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Q8ELI2

- ALF1_OCEIH

UniProt

Q8ELI2 - ALF1_OCEIH

Protein

Fructose-bisphosphate aldolase class 1

Gene

fda

Organism
Oceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE831)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 66 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei176 – 1761Proton acceptorUniRule annotation
    Active sitei213 – 2131Schiff-base intermediate with dihydroxyacetone-PUniRule annotation

    GO - Molecular functioni

    1. fructose-bisphosphate aldolase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Lyase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    Schiff base

    Enzyme and pathway databases

    BioCyciOIHE221109:GI2A-3334-MONOMER.
    UniPathwayiUPA00109; UER00183.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Fructose-bisphosphate aldolase class 1UniRule annotation (EC:4.1.2.13UniRule annotation)
    Alternative name(s):
    Fructose-bisphosphate aldolase class I
    Short name:
    FBP aldolaseUniRule annotation
    Gene namesi
    Name:fdaUniRule annotation
    Ordered Locus Names:OB3245
    OrganismiOceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE831)
    Taxonomic identifieri221109 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeOceanobacillus
    ProteomesiUP000000822: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 294294Fructose-bisphosphate aldolase class 1PRO_0000216901Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi221109.OB3245.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8ELI2.
    SMRiQ8ELI2. Positions 1-294.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the class I fructose-bisphosphate aldolase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG3588.
    HOGENOMiHOG000073502.
    KOiK01623.
    OMAiYTGDYLA.
    OrthoDBiEOG6M6JJT.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_00729. FBP_aldolase_1.
    InterProiIPR013785. Aldolase_TIM.
    IPR000741. FBA_I.
    IPR023014. FBA_I_Gram+-type.
    [Graphical view]
    PfamiPF00274. Glycolytic. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8ELI2-1 [UniParc]FASTAAdd to Basket

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    MNQKQLEQMK TSKGFIAALD QSGGSTPKAL AAYGIPEDSY NNEDEMFDLV    50
    HEMRTRIITS KAFDSDSIIG AILFEQTMDR EIEGMYTGDY LAEKKGIVPF 100
    LKVDKGLAEE TNGVQLMKPI DNLDETLRRA NERNIFGTKM RSVIKQANPK 150
    AIKEVVDQQF DIGKKIIAAG LVPIIEPEVD IHSPEKEKCE DLLKAEIINH 200
    LNQLSEDENV MLKLTIPTKK NLYKELIDHP RVVRVVALSG GYSTDVANEK 250
    LKENNGLIAS FSRALSQDLN ADQSDEDFNL ALEKAVKSIY DASV 294
    Length:294
    Mass (Da):32,819
    Last modified:March 1, 2003 - v1
    Checksum:i76B018EE93174698
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000028 Genomic DNA. Translation: BAC15201.1.
    RefSeqiNP_694167.1. NC_004193.1.

    Genome annotation databases

    EnsemblBacteriaiBAC15201; BAC15201; BAC15201.
    GeneIDi1016498.
    KEGGioih:OB3245.
    PATRICi22797586. VBIOceIhe82024_3297.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000028 Genomic DNA. Translation: BAC15201.1 .
    RefSeqi NP_694167.1. NC_004193.1.

    3D structure databases

    ProteinModelPortali Q8ELI2.
    SMRi Q8ELI2. Positions 1-294.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 221109.OB3245.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAC15201 ; BAC15201 ; BAC15201 .
    GeneIDi 1016498.
    KEGGi oih:OB3245.
    PATRICi 22797586. VBIOceIhe82024_3297.

    Phylogenomic databases

    eggNOGi COG3588.
    HOGENOMi HOG000073502.
    KOi K01623.
    OMAi YTGDYLA.
    OrthoDBi EOG6M6JJT.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00183 .
    BioCyci OIHE221109:GI2A-3334-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_00729. FBP_aldolase_1.
    InterProi IPR013785. Aldolase_TIM.
    IPR000741. FBA_I.
    IPR023014. FBA_I_Gram+-type.
    [Graphical view ]
    Pfami PF00274. Glycolytic. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge and its unexpected adaptive capabilities to extreme environments."
      Takami H., Takaki Y., Uchiyama I.
      Nucleic Acids Res. 30:3927-3935(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 14371 / JCM 11309 / KCTC 3954 / HTE831.

    Entry informationi

    Entry nameiALF1_OCEIH
    AccessioniPrimary (citable) accession number: Q8ELI2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 21, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 66 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3