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Q8EGG3 (Q8EGG3_SHEON) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase HAMAP MF_00387
Short name=UDP-N-acetylglucosamine acyltransferase HAMAP MF_00387
EC=2.3.1.129 HAMAP MF_00387
Gene names
Name:lpxA HAMAP MF_00387 EMBL AAN54696.1
Ordered Locus Names:SO_1641
OrganismShewanella oneidensis
Taxonomic identifier70863 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length256 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. HAMAP MF_00387 SAAS SAAS010137

Catalytic activity

(R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] + UDP-N-acetylglucosamine = [acyl-carrier-protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine. HAMAP MF_00387 SAAS SAAS010137

Pathway

Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 1/6. HAMAP MF_00387 SAAS SAAS010137

Subunit structure

Homotrimer By similarity. HAMAP MF_00387 SAAS SAAS010137

Subcellular location

Cytoplasm By similarity HAMAP MF_00387.

Sequence similarities

Belongs to the transferase hexapeptide repeat family. LpxA subfamily. HAMAP MF_00387

Sequences

Sequence LengthMass (Da)Tools
Q8EGG3 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 2953C9D3F42DD51E

FASTA25627,670
        10         20         30         40         50         60 
MIDTLAFVHP DAKIGKNVTI GPWSYVGAGV EIGDDCWLSS HVVVKGPTVI GKGNRIFQFA 

        70         80         90        100        110        120 
SVGEECQDKK YAGEPTRLII GDNNVIREHV TIHRGTVQDN SETRIGSNNL FMNYVHIAHD 

       130        140        150        160        170        180 
CVVGNNVIMA NNASIAGHVH VGDWAILGGM TGVHQFVHIG AHAFTAGCSL LLQDVPPFVM 

       190        200        210        220        230        240 
AAGQPAIPRG LNSEGMKRRG FSKESQLAVR RAYKTLYRSS LTVEEAVEAL AEDAQNDAQV 

       250 
KLLVEFVKSS GRGIIR

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE014299 Genomic DNA. Translation: AAN54696.1.
RefSeqNP_717252.1. NC_004347.1.

3D structure databases

HSSPHSSP built from PDB template 1LXA based on UniProtKB P10440.
ProteinModelPortalQ8EGG3.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1169435.
GenomeReviewsGene locus SO_1641 in contig AE014299_GR.
KEGGson:SO_1641.
NMPDRfig|211586.1.peg.1508.
PATRIC23522916. VBISheOne101494_1580.
TIGRSO_1641.

Phylogenomic databases

HOGENOMHBG659295.
OMAREFCTFN.
ProtClustDBPRK05289.

Enzyme and pathway databases

BioCycSONE211586:SO_1641-MONOMER.

Family and domain databases

HAMAPMF_00387. LpxA.
[Tree]
InterProIPR001451. Hexapep_transf.
IPR018357. Hexapep_transf_CS.
IPR010137. Lipid_A_lpxA.
IPR011004. Trimer_LpxA-like.
[Graphical view]
KOK00677.
PfamPF00132. Hexapep. 4 hits.
[Graphical view]
PIRSFPIRSF000456. UDP-GlcNAc_acltr. 1 hit.
SUPFAMSSF51161. Trimer_LpxA_like. 1 hit.
TIGRFAMsTIGR01852. Lipid_A_lpxA. 1 hit.
PROSITEPS00101. HEXAPEP_TRANSFERASES. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ8EGG3_SHEON
AccessionPrimary (citable) accession number: Q8EGG3
Entry history
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: December 14, 2011
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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