Q8EL21 (UXUA_OCEIH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Mannonate dehydratase
EC=4.2.1.8

Alternative name(s):
D-mannonate hydrolase

Gene names

Name:	uxuA
Ordered Locus Names:	OB3411

Organism

Oceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE831) [Complete proteome] [HAMAP]

Taxonomic identifier

221109 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Oceanobacillus

Protein attributes

Sequence length	349 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O. HAMAP MF_00106
Pathway	Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP MF_00106
Sequence similarities	Belongs to the mannonate dehydratase family.

Ontologies

Keywords
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glucuronate catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	mannonate dehydratase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 349	349	Mannonate dehydratase HAMAP MF_00106		PRO_0000170678

Sequences

	Sequence		Length	Mass (Da)
	Q8EL21 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: BE4AA663A19F2F8C	FASTA	349	39,850
	10 20 30 40 50 60 MQLSFRWYGD SDPVTLKQIK QIPDMKHIVS AIYDVPVGDV WTKDKINALK SSIEQEGLTL 70 80 90 100 110 120 SVMESLPVHE SIKLGEANRD NLIENYKKSL RNLGESGIKT VCYNFMPVFD WTRSNLDYEL 130 140 150 160 170 180 EDGSKTLMYD NDFVKDIDPV TTNLNLPGWD ESYTKEEMAT LIEKYRQFDE EDLWKNLEYF 190 200 210 220 230 240 LNAVLPIAIE HDIDLTIHPD DPPWSIFGIP RIIKTKESYQ RLIAINSSKN NGICFCTGSL 250 260 270 280 290 300 GCLEENDLPE IIKEFGDHIH FVHMRNIKRL DNHSFVESGH LSKYGSVDMK AVVRALKDIN 310 320 330 340 YKGTIRPDHG RMIWGETGKA GYGLFDRALG ATYINGLIEG VETNDTTIS

References

[1]

"Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge and its unexpected adaptive capabilities to extreme environments." Takami H., Takaki Y., Uchiyama I. Nucleic Acids Res. 30:3927-3935(2002) [PubMed: 12235376] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 14371 / JCM 11309 / KCTC 3954 / HTE831.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000028 Genomic DNA. Translation: BAC15367.1.
RefSeq	NP_694333.1. NC_004193.1.
3D structure databases
ProteinModelPortal	Q8EL21.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1016219.
GenomeReviews	Gene locus OB3411 in contig BA000028_GR.
KEGG	oih:OB3411.
NMPDR	fig|221109.1.peg.3415.
PATRIC	22797928. VBIOceIhe82024_3468.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG585927.
OMA	IWETLEK.
PhylomeDB	Q8EL21.
ProtClustDB	PRK03906.
Enzyme and pathway databases
BioCyc	OIHE221109:OB3411-MONOMER.
Family and domain databases
HAMAP	MF_00106. UxuA. [Tree]
InterPro	IPR004628. Man_deHydtase. IPR013022. Xyl_isomerase-like_TIM-brl. [Graphical view]
Gene3D	G3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
KO	K01686.
Pfam	PF03786. UxuA. 1 hit. [Graphical view]
PIRSF	PIRSF016049. Man_dehyd. 1 hit.
SUPFAM	SSF51658. Xyl_isomerase-like_TIM-brl. 1 hit.
TIGRFAMs	TIGR00695. UxuA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

UXUA_OCEIH

Accession

Primary (citable) accession number: Q8EL21

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 11, 2003
Last sequence update:	March 1, 2003
Last modified:	January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program