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Q8EFU5 (SPEA_SHEON) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Biosynthetic arginine decarboxylase

Short name=ADC
EC=4.1.1.19
Gene names
Name:speA
Ordered Locus Names:SO_1870
OrganismShewanella oneidensis (strain MR-1) [Reference proteome] [HAMAP]
Taxonomic identifier211586 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella

Protein attributes

Sequence length637 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the biosynthesis of agmatine from arginine By similarity. HAMAP-Rule MF_01417

Catalytic activity

L-arginine = agmatine + CO2. HAMAP-Rule MF_01417

Cofactor

Magnesium By similarity. HAMAP-Rule MF_01417

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01417

Sequence similarities

Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 637637Biosynthetic arginine decarboxylase HAMAP-Rule MF_01417
PRO_0000149977

Regions

Region286 – 29611Substrate-binding Potential

Amino acid modifications

Modified residue1011N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8EFU5 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 8EAE2CF59061F7B8

FASTA63771,004
        10         20         30         40         50         60 
MNDWSIEAAR AGYNVTHWSQ GFYGISDEGE VTVSPDPKNP DHKIGLNELA KDMVKAGVAL 

        70         80         90        100        110        120 
PVLVRFPQIL HHRVNSLCQA FDQAIQKYEY QADYLLVYPI KVNQQKTVVE EILASQASKE 

       130        140        150        160        170        180 
VPQLGLEAGS KPELMAVLAM AQKASSVIVC NGYKDNEYIR LALIGEKLGH KVYIVLEKLS 

       190        200        210        220        230        240 
ELKMVLAESK RLGVKPRLGL RARLAFQGKG KWQASGGEKS KFGLSAAQIL TVVDQLKQSD 

       250        260        270        280        290        300 
MLDSLQLLHF HLGSQIANIR DIRQGVSEAA RFYCELRELG ASINCFDVGG GLAVDYDGTR 

       310        320        330        340        350        360 
SQSNNSMNYG LSEYANNIVN VLTDICNEYE QPMPRIISES GRHLTAHHAV LITDVIGTEA 

       370        380        390        400        410        420 
YQVEDIQPPE EESPQLLHNM WQSWTELSGR ADQRALIEIY HDSQSDLQEA QSLFALGQLS 

       430        440        450        460        470        480 
LAERAWAEQA NLRVCHEVQG LLSTKNRYHR PIIDELNEKL ADKFFVNFSL FQSLPDAWGI 

       490        500        510        520        530        540 
DQVFPVLPLS GLDKAPERRA VMLDITCDSD GIVDQYVDGQ GIETTLPVPA WSAESPYLIG 

       550        560        570        580        590        600 
FFMVGAYQEI LGDMHNLFGD TNSAVVSIEE NGMTNIESVL AGDTVADVLR YVNLDAVDFM 

       610        620        630 
RTYEELVNQH IAEDERAQIL EELQVGLKGY TYLEDFS 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE014299 Genomic DNA. Translation: AAN54922.1.
RefSeqNP_717478.1. NC_004347.2.

3D structure databases

ProteinModelPortalQ8EFU5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING211586.SO_1870.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN54922; AAN54922; SO_1870.
GeneID1169637.
KEGGson:SO_1870.
PATRIC23523379. VBISheOne101494_1798.

Phylogenomic databases

eggNOGCOG1166.
HOGENOMHOG000029191.
KOK01585.
OMAMIHFHIG.
OrthoDBEOG676Z0R.
ProtClustDBPRK05354.

Family and domain databases

Gene3D2.40.37.10. 2 hits.
HAMAPMF_01417. SpeA.
InterProIPR009006. Ala_racemase/Decarboxylase_C.
IPR002985. Arg_decrbxlase.
IPR022643. De-COase2_C.
IPR022644. De-COase2_N.
IPR000183. Orn/DAP/Arg_de-COase.
[Graphical view]
PfamPF02784. Orn_Arg_deC_N. 1 hit.
PF00278. Orn_DAP_Arg_deC. 1 hit.
[Graphical view]
PIRSFPIRSF001336. Arg_decrbxlase. 1 hit.
PRINTSPR01180. ARGDCRBXLASE.
PR01179. ODADCRBXLASE.
TIGRFAMsTIGR01273. speA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSPEA_SHEON
AccessionPrimary (citable) accession number: Q8EFU5
Entry history
Integrated into UniProtKB/Swiss-Prot: March 29, 2004
Last sequence update: March 1, 2003
Last modified: February 19, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families