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Q8EKG2 (UBIC_SHEON) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable chorismate--pyruvate lyase

Short name=CL
Short name=CPL
EC=4.1.3.40
Gene names
Name:ubiC
Ordered Locus Names:SO_0131
OrganismShewanella oneidensis
Taxonomic identifier70863 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella

Protein attributes

Sequence length189 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway By similarity. HAMAP MF_01632

Catalytic activity

Chorismate = 4-hydroxybenzoate + pyruvate. HAMAP MF_01632

Pathway

Cofactor biosynthesis; ubiquinone biosynthesis. HAMAP MF_01632

Subcellular location

Cytoplasm By similarity HAMAP MF_01632.

Sequence similarities

Belongs to the ubiC family.

Ontologies

Keywords
   Biological processUbiquinone biosynthesis
   Cellular componentCytoplasm
   LigandPyruvate
   Molecular functionLyase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processubiquinone biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionchorismate lyase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 189189Probable chorismate--pyruvate lyase HAMAP MF_01632
PRO_0000240572

Sites

Binding site771Substrate By similarity
Binding site1151Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8EKG2 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 220E6621420155C6

FASTA18921,364
        10         20         30         40         50         60 
MNVTSLSFPY GESIQWFCAD NTKNLPASPL KEWLLAPGSL TQKLKGCCNE FEVRILGEGQ 

        70         80         90        100        110        120 
CPPLDGEYPN QSAVWVREVL LCLDDVPWVF ARTLIPQSLL STRQADFLGL GTRPLGELLF 

       130        140        150        160        170        180 
SQDSFVPGRI EIARFATNSR LAHLAQSLAQ NVEHELWGRR RYFHHNEEEM FVSEMFLPAA 


EQAIARLCP 

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE014299 Genomic DNA. Translation: AAN53218.1.
RefSeqNP_715773.1. NC_004347.1.

3D structure databases

ProteinModelPortalQ8EKG2.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1168026.
GenomeReviewsGene locus SO_0131 in contig AE014299_GR.
KEGGson:SO_0131.
NMPDRfig|211586.1.peg.128.
PATRIC23519953. VBISheOne101494_0127.
TIGRSO_0131.

Phylogenomic databases

HOGENOMHBG644467.
OMAGRTVIPQ.
ProtClustDBCLSK905613.

Enzyme and pathway databases

BioCycSONE211586:SO_0131-MONOMER.

Family and domain databases

HAMAPMF_01632. UbiC.
[Tree]
InterProIPR007440. Chorismate--pyruvate_lyase.
[Graphical view]
KOK03181.
PfamPF04345. Chor_lyase. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUBIC_SHEON
AccessionPrimary (citable) accession number: Q8EKG2
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: March 1, 2003
Last modified: January 25, 2012
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families