Q8EF14 (Q8EF14_SHEON) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Cystathionine beta-lyase EMBL AAN55233.1

Gene names

Name:	metC EMBL AAN55233.1
Ordered Locus Names:	SO_2191

Organism

Shewanella oneidensis

Taxonomic identifier

70863 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length	399 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Pyridoxal phosphate By similarity. RuleBase RU004507
Sequence similarities	Belongs to the trans-sulfuration enzymes family. RuleBase RU004079

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU004507
Molecular function	Lyase EMBL AAN55233.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	cellular amino acid metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	cystathionine beta-lyase activity Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8EF14 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: FA12C9F016364790	FASTA	399	44,189
	10 20 30 40 50 60 MTDKHQLATQ IVSVGRDKKW TKGVINPPVF RASTIVFDTM EDMRHAAKNK TNGEMFYGRR 70 80 90 100 110 120 GTPTHFAFQA AVSELEGGAG TALYPSGAAA ISAALLSFLQ AGDHLLMVDS VYEPTRDFCS 130 140 150 160 170 180 HILAGFNIET TYYDPLIGEG IRALIRPNTK VLFLESPGSI TMEVQDVPTL CRIAHEHGLV 190 200 210 220 230 240 TILDNTWASP INSKPFEMGV DVSIQAATKY IVGHSDVMIG TATANEQYWP QLRERSYLLG 250 260 270 280 290 300 QTTSPDDVYL ATRGLRTLGV RMAQHEKNAL KVANWLQTRP EVDHLRHPAF ETCPGHEFFK 310 320 330 340 350 360 RDFSASNGLF SFVLKQGDQE AVTALVENMQ HFKMGFSWGG YESLILGIFG IERIRSATKW 370 380 390 DASKPLIRVH IGLEDPEDLI ADLSAGFERF NAVLAAKVK

References

[1]

"Genome sequence of the dissimilatory metal ion-reducing bacterium Shewanella oneidensis." Heidelberg J.F., Paulsen I.T., Nelson K.E., Gaidos E.J., Nelson W.C., Read T.D., Eisen J.A., Seshadri R., Ward N.L., Methe B.A., Clayton R.A., Meyer T., Tsapin A., Scott J., Beanan M.J., Brinkac L.M., Daugherty S.C., DeBoy R.T. , Dodson R.J., Durkin A.S., Haft D.H., Kolonay J.F., Madupu R., Peterson J.D., Umayam L.A., White O., Wolf A.M., Vamathevan J.J., Weidman J.F., Impraim M., Lee K., Berry K.J., Lee C., Mueller J., Khouri H.M., Gill J., Utterback T.R., McDonald L.A., Feldblyum T.V., Smith H.O., Venter J.C., Nealson K.H., Fraser C.M. Nat. Biotechnol. 20:1118-1123(2002) [PubMed: 12368813] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MR-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014299 Genomic DNA. Translation: AAN55233.1.
RefSeq	NP_717789.1. NC_004347.1.
3D structure databases
HSSP	HSSP built from PDB template 1CL2 based on UniProtKB P06721.
ProteinModelPortal	Q8EF14.
SMR	Q8EF14. Positions 6-390.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1169928.
GenomeReviews	Gene locus SO_2191 in contig AE014299_GR.
KEGG	son:SO_2191.
NMPDR	fig|211586.1.peg.1991.
PATRIC	23524004. VBISheOne101494_2108.
TIGR	SO_2191.
Phylogenomic databases
HOGENOM	HBG754729.
OMA	REQSYLM.
ProtClustDB	PRK09028.
Enzyme and pathway databases
BioCyc	SONE211586:SO_2191-MONOMER.
Family and domain databases
InterPro	IPR000277. Cys/Met-Metab_PyrdxlP-dep_enz. IPR006233. Cys_b_lyase_bac. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K01760.
PANTHER	PTHR11808:SF8. Cys_b_lyase_bac. 1 hit. PTHR11808. Cys_Met_Meta_PP. 1 hit.
Pfam	PF01053. Cys_Met_Meta_PP. 1 hit. [Graphical view]
PIRSF	PIRSF001434. CGS. 1 hit.
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01324. Cysta_beta_ly_B. 1 hit.
PROSITE	PS00868. CYS_MET_METAB_PP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8EF14_SHEON

Accession

Primary (citable) accession number: Q8EF14

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	December 14, 2011
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)