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Protein

Purine nucleoside phosphorylase DeoD-type 2

Gene

deoD2

Organism
Shewanella oneidensis (strain MR-1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate.UniRule annotation
Purine deoxynucleoside + phosphate = purine + 2'-deoxy-alpha-D-ribose 1-phosphate.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei5 – 51Purine nucleoside; shared with dimeric partnerBy similarity
Binding sitei21 – 211Phosphate; via amide nitrogenBy similarity
Binding sitei25 – 251PhosphateBy similarity
Binding sitei44 – 441Phosphate; shared with dimeric partnerBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Purine nucleoside phosphorylase DeoD-type 2UniRule annotation (EC:2.4.2.1UniRule annotation)
Short name:
PNP 2UniRule annotation
Gene namesi
Name:deoD2UniRule annotation
Ordered Locus Names:SO_1221
OrganismiShewanella oneidensis (strain MR-1)
Taxonomic identifieri211586 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
ProteomesiUP000008186 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 236236Purine nucleoside phosphorylase DeoD-type 2PRO_0000063160Add
BLAST

Proteomic databases

PaxDbiQ8EHK0.

Interactioni

Subunit structurei

Homohexamer.UniRule annotation

Protein-protein interaction databases

STRINGi211586.SO_1221.

Structurei

3D structure databases

ProteinModelPortaliQ8EHK0.
SMRiQ8EHK0. Positions 2-234.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni88 – 914Phosphate bindingBy similarity
Regioni180 – 1823Purine nucleoside bindingBy similarity
Regioni204 – 2052Purine nucleoside bindingBy similarity

Sequence similaritiesi

Belongs to the PNP/UDP phosphorylase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D3A. Bacteria.
COG0813. LUCA.
HOGENOMiHOG000274896.
KOiK03784.
OMAiPQCLLCG.
OrthoDBiEOG6BKJC5.
PhylomeDBiQ8EHK0.

Family and domain databases

Gene3Di3.40.50.1580. 1 hit.
HAMAPiMF_01627. Pur_nucleosid_phosp.
InterProiIPR004402. DeoD-type.
IPR018017. Nucleoside_phosphorylase.
IPR018016. Nucleoside_phosphorylase_CS.
IPR000845. Nucleoside_phosphorylase_d.
[Graphical view]
PANTHERiPTHR21234. PTHR21234. 1 hit.
PfamiPF01048. PNP_UDP_1. 1 hit.
[Graphical view]
SUPFAMiSSF53167. SSF53167. 1 hit.
TIGRFAMsiTIGR00107. deoD. 1 hit.
PROSITEiPS01232. PNP_UDP_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8EHK0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATPHINAVE GAFAETVLFP GDPLRAKYIA ETFLENVEQV TDVRNMLGFT
60 70 80 90 100
GTYKGKRISV MGSGMGIPSC SIYATELIKD YGVKNLIRVG TCGAISTDVK
110 120 130 140 150
VRDVIIGMGA CTDSQVNRLR FKGQDFAAIA NYELMNAVIE SAKVKGTKIR
160 170 180 190 200
VGNVFSADLF YTPDPQMFDV MEKMGVLGVE MEAAGLYGVA HEFGARALCV
210 220 230
VTVSDHIRTG EKTTSEERQT TFNDMIVMTL DAAITL
Length:236
Mass (Da):25,603
Last modified:March 1, 2003 - v1
Checksum:i3055014ABDC81E9E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014299 Genomic DNA. Translation: AAN54289.1.
RefSeqiNP_716844.1. NC_004347.2.
WP_011071449.1. NC_004347.2.

Genome annotation databases

EnsemblBacteriaiAAN54289; AAN54289; SO_1221.
GeneIDi1169047.
KEGGison:SO_1221.
PATRICi23522098. VBISheOne101494_1172.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014299 Genomic DNA. Translation: AAN54289.1.
RefSeqiNP_716844.1. NC_004347.2.
WP_011071449.1. NC_004347.2.

3D structure databases

ProteinModelPortaliQ8EHK0.
SMRiQ8EHK0. Positions 2-234.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi211586.SO_1221.

Proteomic databases

PaxDbiQ8EHK0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN54289; AAN54289; SO_1221.
GeneIDi1169047.
KEGGison:SO_1221.
PATRICi23522098. VBISheOne101494_1172.

Phylogenomic databases

eggNOGiENOG4105D3A. Bacteria.
COG0813. LUCA.
HOGENOMiHOG000274896.
KOiK03784.
OMAiPQCLLCG.
OrthoDBiEOG6BKJC5.
PhylomeDBiQ8EHK0.

Family and domain databases

Gene3Di3.40.50.1580. 1 hit.
HAMAPiMF_01627. Pur_nucleosid_phosp.
InterProiIPR004402. DeoD-type.
IPR018017. Nucleoside_phosphorylase.
IPR018016. Nucleoside_phosphorylase_CS.
IPR000845. Nucleoside_phosphorylase_d.
[Graphical view]
PANTHERiPTHR21234. PTHR21234. 1 hit.
PfamiPF01048. PNP_UDP_1. 1 hit.
[Graphical view]
SUPFAMiSSF53167. SSF53167. 1 hit.
TIGRFAMsiTIGR00107. deoD. 1 hit.
PROSITEiPS01232. PNP_UDP_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MR-1.

Entry informationi

Entry nameiDEOD2_SHEON
AccessioniPrimary (citable) accession number: Q8EHK0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: March 1, 2003
Last modified: January 20, 2016
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.