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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Shewanella oneidensis (strain MR-1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381UniRule annotation
Active sitei545 – 5451UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Carbon dioxide fixation

Keywords - Ligandi

Magnesium

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:SO_0274
OrganismiShewanella oneidensis (strain MR-1)
Taxonomic identifieri211586 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
ProteomesiUP000008186: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 881881Phosphoenolpyruvate carboxylasePRO_0000166623Add
BLAST

Proteomic databases

PRIDEiQ8EK30.

Interactioni

Protein-protein interaction databases

STRINGi211586.SO_0274.

Structurei

3D structure databases

ProteinModelPortaliQ8EK30.
SMRiQ8EK30. Positions 5-881.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238648.
KOiK01595.
OMAiCGMGVIA.
OrthoDBiEOG6TJ7T8.
PhylomeDBiQ8EK30.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8EK30-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDMYASLRS NVSMLGQILG DTMRTHLGDS FLEKVEQIRK LAKDSRRGDE
60 70 80 90 100
AAREQMLELL TALPDEELVP FAKAFNQFLN LANLSEQFHT ISRNCDELVC
110 120 130 140 150
VPDPVEQLLG RMLNGRVDQT KMLDCLKTLD IDLVLTAHPT EISRRTLIQK
160 170 180 190 200
YAAIVDCLAE QENNQLSDRE RQQINLRLRQ LIAQIWHTNE IRRERPTPVD
210 220 230 240 250
EARWGLSTIE ESLWHAVPDF LRQLNDQVQE RTGQQLPIDI APVRFSSWMG
260 270 280 290 300
GDRDGNPFVT AKVTQEVLDR NRHAAARLFL KDIVLLVGEL SMEEANDELK
310 320 330 340 350
AYTNNSCEPY RFVLRSLRQK LRDTIDYLNA RIEGHNPEVD KSTLIWQESD
360 370 380 390 400
LKAPLEMLYK SLYDCGMRLI ANGLLLDILR RLACFGIHML RLDIRQDAGR
410 420 430 440 450
HCDVLAELTR YLGMGDFNHW DETEKQAFLL RELSNRRPLI PSNWQPSADV
460 470 480 490 500
AEVLNTCRLI AKHPAKALGS YVISMASKPS DVLTVLLLLK ETGCTHPMRV
510 520 530 540 550
VPLFETLSDL NNAAACITDL LDIDWYRGYT KGMQEVMIGY SDSAKDAGVM
560 570 580 590 600
AAAWAQYRAQ EQLVAVCNQA GVKLTLFHGR GGSIGRGGGP AHKAILSQPP
610 620 630 640 650
GSVDGRIRVT EQGEMIRFKF GLPKLAVQSL ALYTSAVLEA TLLPPPEPKQ
660 670 680 690 700
EWRNCMERIA EESVSAYRGI VREEPDFVAY FRAATPEVEL GKLPLGSRPA
710 720 730 740 750
KRRVDGGIES LRAIPWIFAW SQNRLMLPAW LGAGEALQAA CQRGEIGLLQ
760 770 780 790 800
DMEREWPFFS TRISMLEMVY AKAEPNLARY YETCLVSTNL HHLGETLRQR
810 820 830 840 850
LDLGIKVVLE LTKSDTLMAH TPWNRESVKL RNPYIDPLNF LQTELLARTR
860 870 880
KETSETPASE HVQLALMLTI AGVAAGMRNT G
Length:881
Mass (Da):99,543
Last modified:March 1, 2003 - v1
Checksum:iECA15B92B35DACA6
GO

Sequence cautioni

The sequence AAN53359.2 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014299 Genomic DNA. Translation: AAN53359.2. Different initiation.
RefSeqiNP_715914.2. NC_004347.2.

Genome annotation databases

EnsemblBacteriaiAAN53359; AAN53359; SO_0274.
GeneIDi1168156.
KEGGison:SO_0274.
PATRICi23520253. VBISheOne101494_0265.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014299 Genomic DNA. Translation: AAN53359.2. Different initiation.
RefSeqiNP_715914.2. NC_004347.2.

3D structure databases

ProteinModelPortaliQ8EK30.
SMRiQ8EK30. Positions 5-881.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi211586.SO_0274.

Proteomic databases

PRIDEiQ8EK30.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN53359; AAN53359; SO_0274.
GeneIDi1168156.
KEGGison:SO_0274.
PATRICi23520253. VBISheOne101494_0265.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238648.
KOiK01595.
OMAiCGMGVIA.
OrthoDBiEOG6TJ7T8.
PhylomeDBiQ8EK30.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MR-1.

Entry informationi

Entry nameiCAPP_SHEON
AccessioniPrimary (citable) accession number: Q8EK30
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: March 1, 2003
Last modified: January 7, 2015
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.