SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8EHZ2

- DEF2_SHEON

UniProt

Q8EHZ2 - DEF2_SHEON

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Peptide deformylase 2
Gene
def2, SO_1062
Organism
Shewanella oneidensis (strain MR-1)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions By similarity.UniRule annotation

Catalytic activityi

Formyl-L-methionyl peptide + H2O = formate + methionyl peptide.UniRule annotation

Cofactori

Binds 1 Fe2+ ion By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi109 – 1091Iron By similarity
Metal bindingi151 – 1511Iron By similarity
Active sitei152 – 1521 By similarity
Metal bindingi155 – 1551Iron By similarity

GO - Molecular functioni

  1. iron ion binding Source: InterPro
  2. peptide deformylase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. translation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Peptide deformylase 2 (EC:3.5.1.88)
Short name:
PDF 2
Alternative name(s):
Polypeptide deformylase 2
Gene namesi
Name:def2
Ordered Locus Names:SO_1062
OrganismiShewanella oneidensis (strain MR-1)
Taxonomic identifieri211586 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
ProteomesiUP000008186: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 181181Peptide deformylase 2UniRule annotation
PRO_0000082835Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi211586.SO_1062.

Structurei

3D structure databases

ProteinModelPortaliQ8EHZ2.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0242.
HOGENOMiHOG000243508.
KOiK01462.
OMAiERSQMPE.
OrthoDBiEOG664CMF.
PhylomeDBiQ8EHZ2.

Family and domain databases

Gene3Di3.90.45.10. 1 hit.
HAMAPiMF_00163. Pep_deformylase.
InterProiIPR000181. Fmet_deformylase.
IPR023635. Peptide_deformylase.
[Graphical view]
PANTHERiPTHR10458. PTHR10458. 1 hit.
PfamiPF01327. Pep_deformylase. 1 hit.
[Graphical view]
PIRSFiPIRSF004749. Pep_def. 1 hit.
PRINTSiPR01576. PDEFORMYLASE.
SUPFAMiSSF56420. SSF56420. 1 hit.
TIGRFAMsiTIGR00079. pept_deformyl. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8EHZ2-1 [UniParc]FASTAAdd to Basket

« Hide

MFKDEMRQTP NKPLPIAVVG EAILKQQAIE VRDFDDTLSQ LASQMAASMV    50
EAKGVGIAAP QVHSPLALFI MASRPNERYP DAPLMEPLVV VNPQIVLRSL 100
QLEKGEEGCL SVPGQRFTIW RPQTIVVRYQ NLAGQWQHSE LTGFIARIFQ 150
HEFDHLQGIT LLERSQMPEQ KLMAQEGKPQ A 181
Length:181
Mass (Da):20,325
Last modified:March 1, 2003 - v1
Checksum:iBF5C27BADEA587C2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014299 Genomic DNA. Translation: AAN54134.1.
RefSeqiNP_716689.1. NC_004347.2.
WP_011071316.1. NC_004347.2.

Genome annotation databases

EnsemblBacteriaiAAN54134; AAN54134; SO_1062.
GeneIDi1168899.
KEGGison:SO_1062.
PATRICi23521771. VBISheOne101494_1019.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014299 Genomic DNA. Translation: AAN54134.1 .
RefSeqi NP_716689.1. NC_004347.2.
WP_011071316.1. NC_004347.2.

3D structure databases

ProteinModelPortali Q8EHZ2.
ModBasei Search...

Protein-protein interaction databases

STRINGi 211586.SO_1062.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAN54134 ; AAN54134 ; SO_1062 .
GeneIDi 1168899.
KEGGi son:SO_1062.
PATRICi 23521771. VBISheOne101494_1019.

Phylogenomic databases

eggNOGi COG0242.
HOGENOMi HOG000243508.
KOi K01462.
OMAi ERSQMPE.
OrthoDBi EOG664CMF.
PhylomeDBi Q8EHZ2.

Family and domain databases

Gene3Di 3.90.45.10. 1 hit.
HAMAPi MF_00163. Pep_deformylase.
InterProi IPR000181. Fmet_deformylase.
IPR023635. Peptide_deformylase.
[Graphical view ]
PANTHERi PTHR10458. PTHR10458. 1 hit.
Pfami PF01327. Pep_deformylase. 1 hit.
[Graphical view ]
PIRSFi PIRSF004749. Pep_def. 1 hit.
PRINTSi PR01576. PDEFORMYLASE.
SUPFAMi SSF56420. SSF56420. 1 hit.
TIGRFAMsi TIGR00079. pept_deformyl. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MR-1.

Entry informationi

Entry nameiDEF2_SHEON
AccessioniPrimary (citable) accession number: Q8EHZ2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2003
Last sequence update: March 1, 2003
Last modified: September 3, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi