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Protein
Submitted name:

Glutathione uptake transporter

Gene

SO_0002

Organism
Shewanella oneidensis (strain MR-1)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

TransportUniRule annotation

Protein family/group databases

TCDBi2.A.17.4.7. the proton-dependent oligopeptide transporter (pot/ptr) family.

Names & Taxonomyi

Protein namesi
Submitted name:
Glutathione uptake transporterImported
Gene namesi
Ordered Locus Names:SO_0002Imported
OrganismiShewanella oneidensis (strain MR-1)Imported
Taxonomic identifieri211586 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
Proteomesi
  • UP000008186 Componenti: Chromosome

Subcellular locationi

  • Membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei26 – 4722HelicalSequence analysisAdd
BLAST
Transmembranei59 – 7820HelicalSequence analysisAdd
BLAST
Transmembranei85 – 10521HelicalSequence analysisAdd
BLAST
Transmembranei111 – 13020HelicalSequence analysisAdd
BLAST
Transmembranei178 – 19720HelicalSequence analysisAdd
BLAST
Transmembranei233 – 25018HelicalSequence analysisAdd
BLAST
Transmembranei256 – 27823HelicalSequence analysisAdd
BLAST
Transmembranei298 – 31518HelicalSequence analysisAdd
BLAST
Transmembranei342 – 36322HelicalSequence analysisAdd
BLAST
Transmembranei375 – 39723HelicalSequence analysisAdd
BLAST
Transmembranei409 – 43123HelicalSequence analysisAdd
BLAST
Transmembranei443 – 46220HelicalSequence analysisAdd
BLAST
Transmembranei482 – 50322HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ8EKT7.

Interactioni

Protein-protein interaction databases

STRINGi211586.SO_0002.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2XUTX-ray3.62A/B/C1-516[»]
4UVMX-ray3.00A4-516[»]
ProteinModelPortaliQ8EKT7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PTR2/POT transporter (TC 2.A.17) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG4105DUX. Bacteria.
COG3104. LUCA.
HOGENOMiHOG000285186.
KOiK03305.
OMAiVTAFQMF.
OrthoDBiEOG69971K.
PhylomeDBiQ8EKT7.

Family and domain databases

InterProiIPR005279. Dipep/tripep_permease.
IPR020846. MFS_dom.
IPR000109. POT_fam.
IPR018456. PTR2_symporter_CS.
[Graphical view]
PANTHERiPTHR11654. PTHR11654. 2 hits.
PfamiPF00854. PTR2. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 2 hits.
TIGRFAMsiTIGR00924. yjdL_sub1_fam. 1 hit.
PROSITEiPS01022. PTR2_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8EKT7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTPVDAPKW PRQIPYIIAS EACERFSFYG MRNILTPFLM TALLLSIPEE
60 70 80 90 100
LRGAVAKDVF HSFVIGVYFF PLLGGWIADR FFGKYNTILW LSLIYCVGHA
110 120 130 140 150
FLAIFEHSVQ GFYTGLFLIA LGSGGIKPLV SSFMGDQFDQ SNKSLAQKAF
160 170 180 190 200
DMFYFTINFG SFFASLSMPL LLKNFGAAVA FGIPGVLMFV ATVFFWLGRK
210 220 230 240 250
RYIHMPPEPK DPHGFLPVIR SALLTKVEGK GNIGLVLALI GGVSAAYALV
260 270 280 290 300
NIPTLGIVAG LCCAMVLVMG FVGAGASLQL ERARKSHPDA AVDGVRSVLR
310 320 330 340 350
ILVLFALVTP FWSLFDQKAS TWILQANDMV KPQWFEPAMM QALNPLLVML
360 370 380 390 400
LIPFNNFVLY PAIERMGVKL TALRKMGAGI AITGLSWIVV GTIQLMMDGG
410 420 430 440 450
SALSIFWQIL PYALLTFGEV LVSATGLEFA YSQAPKAMKG TIMSFWTLSV
460 470 480 490 500
TVGNLWVLLA NVSVKSPTVT EQIVQTGMSV TAFQMFFFAG FAILAAIVFA
510
LYARSYQMQD HYRQAT
Length:516
Mass (Da):56,705
Last modified:March 1, 2003 - v1
Checksum:iEC5BAA7305879100
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014299 Genomic DNA. Translation: AAN53089.1.
RefSeqiNP_715644.1. NC_004347.2.
WP_011070418.1. NC_004347.2.

Genome annotation databases

EnsemblBacteriaiAAN53089; AAN53089; SO_0002.
GeneIDi1167900.
KEGGison:SO_0002.
PATRICi23519695. VBISheOne101494_0002.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014299 Genomic DNA. Translation: AAN53089.1.
RefSeqiNP_715644.1. NC_004347.2.
WP_011070418.1. NC_004347.2.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2XUTX-ray3.62A/B/C1-516[»]
4UVMX-ray3.00A4-516[»]
ProteinModelPortaliQ8EKT7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi211586.SO_0002.

Protein family/group databases

TCDBi2.A.17.4.7. the proton-dependent oligopeptide transporter (pot/ptr) family.

Proteomic databases

PaxDbiQ8EKT7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN53089; AAN53089; SO_0002.
GeneIDi1167900.
KEGGison:SO_0002.
PATRICi23519695. VBISheOne101494_0002.

Phylogenomic databases

eggNOGiENOG4105DUX. Bacteria.
COG3104. LUCA.
HOGENOMiHOG000285186.
KOiK03305.
OMAiVTAFQMF.
OrthoDBiEOG69971K.
PhylomeDBiQ8EKT7.

Family and domain databases

InterProiIPR005279. Dipep/tripep_permease.
IPR020846. MFS_dom.
IPR000109. POT_fam.
IPR018456. PTR2_symporter_CS.
[Graphical view]
PANTHERiPTHR11654. PTHR11654. 2 hits.
PfamiPF00854. PTR2. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 2 hits.
TIGRFAMsiTIGR00924. yjdL_sub1_fam. 1 hit.
PROSITEiPS01022. PTR2_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MR-1Imported.
  2. "Crystal structure of a prokaryotic homologue of the mammalian oligopeptide-proton symporters, PepT1 and PepT2."
    Newstead S., Drew D., Cameron A.D., Postis V.L., Xia X., Fowler P.W., Ingram J.C., Carpenter E.P., Sansom M.S., McPherson M.J., Baldwin S.A., Iwata S.
    EMBO J. 30:417-426(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.62 ANGSTROMS).
  3. Cited for: X-RAY CRYSTALLOGRAPHY (3.00 ANGSTROMS) OF 4-516.

Entry informationi

Entry nameiQ8EKT7_SHEON
AccessioniPrimary (citable) accession number: Q8EKT7
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: March 16, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.