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Q8EG26 (SYQ_SHEON) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamine--tRNA ligase

EC=6.1.1.18
Alternative name(s):
Glutaminyl-tRNA synthetase
Short name=GlnRS
Gene names
Name:glnS
Ordered Locus Names:SO_1786
OrganismShewanella oneidensis (strain MR-1) [Reference proteome] [HAMAP]
Taxonomic identifier211586 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella

Protein attributes

Sequence length556 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln). HAMAP-Rule MF_00126

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00126

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00126.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processglutaminyl-tRNA aminoacylation

Inferred from electronic annotation. Source: InterPro

glutamyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glutamine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 556556Glutamine--tRNA ligase HAMAP-Rule MF_00126
PRO_0000195850

Regions

Motif36 – 4611"HIGH" region HAMAP-Rule MF_00126
Motif273 – 2775"KMSKS" region HAMAP-Rule MF_00126

Sites

Binding site2761ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8EG26 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 3A7E689DACCAFFF0

FASTA55664,103
        10         20         30         40         50         60 
MSHVDTEVRP SNFIRNIIDE DLKSGKHTNV QTRFPPEPNG YLHIGHAKSI CLNFGIARDY 

        70         80         90        100        110        120 
QGLCNLRFDD TNPEKEDIDY VNSIQADVRW LGFQWDGEVR YSSNYFDQLH QYAVELINKG 

       130        140        150        160        170        180 
LAYVCFLNAD ETREYRGTLK EPGKNSPYRD TPVEENLRLF GKMRLGEFKE GECALRAKID 

       190        200        210        220        230        240 
MASPFMCMRD PVIYRIRFAH HHQTGDKWCI YPMYDFTHCI SDALEHITHS LCTLEFQDNR 

       250        260        270        280        290        300 
RLYDWVLDNL DDFQAPNRTR QYEFSRLNLE YTLMSKRKLN DLVTRKLVTG WDDPRMPTIA 

       310        320        330        340        350        360 
GLRRRGYTPA SIREFCQRIG ITKQENMIEA AMLDACIREE LNEHAPRAMA VLRPLKVVIE 

       370        380        390        400        410        420 
NYPEGQIETI QAASHPSDES MGTRELAFGR EIFIDVADFR EEANKQYKRL VMGKEVRLRN 

       430        440        450        460        470        480 
AYVIKAERCD KDSEGNITTV YCSYDADTLG KNPADGRKVK GVIHWVEATT AKPAQFRLYQ 

       490        500        510        520        530        540 
RLFTDPNPAA AETVDEVLNP NSLEVVNGLV EASLANAPAE KAYQFEREGY FCADNKDSSA 

       550 
DHLVFNLTVA LRDSFE 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE014299 Genomic DNA. Translation: AAN54839.1.
RefSeqNP_717395.1. NC_004347.2.

3D structure databases

ProteinModelPortalQ8EG26.
SMRQ8EG26. Positions 11-554.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING211586.SO_1786.

Proteomic databases

PRIDEQ8EG26.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN54839; AAN54839; SO_1786.
GeneID1169559.
KEGGson:SO_1786.
PATRIC23523189. VBISheOne101494_1716.

Phylogenomic databases

eggNOGCOG0008.
HOGENOMHOG000259232.
KOK01886.
OMASREIYID.
OrthoDBEOG6DRPF7.
PhylomeDBQ8EG26.

Family and domain databases

Gene3D1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
HAMAPMF_00126. Gln_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERPTHR10119. PTHR10119. 1 hit.
PfamPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view]
PRINTSPR00987. TRNASYNTHGLU.
SUPFAMSSF50715. SSF50715. 1 hit.
TIGRFAMsTIGR00440. glnS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYQ_SHEON
AccessionPrimary (citable) accession number: Q8EG26
Entry history
Integrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: March 1, 2003
Last modified: July 9, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries