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Protein

Putative modification methylase OB3336

Gene

OB3336

Organism
Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

This methylase recognizes the double-stranded sequence ACCGGT, causes specific methylation on C-? on both strands, and protects the DNA from cleavage by a specific endonuclease.Curated

Catalytic activityi

S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei97PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferase, Transferase
Biological processRestriction system
LigandS-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciOIHE221109:G1G3F-3444-MONOMER

Protein family/group databases

REBASEi6390 M.OihORF3336P

Names & Taxonomyi

Protein namesi
Recommended name:
Putative modification methylase OB3336 (EC:2.1.1.37)
Alternative name(s):
Cytosine-specific methyltransferase
M.OihORF3336P
Gene namesi
Ordered Locus Names:OB3336
OrganismiOceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831)
Taxonomic identifieri221109 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeOceanobacillus
Proteomesi
  • UP000000822 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000879151 – 460Putative modification methylase OB3336Add BLAST460

Interactioni

Protein-protein interaction databases

STRINGi221109.OB3336

Structurei

3D structure databases

ProteinModelPortaliQ8EL95
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 458SAM-dependent MTase C5-typePROSITE-ProRule annotationAdd BLAST444

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105DVF Bacteria
COG0270 LUCA
HOGENOMiHOG000225505
KOiK00558
OMAiFPDNYFF
OrthoDBiPOG091H02EL

Family and domain databases

InterProiView protein in InterPro
IPR001525 C5_MeTfrase
IPR031303 C5_meth_CS
IPR029063 SAM-dependent_MTases
PfamiView protein in Pfam
PF00145 DNA_methylase, 1 hit
PRINTSiPR00105 C5METTRFRASE
SUPFAMiSSF53335 SSF53335, 2 hits
TIGRFAMsiTIGR00675 dcm, 1 hit
PROSITEiView protein in PROSITE
PS00095 C5_MTASE_2, 1 hit
PS51679 SAM_MT_C5, 1 hit

Sequencei

Sequence statusi: Complete.

Q8EL95-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHQIYSATST DKKLPEVVDL FSGCGGLALG FQLAGFNIRK GIELDRDASD
60 70 80 90 100
VASFNLHWRQ GKHDRHLNND ITLLSANEFY NDLDRKNDLI VIGGPPCQAY
110 120 130 140 150
SKIGRAKLKS LGEERRQEND ARGKLYENFL DYALHVDANV IVMENVPEAV
160 170 180 190 200
NYGGVNIPDT VCDILINKGY DAIWTVLNAA DFGVPQTRVR LFVMAIKKDI
210 220 230 240 250
GKIKFIPEPT HKPHINVKRQ SVNVRWMQSE IRNSKYYKQP NIPDETLSDW
260 270 280 290 300
VTVGDAIGDL PNLFPVYNQK YKNYKPMMMK EYKSPPQNTF QKLMRINNKV
310 320 330 340 350
DKVTGNMFRN TKRDFSIFDK MEEGDNYLDA HNIAMSLLRK EMRKSGITKE
360 370 380 390 400
NEFEYRLLKD RIVPPYSTEK FVEKWRKLSS DKPSHTLVAH LSTDTYSHLH
410 420 430 440 450
PREPRGISVR EAARLQSFPD DFLFDCSMGA AFKQIGNAVP PLLAKAIAEA
460
MKKNIQGGCI
Length:460
Mass (Da):52,508
Last modified:March 1, 2003 - v1
Checksum:i5483B86933CDBD0C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000028 Genomic DNA Translation: BAC15292.1
RefSeqiWP_011067734.1, NC_004193.1

Genome annotation databases

EnsemblBacteriaiBAC15292; BAC15292; BAC15292
KEGGioih:OB3336

Similar proteinsi

Entry informationi

Entry nameiMT36_OCEIH
AccessioniPrimary (citable) accession number: Q8EL95
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 30, 2004
Last sequence update: March 1, 2003
Last modified: March 28, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health