889. DeoC. 1 hit.
Pfam	PF01791. DeoC. 1 hit. [Graphical view]
PIRSF	PIRSF001357. DeoC. 1 hit.
TIGRFAMs	TIGR00126. deoC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DEOC2_OCEIH

Accession

Primary (citable) accession number: Q8EMT9

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 14, 2003
Last sequence update:	March 1, 2003
Last modified:	February 9, 2010
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)