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Q8EJU6 (KGUA_SHEON) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Guanylate kinase

EC=2.7.4.8
Alternative name(s):
GMP kinase
Gene names
Name:gmk
Ordered Locus Names:SO_0361
OrganismShewanella oneidensis (strain MR-1) [Reference proteome] [HAMAP]
Taxonomic identifier211586 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella

Protein attributes

Sequence length207 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Essential for recycling GMP and indirectly, cGMP By similarity. HAMAP-Rule MF_00328

Catalytic activity

ATP + GMP = ADP + GDP. HAMAP-Rule MF_00328

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00328.

Sequence similarities

Belongs to the guanylate kinase family.

Contains 1 guanylate kinase-like domain.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processpurine nucleotide metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

guanylate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 207207Guanylate kinase HAMAP-Rule MF_00328
PRO_0000170600

Regions

Domain5 – 184180Guanylate kinase-like
Nucleotide binding12 – 198ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8EJU6 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: B4F09F253E180E9A

FASTA20722,992
        10         20         30         40         50         60 
MTARGNLFIV SAPSGAGKSS LISALLKDKP ADMQVSVSHT TRAPRPGEIN GQHYHFVNVE 

        70         80         90        100        110        120 
EFKALIAQNA FFEWAEVFGN YYGTSRHVIE HTLTQGIDVF LDIDWQGAQQ VKAVMPEAIG 

       130        140        150        160        170        180 
VFILPPSRDE LERRLTGRGQ DSKDVIDSRM AQAVSEMSHY KEYDFIIVND DFDTALADLR 

       190        200 
AIIRSQRLTG ASQIHAQNDM LNDLLAG 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE014299 Genomic DNA. Translation: AAN53446.1.
RefSeqNP_716001.1. NC_004347.2.

3D structure databases

ProteinModelPortalQ8EJU6.
SMRQ8EJU6. Positions 3-206.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING211586.SO_0361.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN53446; AAN53446; SO_0361.
GeneID1168238.
KEGGson:SO_0361.
PATRIC23520427. VBISheOne101494_0352.

Phylogenomic databases

eggNOGCOG0194.
HOGENOMHOG000037638.
KOK00942.
OMAMSHYNEY.
OrthoDBEOG6CP410.
PhylomeDBQ8EJU6.

Family and domain databases

Gene3D3.40.50.300. 2 hits.
HAMAPMF_00328. Guanylate_kinase.
InterProIPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like.
IPR017665. Guanylate_kinase.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF00625. Guanylate_kin. 1 hit.
[Graphical view]
SMARTSM00072. GuKc. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR03263. guanyl_kin. 1 hit.
PROSITEPS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameKGUA_SHEON
AccessionPrimary (citable) accession number: Q8EJU6
Entry history
Integrated into UniProtKB/Swiss-Prot: June 20, 2003
Last sequence update: March 1, 2003
Last modified: July 9, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families