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Q8EM45 (SYR_OCEIH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:OB3015
OrganismOceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE831) [Complete proteome] [HAMAP]
Taxonomic identifier221109 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeOceanobacillus

Protein attributes

Sequence length556 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 556556Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000151585

Regions

Motif132 – 14211"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q8EM45 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 39D99952AC2C3005

FASTA55662,504
        10         20         30         40         50         60 
MNVLEQTEQK LKEQIHHAVI HAELATEDQV PDIILEKPKD KAHGDFATNI AMQLARVAKK 

        70         80         90        100        110        120 
APRQIADDIA SKLNKSEASV EKVEIAGPGF INFFMKQDFL GEVIDTVLSA GDNYGKSTGG 

       130        140        150        160        170        180 
NGEKVQVEFV SVNPTGDLHL GHARNAAFGD VLCNVFAAAG YEVEREYYIN DAGNQINNLG 

       190        200        210        220        230        240 
LSVEARYLQE IGQDVDMPED GYQGQAIIEI AKELVKKDGE KWADKDHEER LDFFKEYGLK 

       250        260        270        280        290        300 
ASLRNIESDL KDFRVEFDHW FSERSLFKDG QIDDTLAVLD DGGYTFEKDG ALWFKTTEFG 

       310        320        330        340        350        360 
DDKDRVLIKG DGNYTYLTPD IAYHKNKLDR GFDRIINVWG SDHHGYIPRM RAALQALGYP 

       370        380        390        400        410        420 
VEKFDVKIIQ MVNLFEAGEK VKMSKRTGKA VSLRELMDEV GIDAVRYYFV ARSNDSQLDF 

       430        440        450        460        470        480 
DMDLAKSQSN DNPVYYAQYA HARICTMLSQ AKSKGFNTEA EFDASLLTAE KELDLLKKIG 

       490        500        510        520        530        540 
ELPQMIVDAA DKHTPHKVTQ YIFELATLLH SFYNAEKVLD ADNEARTHAR IALMKAVRQT 

       550 
LANAMTIIGI SAPEKM 

« Hide

References

[1]"Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge and its unexpected adaptive capabilities to extreme environments."
Takami H., Takaki Y., Uchiyama I.
Nucleic Acids Res. 30:3927-3935(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 14371 / JCM 11309 / KCTC 3954 / HTE831.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000028 Genomic DNA. Translation: BAC14971.1.
RefSeqNP_693937.1. NC_004193.1.

3D structure databases

ProteinModelPortalQ8EM45.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING221109.OB3015.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAC14971; BAC14971; BAC14971.
GeneID1016713.
KEGGoih:OB3015.
PATRIC22797118. VBIOceIhe82024_3063.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMAMEHMGFG.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycOIHE221109:GI2A-3104-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_OCEIH
AccessionPrimary (citable) accession number: Q8EM45
Entry history
Integrated into UniProtKB/Swiss-Prot: November 14, 2003
Last sequence update: March 1, 2003
Last modified: May 14, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries