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Q8EH81 (RNC_SHEON) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonuclease 3

EC=3.1.26.3
Alternative name(s):
Ribonuclease III
Short name=RNase III
Gene names
Name:rnc
Ordered Locus Names:SO_1348
OrganismShewanella oneidensis (strain MR-1) [Reference proteome] [HAMAP]
Taxonomic identifier211586 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella

Protein attributes

Sequence length226 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon By similarity. HAMAP-Rule MF_00104

Catalytic activity

Endonucleolytic cleavage to 5'-phosphomonoester. HAMAP-Rule MF_00104

Cofactor

Mg2+ By similarity. HAMAP-Rule MF_00104

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00104

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00104.

Sequence similarities

Contains 1 DRBM (double-stranded RNA-binding) domain.

Contains 1 RNase III domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 226226Ribonuclease 3 HAMAP-Rule MF_00104
PRO_0000228579

Regions

Domain7 – 129123RNase III
Domain156 – 22671DRBM

Sites

Active site461 Potential
Active site1181 By similarity
Metal binding421Magnesium By similarity
Metal binding1151Magnesium By similarity
Metal binding1181Magnesium By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8EH81 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 7772258B8C0C12C5

FASTA22625,297
        10         20         30         40         50         60 
MEPIKNLPRL CRTLGYEFKN LDLLTQALTH RSAANKHNER LEFLGDSILS IVISDALYHQ 

        70         80         90        100        110        120 
FPKATEGDLS RMRATLVRGD TLTLIAQAFK LGDYLFLGPG ELKSGGFRRE SILADAVEAI 

       130        140        150        160        170        180 
IGAIYLDSDL EVCRQLLLNW YAERLAEIQP GINQKDAKTL LQEYLQGLKK PLPDYQVINI 

       190        200        210        220 
EGDAHDQTFT VECRIDDLSQ SVIGVASSRR KAEQIAAAQV LELLKK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE014299 Genomic DNA. Translation: AAN54413.1.
RefSeqNP_716968.1. NC_004347.2.

3D structure databases

ProteinModelPortalQ8EH81.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING211586.SO_1348.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN54413; AAN54413; SO_1348.
GeneID1169169.
KEGGson:SO_1348.
PATRIC23522350. VBISheOne101494_1297.

Phylogenomic databases

eggNOGCOG0571.
HOGENOMHOG000246809.
KOK03685.
OMARACELPR.
OrthoDBEOG6T1WVS.
ProtClustDBPRK00102.

Family and domain databases

Gene3D1.10.1520.10. 1 hit.
3.30.160.20. 1 hit.
HAMAPMF_00104. RNase_III.
InterProIPR014720. dsRNA-bd_dom.
IPR011907. RNase_III.
IPR000999. RNase_III_dom.
[Graphical view]
PANTHERPTHR11207. PTHR11207. 1 hit.
PfamPF00035. dsrm. 1 hit.
PF14622. Ribonucleas_3_3. 1 hit.
[Graphical view]
SMARTSM00358. DSRM. 1 hit.
SM00535. RIBOc. 1 hit.
[Graphical view]
SUPFAMSSF69065. SSF69065. 1 hit.
TIGRFAMsTIGR02191. RNaseIII. 1 hit.
PROSITEPS50137. DS_RBD. 1 hit.
PS00517. RNASE_3_1. 1 hit.
PS50142. RNASE_3_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRNC_SHEON
AccessionPrimary (citable) accession number: Q8EH81
Entry history
Integrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: March 1, 2003
Last modified: April 16, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families