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Q8ELI2

- ALF1_OCEIH

UniProt

Q8ELI2 - ALF1_OCEIH

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Protein

Fructose-bisphosphate aldolase class 1

Gene

fda

Organism
Oceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE831)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei176 – 1761Proton acceptorUniRule annotation
Active sitei213 – 2131Schiff-base intermediate with dihydroxyacetone-PUniRule annotation

GO - Molecular functioni

  1. fructose-bisphosphate aldolase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

Schiff base

Enzyme and pathway databases

BioCyciOIHE221109:GI2A-3334-MONOMER.
UniPathwayiUPA00109; UER00183.

Names & Taxonomyi

Protein namesi
Recommended name:
Fructose-bisphosphate aldolase class 1UniRule annotation (EC:4.1.2.13UniRule annotation)
Alternative name(s):
Fructose-bisphosphate aldolase class I
Short name:
FBP aldolaseUniRule annotation
Gene namesi
Name:fdaUniRule annotation
Ordered Locus Names:OB3245
OrganismiOceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE831)
Taxonomic identifieri221109 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeOceanobacillus
ProteomesiUP000000822: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 294294Fructose-bisphosphate aldolase class 1PRO_0000216901Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi221109.OB3245.

Structurei

3D structure databases

ProteinModelPortaliQ8ELI2.
SMRiQ8ELI2. Positions 1-294.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class I fructose-bisphosphate aldolase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG3588.
HOGENOMiHOG000073502.
KOiK01623.
OMAiYTGDYLA.
OrthoDBiEOG6M6JJT.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00729. FBP_aldolase_1.
InterProiIPR013785. Aldolase_TIM.
IPR000741. FBA_I.
IPR023014. FBA_I_Gram+-type.
[Graphical view]
PfamiPF00274. Glycolytic. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8ELI2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNQKQLEQMK TSKGFIAALD QSGGSTPKAL AAYGIPEDSY NNEDEMFDLV
60 70 80 90 100
HEMRTRIITS KAFDSDSIIG AILFEQTMDR EIEGMYTGDY LAEKKGIVPF
110 120 130 140 150
LKVDKGLAEE TNGVQLMKPI DNLDETLRRA NERNIFGTKM RSVIKQANPK
160 170 180 190 200
AIKEVVDQQF DIGKKIIAAG LVPIIEPEVD IHSPEKEKCE DLLKAEIINH
210 220 230 240 250
LNQLSEDENV MLKLTIPTKK NLYKELIDHP RVVRVVALSG GYSTDVANEK
260 270 280 290
LKENNGLIAS FSRALSQDLN ADQSDEDFNL ALEKAVKSIY DASV
Length:294
Mass (Da):32,819
Last modified:March 1, 2003 - v1
Checksum:i76B018EE93174698
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000028 Genomic DNA. Translation: BAC15201.1.
RefSeqiNP_694167.1. NC_004193.1.

Genome annotation databases

EnsemblBacteriaiBAC15201; BAC15201; BAC15201.
GeneIDi1016498.
KEGGioih:OB3245.
PATRICi22797586. VBIOceIhe82024_3297.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000028 Genomic DNA. Translation: BAC15201.1 .
RefSeqi NP_694167.1. NC_004193.1.

3D structure databases

ProteinModelPortali Q8ELI2.
SMRi Q8ELI2. Positions 1-294.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 221109.OB3245.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAC15201 ; BAC15201 ; BAC15201 .
GeneIDi 1016498.
KEGGi oih:OB3245.
PATRICi 22797586. VBIOceIhe82024_3297.

Phylogenomic databases

eggNOGi COG3588.
HOGENOMi HOG000073502.
KOi K01623.
OMAi YTGDYLA.
OrthoDBi EOG6M6JJT.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00183 .
BioCyci OIHE221109:GI2A-3334-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00729. FBP_aldolase_1.
InterProi IPR013785. Aldolase_TIM.
IPR000741. FBA_I.
IPR023014. FBA_I_Gram+-type.
[Graphical view ]
Pfami PF00274. Glycolytic. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge and its unexpected adaptive capabilities to extreme environments."
    Takami H., Takaki Y., Uchiyama I.
    Nucleic Acids Res. 30:3927-3935(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 14371 / JCM 11309 / KCTC 3954 / HTE831.

Entry informationi

Entry nameiALF1_OCEIH
AccessioniPrimary (citable) accession number: Q8ELI2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 21, 2003
Last sequence update: March 1, 2003
Last modified: October 1, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3